Researchers Uncover Assembly and Architecture of Endogenous NMDA Receptors in Adult Cerebral Cortex and Hippocampus

Learning and memory are fundamental brain functions that underlie human cognition and perception of the world, which rely on development- and activity-dependent synaptic plastic...

Meet Injectable Supramolecular Hydrogel of Abemaciclib-Loaded Peptide-NLG919 Nanofibers for Neoadjuvant Immunotherapy of Triple-Negative Breast Cancer

The efficacy of immunotherapy against triple-negative breast cancer (TNBC) heavily relies on intratumoral infiltration of cytotoxic T lymphocytes (CTLs). Although the neoadjuvan...

Engineered Extracellular Vesicles Loaded in Boronated Cyclodextrin Framework: Novel Design for Pulmonary Delivery

Given that BCF was synthesized from cyclodextrins, BCF was an ideal delivery carrier for small molecule drugs. Additionally, the amphipathic nature of EVs’membrane provided a v...