They were also asked whether the participants' parents, siblings or children were ever diagnosed with major depression, bipolar disorder, anxiety, post-traumatic stress disorder, obsessive-compulsive disorder or other mood or psychiatric disorders.

In this case, that mainly includes the earnest David, a digital ad salesman and devoted family man with controlled obsessive-compulsive disorder and a low threshold for embarrassment, the latter of which Benji repeatedly tests.

More than eight million people in England are taking antidepressants, for depression, anxiety, obsessive-compulsive disorder and other conditions - a million more than five years ago.

And if this is indeed “Mr. Monk’s Last Case,” I’d give Tony Shalhoub, who has won three Emmys for playing the detective tormented by obsessive-compulsive disorder, a chance to prevail.

The same year, they published a case report in Molecular Psychiatry describing autoantibodies against certain cells in the hippocampus, isolated from the CSF of a young woman with obsessive-compulsive disorder.