In this study, Padhi et al. demonstrate the potential of metagenomics-based approaches for the discovery of natural products from complex ecosystems.

This study shows that the Campylobacter jejuni-derived genotoxin named cytolethal distending toxin promotes colorectal cancer metastasis.

A recent study shows that the commensal bacterium Lactiplantibacillus plantarum recognizes the foregut of the fruit fly as its physical niche via sugar-binding adhesins.

In a recent study, Lin et al. uncovered that a single substitution in the bovine influenza H5N1 haemagglutinin protein switches the specificity to human receptors.

A recent study found that soil microbial communities show consistent and predictable responses to extreme climatic events.

In this journal club, Lucy Thorne discusses a paper that compares pandemic and non-pandemic HIV and shows that the ability of pandemic HIV to effectively evade the host’s innate immune response is a key factor in its pandemic potential.

This Genome Watch article highlights recent findings that expand the known diversity of methanogenic archaea and the metagenomic evidence that led to their identification and cultivation.

In this Review, Timm, Russell and Hultgren provide an overview of the bacterial and host factors contributing to the development of urinary tract infections, and they highlight new treatment strategies currently under development.

In this Review, Flemming and colleagues aim to explore the roles of microbial extracellular polymeric substances in the environment, in technology and in medicine.

In this Review, Crawford and Turocy examine diverse small molecule metabolites produced by the human microbiota, their role as potential risk factors for cancer development as well as novel mechanistic insights demonstrating their association with gastrointestinal cancer.

In this Review, Zhou, Tran et al. provide a comprehensive overview of the metabolic reactions by which microorganisms transform inorganic sulfur compounds across varied microbiomes and ecosystems, and explore the link between sulfur cycling microorganisms and climate change.