Featured
-
-
Article
| Open Access
Exploring PDK3 inhibition in lung cancer through drug repurposing for potential therapeutic interventions
- Zeba Firdos Khan
- , Aanchal Rathi
- & Md. Imtaiyaz Hassan
-
Article
| Open Access
Binding interaction of sodium benzoate, potassium sorbate and sodium dihydrogen citrate with BSA as food preservatives: in Vitro analysis and computational studies
- Leila Emami
- , Elaheh Khodarahimi
- & Marzieh Rashedinia
-
Article
| Open Access
Cytoskeletal regulation on polycaprolactone/graphene porous scaffolds for bone tissue engineering
- Hendrik Setia Budi
- , Silvia Anitasari
- & Shuntaro Yamada
-
Article
| Open Access
Muscular robusticity and strength in the lower extremities in elite handball players
- Annamaria Zsakai
- , Fanny Zselyke Ratz-Sulyok
- & Tamas Szabo
-
Article
| Open Access
Molecular insights into the inhibition of angiotensin-converting enzyme 1 by hemopressin peptides
- Priya Antony
- , Bincy Baby
- & Ranjit Vijayan
-
Article
| Open Access
Enzyme stabilisation due to incorporation of a fluorinated non-natural amino acid at the protein surface
- Arka Mukhopadhyay
- , Yiwen Li
- & Paul A. Dalby
-
Article
| Open Access
Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2
- Carina Lotz-Jenne
- , Roland Lange
- & Aengus Mac Sweeney
-
Article
| Open Access
Hepatocellular carcinoma antibodies preferably identify nitro-oxidative-DNA lesions induced by 4-Chloro-orthophenylenediamine and DEANO
- Shifa Khan
- , Asif Ali
- & Safia Habib
-
Article
| Open Access
Curcuma sumonii sp. nov., and C. wanchaii sp. nov. (Zingiberaceae), two new taxa of Curcuma subgen. Curcuma from Thailand
- Piyaporn Saensouk
- , Surapon Saensouk
- & Phetlasy Souladeth
-
Article
| Open Access
The homodimerization domain of the Stl repressor is crucial for efficient inhibition of mycobacterial dUTPase
- Zoé S. Tóth
- , Ibolya Leveles
- & András Benedek
-
Article
| Open Access
Parameterized hypercomplex convolutional network for accurate protein backbone torsion angle prediction
- Wei Yang
- , Shujia Wei
- & Lei Zhang
-
Article
| Open Access
Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents
- Xueqian Bai
- , Jinghan Wang
- & Tianyi Zhang
-
Article
| Open Access
Broadening alloselectivity of T cell receptors by structure guided engineering
- Vijaykumar Karuppiah
- , Dhaval Sangani
- & Stephen Harper
-
Article
| Open Access
Revealing the structural microenvironment of high metastatic risk uveal melanomas following decellularisation
- Karen Aughton
- , Joshua Hattersley
- & Helen Kalirai
-
Article
| Open Access
Structural dynamics of human deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase)
- Ravdna Sarre
- , Olena Dobrovolska
- & Johan Isaksson
-
Article
| Open Access
Acute hyperlipidemia has transient effects on large-scale bone regeneration in male mice
- Luciana Yamamoto de Almeida
- , Catharine Dietrich
- & Janice S. Lee
-
Article
| Open Access
Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models
- Melissa M. Matthews
- , Tae Gyun Kim
- & Matthias Wolf
-
Article
| Open Access
Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure propensities
- Juliano Morimoto
- & Zuzanna Pietras
-
Article
| Open Access
The Tmem16a chloride channel is required for mucin maturation after secretion from goblet-like cells in the Xenopus tropicalis tadpole skin
- Eamon Dubaissi
- , Emma N. Hilton
- & David J Thornton
-
Article
| Open Access
Rational design and synthesis of new pyrrolone candidates as prospective insecticidal agents against Culex pipiens L. Larvae
- Mohamed H. Hekal
- , Ahmed I. Hashem
- & Yasmeen M. Ali
-
Article
| Open Access
Multitargeted docking approach reveals droxidopa against DNA replication and repair-related protein of cervical cancer
- Ahad Amer Alsaiari
- , Fawaz M. Almufarriji
- & Mohammed Ageeli Hakami
-
Article
| Open Access
Molecular dynamics simulations involving different β-propeller mutations reported in Swiss and French patients correlate with their disease phenotypes
- Finola Priyadharshini Chandrasekaran
- & Everette Jacob Remington Nelson
-
Article
| Open Access
Investigating the causal relationship between inflammatory bowel disease and simple appendicitis using Mendelian randomization
- Yawei Zhang
- , Lichao Yang
- & Lianwen Yuan
-
Article
| Open Access
Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8
- Merlyn Latimer-Smith
- , Paula S. Salgado
- & Kamel El Omari
-
Article
| Open Access
Exploring the ability of the MD+FoldX method to predict SARS-CoV-2 antibody escape mutations using large-scale data
- L. América Chi
- , Jonathan E. Barnes
- & F. Marty Ytreberg
-
Article
| Open Access
Morphological characteristics and distribution identification of telocytes in Tibetan sheep testis and epididymis
- Long Ma
- , Ligang Yuan
- & Xiaolong Qie
-
Article
| Open Access
Structural characterization of green fluorescent protein in the I-state
- Ryota Takeda
- , Erika Tsutsumi
- & Kazuki Takeda
-
Article
| Open Access
Preliminary study on hand dimensions as potential predictors of female populations native to forest and savanna zones in Ghana
- Samuel Bimpong
- , Chrissie Stansie Abaidoo
- & Thomas K. Diby
-
Article
| Open Access
The effect of hemicelluloses on biosynthesis, structure and mechanical performance of bacterial cellulose-hemicellulose hydrogels
- Vadym Chibrikov
- , Piotr Mariusz Pieczywek
- & Artur Zdunek
-
Article
| Open Access
Structural brain characteristics of epilepsy patients with comorbid migraine without aura
- Shujiang Zhang
- , Wenyu Liu
- & Dong Zhou
-
Article
| Open Access
Assessing the role of evolutionary information for enhancing protein language model embeddings
- Kyra Erckert
- & Burkhard Rost
-
Article
| Open Access
Rutin of Moringa oleifera as a potential inhibitor to Agaricus bisporus tyrosinase as revealed from the molecular dynamics of inhibition
- Reyad M. El-Sharkawy
- , Abdalla E. El-Hadary
- & Ashraf S. A. El-Sayed
-
Article
| Open Access
Bioinformatics and computational studies of chabamide F and chabamide G for breast cancer and their probable mechanisms of action
- Pallobi Ray
- , Dipto Kumer Sarker
- & Shaikh Jamal Uddin
-
Article
| Open Access
Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody
- Oscar Jungholm
- , Carolina Trkulja
- & Owe Orwar
-
Article
| Open Access
Structure-based drug-development study against fibroblast growth factor receptor 2: molecular docking and Molecular dynamics simulation approaches
- Anas Shamsi
- , Mohd Shahnawaz Khan
- & Rizwan Hasan Khan
-
Article
| Open Access
Rational design of environmentally responsive antibodies with pH-sensing synthetic amino acids
- Yuya Isoda
- , Kazumasa Ohtake
- & Yasuhisa Shiraishi
-
Article
| Open Access
Finite element analysis of fixation stability according to reduction position for internal fixation of intertrochanteric fractures
- Cheol-Jeong Kim
- , Jung Sub Lee
- & Chiseung Lee
-
Article
| Open Access
Structure and dimerization properties of the plant-specific copper chaperone CCH
- Dominik Dluhosch
- , Lisa Sophie Kersten
- & Georg Groth
-
Article
| Open Access
Spatial distribution of active compounds in stratum corneum—partitioning between corneocytes and lipid matrix
- Peter Sjövall
- , Sebastien Gregoire
- & Gustavo S. Luengo
-
Article
| Open Access
Structural basis of divergent substrate recognition and inhibition of human neurolysin
- Ke Shi
- , Sounak Bagchi
- & Hideki Aihara
-
Article
| Open Access
Unveiling novel insights into human IL-6 − IL-6R interaction sites through 3D computer-guided docking and systematic site mutagenesis
- Kaitong Li
- , Junyu Cai
- & Jiannan Feng
-
Article
| Open Access
The crystal structure of Acinetobacter baumannii bacterioferritin reveals a heteropolymer of bacterioferritin and ferritin subunits
- Huili Yao
- , Suliat Alli
- & Mario Rivera
-
Article
| Open Access
Antox targeting AGE/RAGE cascades to restore submandibular gland viability in rat model of type 1 diabetes
- Marwa M. Ahmad
- , Heba A. Hassan
- & Manal Mohammad Morsy
-
Article
| Open Access
Bayesian reweighting of biomolecular structural ensembles using heterogeneous cryo-EM maps with the cryoENsemble method
- Tomasz Włodarski
- , Julian O. Streit
- & John Christodoulou
-
Article
| Open Access
Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer
- Bianca Kerschbaumer
- , Peter Macheroux
- & Aleksandar Bijelic
-
Article
| Open Access
Computational studies on the catalytic potential of the double active site for enzyme engineering
- Naveen Banchallihundi Krishna
- , Lalitha Roopa
- & Gopenath T S
-
Article
| Open Access
Examine stability polyvinyl alcohol-stabilized nanosuspensions to overcome the challenge of poor drug solubility utilizing molecular dynamic simulation
- Sedigheh Abdollahi
- , Heidar Raissi
- & Farzaneh Farzad
-
Article
| Open Access
Tunneling nanotube-driven complete regeneration of murine fetal skin
- Yukari Nakajima
- , Shuichi Obata
- & Kazuo Kishi
-
Article
| Open Access
Atomic insights into the signaling landscape of E. coli PhoQ histidine kinase from molecular dynamics simulations
- Symela Lazaridi
- , Jing Yuan
- & Thomas Lemmin
DMSO might impact ligand binding, capsid stability, and RNA interaction in viral preparations