For optimal liver detoxification, it is essential that all three phases are open and working in harmony. Problems in liver detoxification occur if phase 1 is too fast, yet phase 2 detoxification pathways are too slow or if phase 3 detox is clogged. Excess inflammation can cause the 2.5 detox door to close. Many people will feel worse if they do a liver detox program yet have inflammation or a sluggish gallbladder
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