Heba Alagha

Acibadem University, Biomedical Engineering, Post-Doc

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Master patience and you can master anything.
Address: Istanbul, İstanbul, Turkey

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Amir Manbachi

Johns Hopkins University

Gwen Robbins Schug

University of North Carolina at Greensboro

Jesper Hoffmeyer

University of Copenhagen

SIVA UMAPATHY

Indian Institute of Science

Neelam Jain

Amity University Rajasthan

Richard Cloutier

Université du Québec à Rimouski

Isad Saric

University of Sarajevo

Alaa Al-Charrakh

University of Babylon

Arthur B. Novaes

Universidade de São Paulo

Pål Kristian Selbo

Oslo University Hospital, Norwegian Radiumhospitalet

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Papers by Heba Alagha

An In vitro Study on the Antibacterial Effect of a Combined Photodynamic and Sonodynamic Therapy Using IR780 Iodide-loaded Mesoporous Silica Nanoparticles Against P. aeruginosa and Multi-Drug Resistant P. aeruginosa

Recent advances in anti-infective drug discovery, Jun 13, 2024

Inactivation of planktonic cells and inhibitory effect on post-treatment biofilm formation of methicillin-resistant Staphylococcus aureus by photodynamic treatment with IR780 iodide loaded mesoporous silica nanoparticles and near infrared light

Journal of Microbiological Methods

Photothermal ablation of liver tissue with 1940-nm thulium fiber laser: anex vivostudy on lamb liver

Journal of Biomedical Optics, 2016

The purpose of this study was to investigate the ablation efficiency of 1940-nm thulium fiber las... more The purpose of this study was to investigate the ablation efficiency of 1940-nm thulium fiber laser on liver tissue, while utilizing a real-time measurement system to monitor the temperature rise in adjacent tissues. Thulium fiber laser was delivered to lamb liver tissue samples via 400-μm bare tip fiber in contact mode. Eight different laser parameter combinations [power, continuous-wave ðcwÞ∕pulsed-modulated (pm) mode, and exposure time] were used. Exposure times were chosen to give the same total applied energy of 4 J for comparative purposes. Following laser irradiations, tissues were processed and stained with hematoxylin and eosin for macroscopic evaluation of ablation areas and total altered areas, and ablation efficiencies were calculated. Temperature of the nearby tissue at a distance of 1 mm from the fiber was measured, and rate of temperature change was calculated. A strong correlation between the rate of temperature change and ablation area was noted. Thermal effects increased with increasing power for both modes. The continuous-wave mode yielded higher ablation efficiencies than the pulse-modulated mode. Histological evaluation revealed a narrow vacuolization zone and negligible carbonization for higher-power values.

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Photothermal ablation of liver tissue with 1940-nm thulium fiber laser: an ex vivo study on lamb liver

The purpose of this study was to investigate the ablation efficiency of 1940-nm thulium fiber las... more The purpose of this study was to investigate the ablation efficiency of 1940-nm thulium fiber laser on liver tissue, while utilizing a real-time measurement system to monitor the temperature rise in adjacent tissues. Thulium fiber laser was delivered to lamb liver tissue samples via 400-μm bare tip fiber in contact mode. Eight different laser parameter combinations [power, continuous-wave ðcwÞ∕pulsed-modulated (pm) mode, and exposure time] were used. Exposure times were chosen to give the same total applied energy of 4 J for comparative purposes. Following laser irradiations, tissues were processed and stained with hematoxylin and eosin for mac-roscopic evaluation of ablation areas and total altered areas, and ablation efficiencies were calculated. Temperature of the nearby tissue at a distance of 1 mm from the fiber was measured, and rate of temperature change was calculated. A strong correlation between the rate of temperature change and ablation area was noted. Thermal effects increased with increasing power for both modes. The continuous-wave mode yielded higher ablation efficiencies than the pulse-modulated mode. Histological evaluation revealed a narrow vacuo-lization zone and negligible carbonization for higher-power values.

Recent advances in anti-infective drug discovery, Jun 13, 2024

Journal of Microbiological Methods

Photothermal ablation of liver tissue with 1940-nm thulium fiber laser: anex vivostudy on lamb liver

Journal of Biomedical Optics, 2016

Download

Photothermal ablation of liver tissue with 1940-nm thulium fiber laser: an ex vivo study on lamb liver

The purpose of this study was to investigate the ablation efficiency of 1940-nm thulium fiber las... more The purpose of this study was to investigate the ablation efficiency of 1940-nm thulium fiber laser on liver tissue, while utilizing a real-time measurement system to monitor the temperature rise in adjacent tissues. Thulium fiber laser was delivered to lamb liver tissue samples via 400-μm bare tip fiber in contact mode. Eight different laser parameter combinations [power, continuous-wave ðcwÞ∕pulsed-modulated (pm) mode, and exposure time] were used. Exposure times were chosen to give the same total applied energy of 4 J for comparative purposes. Following laser irradiations, tissues were processed and stained with hematoxylin and eosin for mac-roscopic evaluation of ablation areas and total altered areas, and ablation efficiencies were calculated. Temperature of the nearby tissue at a distance of 1 mm from the fiber was measured, and rate of temperature change was calculated. A strong correlation between the rate of temperature change and ablation area was noted. Thermal effects increased with increasing power for both modes. The continuous-wave mode yielded higher ablation efficiencies than the pulse-modulated mode. Histological evaluation revealed a narrow vacuo-lization zone and negligible carbonization for higher-power values.

Heba Alagha

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