NOL4
Jedarčani protein 4 je protein koji je kod ljudi kodiran genom NOL4.[5][6]
Dužina polipeptidnog lanca je 638 aminokiselina, sa molekulsom težinom od 71.357[7].
Aminokiselinska sekvenca
- Simboli
C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MESERDMYRQ | FQDWCLRTYG | DSGKTKTVTR | KKYERIVQLL | NGSESSSTDN | ||||
| AKFKFWVKSK | GFQLGQPDEV | RGGGGGAKQV | LYVPVKTTDG | VGVDEKLSLR | ||||
| RVAVVEDFFD | IIYSMHVETG | PNGEQIRKHA | GQKRTYKAIS | ESYAFLPREA | ||||
| VTRFLMSCSE | CQKRMHLNPD | GTDHKDNGKP | PTLVTSMIDY | NMPITMAYMK | ||||
| HMKLQLLNSQ | QDEDESSIES | DEFDMSDSTR | MSAVNSDLSS | NLEERMQSPQ | ||||
| NLHGQQDDDS | AAESFNGNET | LGHSSIASGG | THSREMGDSN | SDGKTGLEQD | ||||
| EQPLNLSDSP | LSAQLTSEYR | IDDHNSNGKN | KYKNLLISDL | KMEREARENG | ||||
| SKSPAHSYSS | YDSGKNESVD | RGAEDLSLNR | GDEDEDDHED | HDDSEKVNET | ||||
| DGVEAERLKA | FNMFVRLFVD | ENLDRMVPIS | KQPKEKIQAI | IDSCRRQFPE | ||||
| YQERARKRIR | TYLKSCRRMK | RSGFEMSRPI | PSHLTSAVAE | SILASACESE | ||||
| SRNAAKRMRL | ERQQDESAPA | DKQCKPEATQ | ATYSTSAVPG | SQDVLYINGN | ||||
| GTYSYHSYRG | LGGGLLNLND | ASSSGPTDLS | MKRQLATSSG | SSSSSNSRPQ | ||||
| LSPTEINAVR | QLVAGYRESA | AFLLRSADEL | ENLILQQN |
Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000101746 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041923 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Ueki N, Kondo M, Seki N, Yano K, Oda T, Masuho Y, Muramatsu M (Dec 1998). "NOLP: identification of a novel human nucleolar protein and determination of sequence requirements for its nucleolar localization". Biochem Biophys Res Commun. 252 (1): 97–102. doi:10.1006/bbrc.1998.9606. PMID 9813152.
- ^ "Entrez Gene: NOL4 nucleolar protein 4".
- ^ "UniProt, O94818". Pristupljeno 12. 9. 2017.
Dopunska literatura
[uredi | uredi izvor]- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Ueki N, Oda T, Kondo M, et al. (1999). "Selection system for genes encoding nuclear-targeted proteins". Nat. Biotechnol. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615. S2CID 20001769.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Tsang HT, Connell JW, Brown SE, et al. (2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941.