F9

F9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CFH, 1CFI, 1EDM, 1IXA, 1MGX, 1NL0, 1RFN, 2WPH, 2WPI, 2WPJ, 2WPK, 2WPL, 2WPM, 3KCG, 3LC3, 3LC5, 4YZU, 4Z0K, 4ZAE, 4WM0, 4WMA, 4WMI, 4WMK, 4WN2, 4WNH, 5EGM, 5JBC, 5JB9, 5JBB, 5JB8, 5JBA
Dynodwyr
Cyfenwau	F9, F9 p22, FIX, HEMB, P19, PTC, THPH8, coagulation factor IX, Blood coagulation factor IX, Christmas Factor
Dynodwyr allanol	OMIM: 300746 HomoloGene: 106 GeneCards: F9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • metal ion binding • GO:0070122 peptidase activity • serine-type peptidase activity • hydrolase activity • calcium ion binding • serine-type endopeptidase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • endoplasmic reticulum lumen • Cellbilen • Golgi lumen • extracellular exosome • extracellular region • extracellular space • collagen-containing extracellular matrix Prosesau biolegol • hemostasis • blood coagulation, intrinsic pathway • zymogen activation • endoplasmic reticulum to Golgi vesicle-mediated transport • signal peptide processing • blood coagulation, extrinsic pathway • peptidyl-glutamic acid carboxylation • proteolysis • blood coagulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2158	n/a
Ensembl	ENSG00000101981	n/a
UniProt	P00740	n/a
RefSeq (mRNA)	NM_000133 NM_001313913	n/a
RefSeq (protein)	NP_000124 NP_001300842	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn F9 yw F9 a elwir hefyd yn Coagulation factor IX (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq27.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F9.

• FIX
• P19
• PTC
• HEMB
• THPH8
• F9*p22

Llyfryddiaeth

• "Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations. ". Blood. 2017. PMID 28196793.
• "Usual and unusual mutations in a cohort of Belgian patients with hemophilia B. ". Thromb Res. 2017. PMID 27865967.
• "[Mutational Analysis of Hemophilia B in Russia: Molecular-Genetic Study]. ". Genetika. 2016. PMID 27529981.
• "Development and Optimization of AAV hFIX Particles by Transient Transfection in an iCELLis(®) Fixed-Bed Bioreactor. ". Hum Gene Ther Methods. 2016. PMID 27229773.
• "Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function.". PLoS Genet. 2016. PMID 27227676.