RXRG Dynodwyr Cyfenwau RXRG , NR2B3, RXRC, Retinoid X receptor gamma, RXR-gamma, RXRgammaDynodwyr allanol OMIM: 180247 HomoloGene: 21373 GeneCards: RXRG Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • zinc ion binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • DNA binding • metal ion binding • sequence-specific DNA binding • steroid hormone receptor activity • GO:0001948, GO:0016582 protein binding • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • retinoic acid receptor signaling pathway • GO:0009373 regulation of transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • protein homotetramerization • GO:0007329 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus • transcription, DNA-templated • steroid hormone mediated signaling pathway • transcription initiation from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[ 1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn RXRG yw RXRG a elwir hefyd yn Retinoid X receptor gamma (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.3.[ 2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RXRG.
"Association between retinoid-X receptor-gamma genetic polymorphisms and diabetic retinopathy. ". Genet Mol Res . 2011. PMID 22180072 .
"An RXR-γ Rx for white-matter damage. ". Nat Neurosci . 2011. PMID 21187846 .
"Expression proteomics predicts loss of RXR-γ during progression of epithelial ovarian cancer. ". PLoS One . 2013. PMID 23936423 .
"RXRγ gene variants are associated with HIV lipodystrophy. ". Pharmacogenet Genomics . 2013. PMID 23759678 .
"Adaptive evolution of the Retinoid X receptor in vertebrates. ". Genomics . 2012. PMID 22193333 .