If you try to style part of a syllable by putting a span around the characters you want to style, the overall shape of the syllable is broken.

Here are a number of examples:

1. Devanagari. If you put a span around the first two characters of the 3-character syllable स्तिठड (eg. in order to color or otherwise style it), the i vowel-sign no longer appears at the start of the word, but looks like it modifies the next character (ठ).
2. Gujarati. If you put a span around the ન્ડ two characters of the 3-character syllable ન્ડિ in ઇન્ડિય (eg. in order to color or otherwise style it), the i vowel-sign no longer appears at the start of the word, but looks like it modifies the next character (ય).
3. Bengali. If you put a span around the ব first character of the two character syllable বি in বিভাগের (eg. in order to color or otherwise style it), the vowel-sign no longer appears at the start of the word, but looks like incorrect inputting at the wrong place.
4. Tamil. If you put a span around the ம first character of the two character syllable மொ in மொழி (eg. in order to color or otherwise style it), the half part of o vowel-sign no longer appears at the start of the word, but looks like incorrect inputting at the wrong place.

Apparently this requirement is a bit difficult to cater to as it requires the knowledge to be transferred by the font to the rendering engine about which part of the glyph is attributed to which code-point in storage. However, if it can be achieved, nothing like it.