Journal of Muscle Research and Cell Motility, 2009
In addition to the highly specialized contractile apparatus, it is becoming increasingly clear th... more In addition to the highly specialized contractile apparatus, it is becoming increasingly clear that there is an extensive actin cytoskeleton which underpins a wide range of functions in striated muscle. Isoforms of cytoskeletal actin and actin-associated proteins (non-muscle myosins, cytoskeletal tropomyosins, and cytoskeletal α-actinins) have been detected in a number of regions of striated muscle: the sub-sarcolemmal costamere, the Z-disc and the T-tubule/sarcoplasmic reticulum membranes. As the only known function of these proteins is through association with actin filaments, their presence in striated muscles indicates that there are spatially and functionally distinct cytoskeletal actin filament systems in these tissues. These filaments are likely to have important roles in mechanical support, ion channel function, myofibrillogenenous and vesicle trafficking.
Numerous studies have pointed to a gap between the attitudes people express about the natural env... more Numerous studies have pointed to a gap between the attitudes people express about the natural environment and their subsequent behaviors toward that environment. Variables identified within these studies include: how significant others view behaviors related to the attitudes; demographic variables such as sex, age or education; self‐perceived ability to do the attitude‐related behavior; attitude strength; and personal relevance of the
Journal of Muscle Research and Cell Motility, 2009
In addition to the highly specialized contractile apparatus, it is becoming increasingly clear th... more In addition to the highly specialized contractile apparatus, it is becoming increasingly clear that there is an extensive actin cytoskeleton which underpins a wide range of functions in striated muscle. Isoforms of cytoskeletal actin and actin-associated proteins (non-muscle myosins, cytoskeletal tropomyosins, and cytoskeletal α-actinins) have been detected in a number of regions of striated muscle: the sub-sarcolemmal costamere, the Z-disc and the T-tubule/sarcoplasmic reticulum membranes. As the only known function of these proteins is through association with actin filaments, their presence in striated muscles indicates that there are spatially and functionally distinct cytoskeletal actin filament systems in these tissues. These filaments are likely to have important roles in mechanical support, ion channel function, myofibrillogenenous and vesicle trafficking.
Numerous studies have pointed to a gap between the attitudes people express about the natural env... more Numerous studies have pointed to a gap between the attitudes people express about the natural environment and their subsequent behaviors toward that environment. Variables identified within these studies include: how significant others view behaviors related to the attitudes; demographic variables such as sex, age or education; self‐perceived ability to do the attitude‐related behavior; attitude strength; and personal relevance of the
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Papers by Blake Hardeman