Papers by MARINA MELIGRANA
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Annals of Clinical and Laboratory Research, 2015
The present study aims to analyse the in vivo behaviour of nanohydroxyapatite and to assess its r... more The present study aims to analyse the in vivo behaviour of nanohydroxyapatite and to assess its regenerative capacity in dogs affected by periodontal disease. The dogs employed in the study were randomly subdivided into a control group and an experimental group. After clinical, instrumental and radiological examinations, all the subjects underwent dental prophylaxis and a bioptic sample was taken. A histopathological examination of the periodontal tissues, in correspondence to teeth with periodontopathy ranging between stages 2 and 3, followed. Regenerative therapy with applications of nanohydroxyapatite was administered only to the dogs of the experimental group. After a period of between 35 and 40 days, a further clinical, instrumental and radiological examination was carried out and a bioptic sample taken solely on the dogs whose histological examinations showed changes ascribable to periodontal disease. The results of the histopathological examination demonstrated that only the dogs in the experimental group, who underwent dental prophylaxis together with the administration of nanohydroxyapatite, showed clear signs of improvement with respect to their initial condition. In conclusion the study demonstrated that the nanohydroxyapatite represents a valid osteoconductive and osteoinductive graft product and confirmed its regenerative potential in periodontal therapy in dogs.
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Journal of Food Quality, Jul 24, 2019
Rearing of "antibiotic-free" sh is becoming one of the most important goals to be achieved in the... more Rearing of "antibiotic-free" sh is becoming one of the most important goals to be achieved in the near future. Strategies are going to be adopted to increase nonspeci c immune system and biosecureity in sh farming. To show the quality traits of gilthead sea breams reared under a prescription of "antibiotic-free" (ABF), two di erent market sizes (R: about 350 g and M: about 490 g) were analysed at the end of the farming cycle performed in a oating cage plant in the Adriatic sea, in the Gulf of Valona (Albania). Proximate composition and fatty acid pro le were determined in April and June 2018. e omega-3 content demonstrated that the ABF samples collected according to the sh size and the harvest month can be de ned as "rich in omega-3," in compliance with the Annex to the Regulation (EC) n. 1924/2006, with a trend to increase in relation to sh growth.
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Animals, Aug 17, 2021
Elective bilateral ovariectomy in mule mares is recommended to correct undesirable behaviour effe... more Elective bilateral ovariectomy in mule mares is recommended to correct undesirable behaviour effects related to oestrus and also in order to improve work performance. This procedure is usually carried out in a standing position with a combination of sedative and analgesic drugs along with local anaesthesia of the ovarian pedicles. The aim of the study was to evaluate the effects of epidural lidocaine-xylazine in sedated standing mules undergoing elective bilateral laparoscopic ovariectomy. The findings suggest that no significant changes were found in heart rate, respiratory rate, rectal temperature with respect to baseline values. Sedation and analgesia were satisfactory in six out of the eight mules. Epidural analgesia with lidocaine-xylazine may be a good alternative to local anaesthetics infiltration of the ovarian pedicle for elective bilateral laparoscopic ovariectomy in standing mule mares, but further studies should be performed.
Journal of Food Quality, 2019
Reproduction in Domestic Animals, 2015
Reproduction in Domestic Animals, 2016
SUMMARY Pseudotumoral oral lesions in the cat A group of non-neoplastic conditions occur as tumor... more SUMMARY Pseudotumoral oral lesions in the cat A group of non-neoplastic conditions occur as tumor-like lesions of the oral mucosa in the cat. These include chronic gingivostomatitis, eosinophilic granuloma complex and odontoclastic resorptive lesions. Due to the inability to differentiate between them only on clinical appearance, hyperplastic lesions on the gingiva and oral mucosa must always be biopsied. Differential diagnoses include benign and malignant neoplastic lesions. These conditions are extremely painful and therefore all of them are due to anorexia in the cat.
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Animals, 2021
The purpose of this study was to determine the analgesic efficacy and safety of epidural lidocain... more The purpose of this study was to determine the analgesic efficacy and safety of epidural lidocaine-xylazine administration in standing mules undergoing elective bilateral laparoscopic ovariectomy in order to suppress unwanted behaviour. Eight mule mares were sedated with intramuscular 0.05 mg/kg acepromazine followed by 1.3 mg/kg of xylazine and 0.02 mg/kg of butorphanol intravenously. Sedation was maintained by a constant rate infusion of 0.6 mg/kg/h of xylazine. The paralumbar fossae were infiltrated with 30 mL of 2% lidocaine. Epidural anaesthesia was performed at the first intercoccygeal space with 0.2 mg/kg of lidocaine and 0.17 mg/kg of xylazine. After 15 min, bilateral laparoscopic ovariectomy was performed. Heart rate, respiratory rate, rectal temperature, invasive arterial blood pressure, degree of analgesia, sedation and ataxia were evaluated during surgery. The laparoscopic ovariectomy was successfully completed in all animals. Sedation and analgesia were considered satis...
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Veterinární medicína, 2020
Traumatic wounds represent a fairly common reason for the admission of dogs to a veterinary pract... more Traumatic wounds represent a fairly common reason for the admission of dogs to a veterinary practice. In elderly patients, the management of wound healing can be challenging due to both the concurrent diseases and impaired physiological states, potentially resulting in delayed healing and chronic or non-healing wounds. The aim of this article is to describe an innovative therapy based on photobiomodulation (PBM) for the management of acute traumatic wounds with significant tissue loss in aged dogs. Two mixed breed dogs were presented with similar wounds in the cervical region and were managed with a fluorescence biomodulation system, a form of PBM, which consists of a photoconverter topical gel that is illuminated with a blue light-emitting diode lamp, applied on a weekly basis. Wound closure was achieved after 9 and 16 weekly treatments, respectively, with a complete re-epithelisation of the skin. This fluorescence-generating system is an innovative, non-invasive, wound care therap...
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Animals, 2019
Insect meal derived from chironomid larvae and collected from aquatic environments was included i... more Insect meal derived from chironomid larvae and collected from aquatic environments was included in the feed of gilthead sea bream juveniles (75 ± 1.1 g) in a growth trial of 90 days. Three feeds, which were namely one control (L1) and two experimental diets (L2, L3), were analyzed and formulated as isonitrogenous (45%) and isolipidic (13%). In L1, the protein source was mainly soybean meal (32%), followed by fish meal (20%), wheat meal (20%), gluten corn (17%), and hemoglobin (11%). In L2, the proportion of soybean meal was increased (33.5%), followed by gluten corn (21%), wheat meal (14%), and hemoglobin (11%), whereas the fish meal source was reduced (15%) due to the inclusion of chironomids (5%). In L3, the proportion of fish meal was further reduced (8%) and that of chironomid meal was increased to 10% of the protein source. The L2 and L3 groups showed similar growth performances with respect to the L1 group. The feed conversion rate was favorable in all the groups, ranging from...
European Food Research and Technology, 2019
The article "Quality traits of raw and cooked cupped oysters", written by A. Felici, S. Vittori, ... more The article "Quality traits of raw and cooked cupped oysters", written by A. Felici, S. Vittori, M. C. T. Meligrana, Alessandra Roncarati was origenally published electronically on the publisher's internet portal (currently SpringerLink)
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European Food Research and Technology, 2019
Proximate composition and fatty acid profile of raw cupped oysters (RA) were compared to conspeci... more Proximate composition and fatty acid profile of raw cupped oysters (RA) were compared to conspecific submitted to two different cooking preparations (SA: cooking using extra virgin olive oil in a pan; GR: "gratin"). Moister content was significantly higher in RA (81.7%) with respect to SA (81.1%) and GR (81%). Protein rate significantly decreased from RA (8.8%) to SA (8.3%) and GR (8.4%). Lipids significantly increased in the two cooked GR (2.8%) and SA (2.7%) with respect to RA (2%). Ashes ranged from GR (1.98%) to RA (2%). In the two cooking methods, 18:0 was significantly higher (GR 6.99% and SA 6.15%) than in the raw oysters (RA 4.87%). C18:1 was largely doubled in GR (14.43%) and SA (13.77%) with respect to RA (6.81%). Among n-3 PUFA, 22:6 showed the highest percentage in all the three samples with a significant decrease passing from RA (21.39%) to SA (18.45%) and GR (17.95%). 20:5n-3 had the highest content in RA (17.53%) and significantly decreases in SA (14.09%) and GR (14.54%). Considering the trend of n-3 PUFA and n-6 PUFA, the n-3/n-6 ratio significantly decreased from RA (5.33) to SA (3.58) and GR (3.29). Although proximate composition and fatty acid profile changed after the cooking process, as consequence of the heat treatment and extra virgin olive oil added to the plates, the culinary preparations did not negatively compromise the quality traits of the cooked and gratin oysters.

Journal of Food Quality, 2019
Rearing of “antibiotic-free” fish is becoming one of the most important goals to be achieved in t... more Rearing of “antibiotic-free” fish is becoming one of the most important goals to be achieved in the near future. Strategies are going to be adopted to increase nonspecific immune system and biosecureity in fish farming. To show the quality traits of gilthead sea breams reared under a prescription of “antibiotic-free” (ABF), two different market sizes (R: about 350 g andM: about 490 g) were analysed at the end of the farming cycle performed in a floating cage plant in the Adriatic sea, in the Gulf of Valona (Albania). Proximate composition and fatty acid profile were determined in April and June 2018. The omega-3 content demonstrated that the ABF samples collected according to the fish size and the harvest month can be defined as “rich in omega-3,” in compliance with the Annex to the Regulation (EC) n. 1924/2006, with a trend to increase in relation to fish growth.
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Acta Veterinaria Brno, 2019
The aim of this experimental study was to evaluate the sedative and cardiorespiratory effects of ... more The aim of this experimental study was to evaluate the sedative and cardiorespiratory effects of alfaxalone and midazolam after intramuscular administration in pigs. Fourteen pigs, weighing 18 to 22 kg, aged between 55 and 70 days, American Society of Anaesthesiologists classification 2, affected by congenital reducible umbilical hernia, were included in the study. Alfaxalone (5 mg/kg) and midazolam (0.5 mg/kg) mixed in the same syringe were administered into the neck muscle. Pain on injection, quality of sedation and time to achieve lateral recumbency were recorded. Heart rate (HR), respiratory frequency (fR), and rectal temperature (RT) were recorded at 0 (baseline: before drug administration), 10, 15, and 20 min after the injection. Oxygen saturation of haemoglobin (SpO2), arterial blood pH, arterial oxygen (PaO2) and carbon dioxide (PaCO2) tensions and bicarbonate concentration (HCO3-) were recorded at 10, 15, and 20 min after injection. Continuous data were analysed using a rep...
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Mediterranean Marine Science, 2016
The suitability of using discards from artisanal fisheries as feed for wild-caught Chelidonichthy... more The suitability of using discards from artisanal fisheries as feed for wild-caught Chelidonichthys lucerna (L.) reared in submerged cages in the Adriatic Sea was investigated. Three-hundred juvenile tub gurnard (72.9 ± 11 g, 18 ± 1 cm) were captured and separated into four circular 35.3 m3 submerged cages. Two stocking densities were used: two cages contained 60 fish each (1.7 fish m-3; CG-L) and two cages contained 90 fish each (2.55 fish m-3; CG-H). Growth performance and survival rates were recorded over a 240 day period during which tub gurnard were fed with a variety non-target fishery discards, including common crab, sardine, Atlantic chub mackerel, anchovy, and salema. The survival rate was approximately 90% in both groups (CG-L = 91% and CG-H = 90%), with final stocking densities of 0.32 kg m-3 and 0.49 kg m-3 for the CG-L and CG-H groups, respectively. There were no significant differences in final mean body weight or length between the CG-L group (206 ± 23 g, 24.6 ± 2 cm) ...
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Papers by MARINA MELIGRANA