Just had what might be the highest damage run of all time.  Got a garbage collector turn 1 to clear out the civilians, then w/in a couple more turns got a cloning chamber & aegis - aegis kept the cloning chamber around to keep cloning more aegis.... when I had enough aegises I used an IA to remove the cloning chamber.  Then got a secret chest that never went away thanks to the aegises, and a time bomb to keep damage low so I can farm a lot.  Also got Berserker + Hypercharger + Green Hands to trigger w/ low health (only once, but that was enough).  Eventually the time bomb did end up getting into an unprotected corner & blew itself up & ended my farming, but by then I had big numbers.... too big to fit on screen ;-)