Abstract
The hypothesis that motor imagery and actual movement involve overlapping neural structures in the central nervous system is supported by multiple lines of evidence. The aim of this study was to examine the modulation of corticomotor excitability during two types of strategies for motor imagery: Kinesthetic Motor Imagery (KMI) and Visual Motor Imagery (VMI) in a phasic thumb movement task. Transcranial magnetic stimulation (TMS) was applied over the contralateral motor cortex (M1) to elicit motor evoked potentials (MEPs) in the dominant abductor pollicis brevis (APB) and abductor digiti minimi (ADM). In a separate experiment, transcutaneous electrical stimuli were delivered to the median nerve at the dominant wrist, to elicit F-waves from APB. Imagined task performance was paced with a 1 Hz auditory metronome, and stimuli were delivered either 50 ms before (ON phase), or 450 ms after (OFF phase), the metronome beeps. Recordings were also made during two control conditions: Rest, and a Visual Static Imagery (VSI) condition. Significant MEP amplitude facilitation occurred only in APB, and only during the ON phase of KMI. F-wave persistence and amplitude were unaffected by imagery. These results demonstrate that kinesthetic, but not visual, motor imagery modulates corticomotor excitability, primarily at the supraspinal level. These findings have implications for the definition of motor imagery, and for its therapeutic applications.
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References
Barreca S, Wolf SL, Fasoli S, Bohannon R (2003) Treatment interventions for the paretic upper limb of stroke survivors: a critical review. Neurorehabil Neural Repair 17:220–226
Beisteiner R, Hollinger P, Lindinger G, Lang W, Berthoz A (1995) Mental representations of movements. Brain potentials associated with imagination of hand movements. Electroencephalogr Clin Neurophysiol 96:183–193
Bonnet M, Decety J, Jeannerod M, Requin J (1997) Mental simulation of an action modulates the excitability of spinal reflex pathways in man. Cognitive Brain Research 5:221–228
Caldara R, Deiber MP, Andrey C, Michel CM, Thut G, Hauert C-A (2004) Actual and mental motor preparation and execution: a spatiotemporal ERP study. Exp Brain Res 159:389–399
Clark S, Tremblay F, Ste-Marie D (2003) Differential modulation of corticospinal excitability during observation, mental imagery and imitation of hand actions. Neuropsychologia 42:105–112
Decety J, Perani D, Jeannerod M, Bettinardi V, Tadary B, Woods R, Mazziotta JC, Fazio F (1994) Mapping motor representations with positron emission tomography. Nature 371:600–602
Dechent P, Merboldt K-D, Frahm J (2004) Is the human primary motor cortex involved in motor imagery? Cognitive Brain Res 19:138–144
Deiber MP, Ibanez V, Honda M, Sadato N, Raman R, Hallett M (1998) Cerebral processes related to visuomotor imagery and generation of simple finger movements studied with positron emission tomography. NeuroImage 7:73–85
Driskell JE, Copper C, Moran A (1994) Does mental practice enhance performance? J Appl Psychol 79:481–492
Ehrsson HH, Geyer S, Naito E (2003) Imagery of voluntary movement of fingers, toes, and tongue activates corresponding body-part-specific motor representations. J Neurophysiol 90:3304–3316
Facchini S, Muellbacher W, Battaglia F, Boroojerdi B, Hallett M (2002) Focal enhancement of motor cortex excitability during motor imagery: a transcranial magnetic stimulation study. Acta Neurol Scand 105:146–151
Fadiga L, Buccino G, Craighero L, Fogassi L, Gallese V, Pavesi G (1999) Corticospinal excitability is specifically modulated by motor imagery: a magnetic stimulation study. Neuropsychologia 37:147–158
Feltz DL, Landers DM (1983) The effects of mental practice on motor skill learning and performance. J Sport Psychol 5:25–57
Fery YA (2003) Differentiating visual and kinesthetic imagery in mental practice. Can J Exp Psychol 57:1–10
Frith C, Dolan RJ (1997) Brain mechanisms associated with top-down processes in perception. Phil Trans R S London Ser. B: Biol Sci 352:1221–1230
Gerardin E, Sirigu A, Lehericy S, Poline JB, Gaymard B, Marsault C, Agid Y, Le Bihan D (2000) Partially overlapping neural networks for real and imagined hand movements. Cereb Cortex 10:1093–1104
Hall CR, Martin KA (1997) Measuring movement imagery abilities: a revision of the movement imagery questionnaire. J Mental Imagery 21:143–154
Hall C, Pongrac J, Buckholz E (1985) The measurement of imagery ability. Human Movement Sci 4:107–118
Hanakawa T, Immisch I, Toma K, Dimyan M, van Gelderen P, Hallett M (2003) Functional properties of brain areas associated with motor execution and imagery. J Neurophysiol 89:989–1002
Hashimoto R, Rothwell JC (1999) Dynamic changes in corticospinal excitability during motor imagery. Exp Brain Res 125:75–81
Jackson PL, Lafleur MF, Malouin F, Richards CL, Doyon J (2003) Functional cerebral reorganization following motor sequence learning through mental practice with motor imagery. NeuroImage 20:1171–1180
Jancke L, Kleinschmidt A, Mirzazade S, Shah NJ, Freund HJ (2001) The role of the inferior parietal cortex in linking the tactile perception and manual construction of object shapes. Cereb Cortex 11:114–121
Kasai T, Kawai S, Kawanishi M, Yahagi S (1997) Evidence for facilitation of motor evoked potentials (MEPs) induced by motor imagery. Brain Research 744:147–150
Kiers L, Fernando B, Tomkins D (1997) Facilitatory effect of thinking about movement on magnetic motor-evoked potentials. Electroencephal Clin Neurophysiol 105:262–268
Kuhtz-Buschbeck JP, Mahnkopf C, Holzknecht C, Siebner H, Ulmer S, Jansen O (2003) Effector-independent representations of simple and complex imagined finger movements: a combined fMRI and TMS study. Euro J Neurosci 18:3375–3387
Li S, Kamper DG, Stevens JA, Rymer WZ (2004) The effect of motor imagery on spinal segmental excitability. J Neurosci 24:9674–9680
Lotze M, Montoya P, Erb M, Hulsmann E, Flor H, Klose U, Birbaumer N, Grodd W (1999) Activation of cortical and cerebellar motor areas during executed and imagined hand movements: an fMRI study. J Cog Neurosci 11:491–501
Lotze M, Scheler G, Tan HR, Braun C, Birbaumer N (2003) The musician’s brain: functional imaging of amateurs and professionals during performance and imagery. Neuroimage 20:1817–1829
Malouin F, Belleville S, Richards CL, Desrosiers J, Doyon J (2004) Working memory and mental practice outcomes after stroke. Arch Phys Med Rehabil 85:177–183
Mattia D, Mattiocco M, Timperi A, Salinari S, Marciani MG, Babiloni F, Febo C (2004) Estimation of cortical activity from noninvasive high-resolution EEG recordings. Int Cong Ser 1270:245–248
Meister IG, Krings T, Foltys H, Boroojerdi B, Muller M, Topper R, Thron A (2004) Playing piano in the mind – an fMRI study on music imagery and performance in pianists. Brain Res Cogn Brain Res 19:219–228
Miall RC, Wolpert DM (1996) Forward models for physiological motor control. Neural Netw 9:1265–1279
Nair DG, Purcott KL, Fuchs A, Steinberg F, Kelso JA (2003) Cortical and cerebellar activity of the human brain during imagined and executed unimanual and bimanual action sequences: a functional MRI study. Brain Res Cogn Brain Res 15:250–260
Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9:97–113
Page SJ, Levine P, Sisto S, Johnston MV (2001) A randomized efficacy and feasibility study of imagery in acute stroke. Clin Rehabil 15:233–240
Pascual-Leone A, Dang N, Cohen LG, Brasil-Neto JP, Cammarota A, Hallett M (1995) Modulation of muscle responses evoked by transcranial magnetic stimulation during the acquisition of new fine motor skills. J Neurophysiol 74:1037–1045
Pfurtscheller G, Neuper C (1997) Motor imagery activates primary sensorimotor area in humans. Neurosci Lett 239:65–68
Porro CA, Francescato MP, Cettolo V, Diamond ME, Baraldi P, Zuiani C, Bazzocchi M, di Prampero PE (1996) Primary motor and sensory cortex activation during motor performance and motor imagery: a functional magnetic resonance imaging study. J Neurosci 16:7688–7698
Porro CA, Cettolo V, Francescato MP, Baraldi P (2000) Ipsilateral involvement of primary motor cortex during motor imagery. Euro J Neurosci 12:3059–3063
Romero DH, Lacourse MG, Lawrence KE, Schandler S, Cohen MJ (2000) Event-related potentials as a function of movement parameter variations during motor imagery and isometric action. Behav Brain Res 117:83–96
Ross JS, Tkach J, Ruggieri PM, Lieber M, Lapresto E (2003) The mind’s eye: functional MR imaging evaluation of golf motor imagery. AJNR Am J Neuroradiol 24:1036–1044
Rossi S, Pasqualetti P, Tecchio F, Pauri F, Rossini PM (1998) Corticospinal excitability modulation during mental simulation of wrist movements in human subjects. Neurosci Lett 243:147–151
Rossini PM, Rossini S, Pasqualetti P, Tecchio F (1999) Corticospinal excitability modulation to hand muscles during movement imagery. Cereb Cortex 9:161–167
Roth M, Decety J, Raybaudi M, Massarelli R, Delon-Martin C, Segebarth C, Morand S, Gemignani A, Decorps M, Jeannerod M (1996) Possible involvement of primary motor cortex in mentally simulated movement: a functional magnetic resonance imaging study. Neuroreport 7:1280–1284
Ruby P, Decety J (2001) Effect of subjective perspective taking during simulation of action: a PET investigation of agency. Nat Neurosci 4:546–550
Schnitzler A, Salenius S, Salmelin R, Jousmaki V, Hari R (1997) Involvement of primary motor cortex in motor imagery: a neuromagnetic study. Neuroimage 6:201–208
Sethi RK, Thompson LL (1989) The Electromyographer’s Handbook. Little Brown, Boston, MA
Solodkin A, Hlustik P, Chen EE, Small SL (2004) Fine modulation in network activation during motor execution and motor imagery. Cereb Cortex 14:1246–1255
Spiegler A, Graimann B, Pfurtscheller G (2004) Phase coupling between different motor areas during tongue-movement imagery. Neurosci Lett 369:50–54
Stephan KM, Fink GR, Passingham RE, Silbersweig D, Ceballos-Baumann AO, Frith CD, Frackowiak RSJ (1995) Functional anatomy of the mental representation of upper extremity movements in healthy subjects. J Neurophysiol 73:373–386
Stevens JA, Stoykov ME (2003) Using motor imagery in the rehabilitation of hemiparesis. Arch Phys Med Rehabil 84:1090–1092
Stinear CM, Byblow WD (2003) Motor imagery of phasic thumb abduction temporally and spatially modulates corticospinal excitability. Clin Neurophysiol 114:909–914
Stinear CM, Byblow WD (2004) Modulation of corticospinal excitability and intracortical inhibition during motor imagery is task-dependent. Exp Brain Res 157:351–358
Yahagi S, Kasai T (1998) Facilitation of motor evoked potentials (MEPs) in first dorsal interosseous (FDI) muscle is dependent on different motor images. Electroencephal Clin Neurophysiol 109:409–417
Yahagi S, Shimura K, Kasai T (1996) An increase in cortical excitability with no change in spinal excitability during motor imagery. Percep Motor Skills 83:288–290
Yoo E, Park E, Chung B (2001) Mental practice effect on line-tracing accuracy in persons with hemiparetic stroke: a preliminary study. Arch Phys Med Rehabil 82:1213–1218
Acknowledgements
The authors would like to thank Craig Hall for helpful comments related to the MIQ-R, and Cheryl Murphy and Melanie Fleming for their assistance in data collection and analysis. Support for the present study was provided through grants from the Research Council of K.U. Leuven, Belgium (Contract No. OT/03/61), the Research Programme of the Fund for Scientific Research Flanders (FWO-Vlaanderen# G.0460.04 and G.0245.05), and the Auckland Medical Research Foundation (81475).
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Stinear, C.M., Byblow, W.D., Steyvers, M. et al. Kinesthetic, but not visual, motor imagery modulates corticomotor excitability. Exp Brain Res 168, 157–164 (2006). https://doi.org/10.1007/s00221-005-0078-y
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DOI: https://doi.org/10.1007/s00221-005-0078-y