Content-Length: 43891 | pFad | https://pubmed.ncbi.nlm.nih.gov/23445833

ar Increased risk for Campylobacter jejuni and C. coli infection of pet origen in dog owners and evidence for genetic association between strains causing infection in humans and their pets

Increased risk for Campylobacter jejuni and C. coli infection of pet origen in dog owners and evidence for genetic association between strains causing infection in humans and their pets

Epidemiol Infect. 2013 Dec;141(12):2526-35. doi: 10.1017/S0950268813000356. Epub 2013 Feb 28.

Abstract

We compared Campylobacter jejuni/coli multilocus sequence types (STs) from pets (dogs/cats) and their owners and investigated risk factors for pet-associated human campylobacteriosis using a combined source-attribution and case-control analysis. In total, 132/687 pet stools were Campylobacter-positive, resulting in 499 strains isolated (320 C. upsaliensis/helveticus, 100 C. jejuni, 33 C. hyointestinalis/fetus, 10 C. lari, 4 C. coli, 32 unidentified). There were 737 human and 104 pet C. jejuni/coli strains assigned to 154 and 49 STs, respectively. Dog, particularly puppy, owners were at increased risk of infection with pet-associated STs. In 2/68 cases vs. 0.134/68 expected by chance, a pet and its owner were infected with an identical ST (ST45, ST658). Although common sources of infection and directionality of transmission between pets and humans were unknown, dog ownership significantly increased the risk for pet-associated human C. jejuni/coli infection and isolation of identical strains in humans and their pets occurred significantly more often than expected.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Campylobacter Infections / microbiology*
  • Campylobacter Infections / transmission*
  • Campylobacter coli / classification*
  • Campylobacter coli / genetics
  • Campylobacter coli / isolation & purification
  • Campylobacter jejuni / classification*
  • Campylobacter jejuni / genetics
  • Campylobacter jejuni / isolation & purification
  • Cats
  • Child
  • Child, Preschool
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Dogs
  • Female
  • Genotype
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Multilocus Sequence Typing
  • Pets
  • Risk Assessment
  • Young Adult
  • Zoonoses / microbiology*
  • Zoonoses / transmission*

Substances

  • DNA, Bacterial








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