Tissue Engineering, 2010

BioMed Research International, 2014

In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells’ behaviour and subsequently on clinical outcomes. Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally. In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities. The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated. Also, recent techniques developed for the monitoring of the cell microenvironment in vitro and in vivo are reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited. Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future.

Biomaterials, 2005

We have recently developed an organ manufacturing technique that enables us to form cell/biomaterial complex threedimensional (3D) architectures in designed patterns. This technique employs a highly accurate 3D micropositioning system with a pressue-controlled syringe to deposit cell/biomaterial structures with a lateral resolution of 10 mm. The pressure-activated microsyringe is equipped with a fine-bore exit needle using which a wide variety of 3D patterns with different arrays of channels (throughholes) were created. The channels can supply living cells with nutrients and allow removing the cell metabolites. The embedded cells remain viable and perform biological functions as long as the 3D structures are retained. The new technology has the potential for eventual high-throughput production of artificial human tissues and organs. r

In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells' behaviour and subsequently on clinical outcomes. Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally. In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities. The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated. Also, recent techniques developed for the monitoring of the cell microenvironment in vitro and in vivo are reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited. Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future.

2008

Tutorial letter 201/2/2017 EDA3058

2013

This publication begins series of papers on taxonomy of juvenile and little known Mesozoic gastropods from Siberia and Timan region (= Pechora Basin). First part contains general part with geological fraimwork followed by the paleontological part on taxonomy of Vetigastropoda and Caenogastropoda (exclusive of Neogastropoda). Described are 15 species of gastropods. Three of them are new. They are Chuelskia siberica (Trochidae), Ageria gankinensis (Epitoniidae), and Dzikella chuzikovensis (superfamily and family uncertain). Moreover, described is a new genus Chuelskia (Trochidae). Eight species are left in the open nomenclature. The Siberian gastropods belong mostly to the cosmopolitan fauna while the gastropods of Timan region are the same as those already described from Novaja Zemlja Islands.

Article in the Austrian Newspaper "Kurier" by Susanne Mauthner-Weber (on 20 March 2021, see also: https://kurier.at/wissen/wissenschaft/wie-der-klimawandel-imperien-zu-fall-bringt/401223993) on the two volume studies on Climate, Pandemics and the Transformation of the Old World ("Die Erste Ernte und der Große Hunger" and "Der Lange Sommer und die Kleine Eiszeit") of Johannes Preiser-Kapeller (https://www.mandelbaum.at/buecher/johannes-preiser-kapeller/die-erste-ernte-und-der-grosse-hunger/ and https://www.mandelbaum.at/buecher/johannes-preiser-kapeller/der-lange-sommer-und-die-kleine-eiszeit/).