mTOR inhibition enhances synaptic and mitochondrial function in Alzheimer's disease in an APOE genotype-dependent manner.
J Cereb Blood Flow Metab.
2024 Oct;44(10):1745-1758. doi: 10.1177/0271678X241261942. Epub 2024 Jun 16. PubMed PMID:
38879800; PubMed Central PMCID:
PMC11494852.
The Uncoupling Effect of 17β-Estradiol Underlies the Resilience of Female-Derived Mitochondria to Damage after Experimental TBI.
Life (Basel).
2024 Jul 30;14(8). doi: 10.3390/life14080961. PubMed PMID:
39202703; PubMed Central PMCID:
PMC11355196.
The role of mitochondrial uncoupling in the regulation of mitostasis after traumatic brain injury.
Neurochem Int.
2024 Mar;174:105680. doi: 10.1016/j.neuint.2024.105680. Epub 2024 Feb 3. PubMed PMID:
38311216; PubMed Central PMCID:
PMC10922998.
Effects of Low-Level Blast on Neurovascular Health and Cerebral Blood Flow: Current Findings and Future Opportunities in Neuroimaging.
Int J Mol Sci.
2024 Jan 4;25(1). doi: 10.3390/ijms25010642. Review. PubMed PMID:
38203813; PubMed Central PMCID:
PMC10779081.
Mitochondrial Dysfunction After Repeated Mild Blast Traumatic Brain Injury Is Attenuated by a Mild Mitochondrial Uncoupling Prodrug.
J Neurotrauma.
2023 Nov;40(21-22):2396-2409. doi: 10.1089/neu.2023.0102. Epub 2023 Aug 25. PubMed PMID:
37476976; PubMed Central PMCID:
PMC10653072.
Characterizing Sex Differences in Mitochondrial Dysfunction After Severe Traumatic Brain Injury in Mice.
Neurotrauma Rep.
2023;4(1):627-642. doi: 10.1089/neur.2023.0046. eCollection 2023. PubMed PMID:
37752924; PubMed Central PMCID:
PMC10518693.
LRP1 Deficiency Promotes Mitostasis in Response to Oxidative Stress: Implications for Mitochondrial Targeting after Traumatic Brain Injury.
Cells.
2023 May 22;12(10). doi: 10.3390/cells12101445. PubMed PMID:
37408279; PubMed Central PMCID:
PMC10217498.
Pioglitazone restores mitochondrial function but does not spare cortical tissue following mild brain contusion.
Brain Commun.
2023;5(2):fcad032. doi: 10.1093/braincomms/fcad032. eCollection 2023. PubMed PMID:
36879917; PubMed Central PMCID:
PMC9985333.
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma.
Mitochondrion.
2023 Jan;68:10-14. doi: 10.1016/j.mito.2022.11.001. Epub 2022 Nov 9. Review. PubMed PMID:
36371072; PubMed Central PMCID:
PMC9805511.
Resilience of females to acute blood-brain barrier damage and anxiety behavior following mild blast traumatic brain injury.
Acta Neuropathol Commun.
2022 Jun 27;10(1):93. doi: 10.1186/s40478-022-01395-8. PubMed PMID:
35761393; PubMed Central PMCID:
PMC9235199.
Tissue factor release following traumatic brain injury drives thrombin generation.
Res Pract Thromb Haemost.
2022 May;6(4):e12734. doi: 10.1002/rth2.12734. eCollection 2022 May. PubMed PMID:
35702585; PubMed Central PMCID:
PMC9175244.
Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury.
Brain.
2021 Dec 31;144(12):3788-3807. doi: 10.1093/brain/awab341. PubMed PMID:
34972207; PubMed Central PMCID:
PMC8719838.
Differential Leukocyte and Platelet Profiles in Distinct Models of Traumatic Brain Injury.
Cells.
2021 Feb 26;10(3). doi: 10.3390/cells10030500. PubMed PMID:
33652745; PubMed Central PMCID:
PMC7996744.
Links between thrombosis and inflammation in traumatic brain injury.
Thromb Res.
2021 Feb;198:62-71. doi: 10.1016/j.thromres.2020.10.041. Epub 2020 Nov 25. Review. PubMed PMID:
33290884; PubMed Central PMCID:
PMC7867616.
Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology.
Cells.
2021 Jan 20;10(2). doi: 10.3390/cells10020199. PubMed PMID:
33498273; PubMed Central PMCID:
PMC7909250.
Mitochondrial drug delivery systems: therapeutic application for clinical bioenergetics in neurodegenerative disease.
In:
Ostojic S, editor.
Clinical Bioenergetics
[Internet]
London, UK: Academic Press; 2021. Chapter 17; p.385-409.
Available from: https://www.sciencedirect.com/science/article/pii/B9780128196212000176.
Formoterol, a β(2)-adrenoreceptor agonist, induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury.
Neurobiol Dis.
2020 Jul;140:104866. doi: 10.1016/j.nbd.2020.104866. Epub 2020 Apr 11. PubMed PMID:
32289370.
Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: New mechanism of pioglitazone following traumatic brain injury.
Exp Neurol.
2020 May;327:113243. doi: 10.1016/j.expneurol.2020.113243. Epub 2020 Feb 10. PubMed PMID:
32057797; PubMed Central PMCID:
PMC7089834.
Novel imaging biomarkers for mapping the impact of mild mitochondrial uncoupling in the outer retina in vivo.
PLoS One.
2020;15(1):e0226840. doi: 10.1371/journal.pone.0226840. eCollection 2020. PubMed PMID:
31923239; PubMed Central PMCID:
PMC6953833.
An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors.
J Med Chem.
2019 Dec 26;62(24):11348-11358. doi: 10.1021/acs.jmedchem.9b01685. Epub 2019 Dec 16. PubMed PMID:
31774672; PubMed Central PMCID:
PMC7560992.
Fractionated mitochondrial magnetic separation for isolation of synaptic mitochondria from brain tissue.
Sci Rep.
2019 Jul 4;9(1):9656. doi: 10.1038/s41598-019-45568-3. PubMed PMID:
31273236; PubMed Central PMCID:
PMC6609636.
Experimental Designs for Repeated Mild Traumatic Brain Injury: Challenges and Considerations.
J Neurotrauma.
2019 Apr 15;36(8):1203-1221. doi: 10.1089/neu.2018.6096. Epub 2018 Nov 22. Review. PubMed PMID:
30351225; PubMed Central PMCID:
PMC6479246.
Acute Mitochondrial Impairment Underlies Prolonged Cellular Dysfunction after Repeated Mild Traumatic Brain Injuries.
J Neurotrauma.
2019 Apr 15;36(8):1252-1263. doi: 10.1089/neu.2018.5990. Epub 2018 Dec 20. PubMed PMID:
30417732; PubMed Central PMCID:
PMC7207062.
Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice.
J Neurosci Res.
2018 Oct;96(10):1677-1688. doi: 10.1002/jnr.24271. Epub 2018 Jul 31. PubMed PMID:
30063076; PubMed Central PMCID:
PMC6129401.
Hemostatic nanoparticles increase survival, mitigate neuropathology and alleviate anxiety in a rodent blast trauma model.
Sci Rep.
2018 Jul 13;8(1):10622. doi: 10.1038/s41598-018-28848-2. PubMed PMID:
30006635; PubMed Central PMCID:
PMC6045585.
Fujikawa DG, editor.
Mitochondrial Damage in Traumatic CNS Injury: Acute Neuronal Injury
2nd ed. .: Springer; 2018.
Distinguishing the Unique Neuropathological Profile of Blast Polytrauma.
Oxid Med Cell Longev.
2017;2017:5175249. doi: 10.1155/2017/5175249. Epub 2017 Mar 23. PubMed PMID:
28424745; PubMed Central PMCID:
PMC5382305.
Cellular Mechanisms and Behavioral Outcomes in Blast-Induced Neurotrauma: Comparing Experimental Setups.
Methods Mol Biol.
2016;1462:119-38. doi: 10.1007/978-1-4939-3816-2_8. PubMed PMID:
27604716.
Enduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury.
Sci Rep.
2015 Nov 5;5:15075. doi: 10.1038/srep15075. PubMed PMID:
26537106; PubMed Central PMCID:
PMC4633584.
Subacute Oxidative Stress and Glial Reactivity in the Amygdala are Associated with Increased Anxiety Following Blast Neurotrauma.
Shock.
2015 Aug;44 Suppl 1:71-8. doi: 10.1097/SHK.0000000000000311. PubMed PMID:
25521536.
Steroid-Loaded Hemostatic Nanoparticles Combat Lung Injury after Blast Trauma.
ACS Macro Lett.
2015 Apr 21;4(4):387-391. doi: 10.1021/acsmacrolett.5b00061. Epub 2015 Mar 23. PubMed PMID:
27668129; PubMed Central PMCID:
PMC5033257.
Blast Induced Neurotrauma Leads To Changes In The Epigenome.
Biomed Sci Instrum.
2015;51:423-30. PubMed PMID:
25996748.
Examining lethality risk for rodent studies of primary blast lung injury.
Biomed Sci Instrum.
2014;50:92-9. PubMed PMID:
25405409; PubMed Central PMCID:
PMC4591070.
A new model for mild blast injury utilizing Drosophila melanogaster - biomed 2013.
Biomed Sci Instrum.
2013;49:134-40. PubMed PMID:
23686192.
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