The Energy Balance and Body Composition Core (EBC) provides the equipment for measurement of lean/fat mass and whole body metabolism in mice.  Because the primary focus of the COCVD is to identify mechanisms linking obesity to cardiovascular disease, it is imperative to obtain a sensitive, reproducible quantitative analysis of these measures of adiposity and metabolism. The Echo MRI is utilized for non-invasive quantitative assessment of lean and fat mass.  The Sable Promethion Calorimeter indirectly measures oxygen consumption (RER), food and water intake, and physical activity in mice.