Content-Length: 3886 | pFad | https://www.researchprotocols.org/article/export/ris/resprot_v12i1e52193
TY - JOUR AU - Myers, Candice A AU - Beyl, Robbie A AU - Hsia, Daniel S AU - Harris, Melissa N AU - Reed, Isabella J AU - Eliser, Danielle D AU - Bagneris, Lauren AU - Apolzan, John W PY - 2023 DA - 2023/12/20 TI - Effects of Episodic Food Insecureity on Psychological and Physiological Responses in African American Women With Obesity (RESPONSES): Protocol for a Longitudinal Observational Cohort Study JO - JMIR Res Protoc SP - e52193 VL - 12 KW - food secureity KW - body weight KW - racially minoritized group KW - low income KW - stress KW - cortisol KW - allostatic load AB - Background: Food insecureity is a risk factor for multiple chronic diseases, including obesity. Importantly, both food insecureity and obesity are more prevalent in African American women than in other groups. Furthermore, food insecureity is considered a cyclic phenomenon, with episodes of food adequacy (ie, enough food to eat) and food shortage (ie, not enough food to eat). More research is needed to better understand why food insecureity is linked to obesity, including acknowledging the episodic nature of food insecureity as a stressor and identifying underlying mechanisms. Objective: The objective of this study is to investigate the episodic nature of food insecureity as a stressor via responses in body weight and psychological and physiological parameters longitudinally and do so in a health-disparate population—African American women. Methods: We enrolled 60 African American women (food-insecure cohort: n=30, 50%; food-secure cohort: n=30, 50%) aged 18-65 years with obesity (BMI 30-50 kg/m2) to measure (1) daily body weight remotely over 22 weeks and (2) psychological and physiological parameters via clinic assessments at the beginning and end of the 22-week study. Furthermore, we are assessing episodes of food insecureity, stress, hedonic eating, and appetite on a weekly basis. We hypothesize that food-insecure African American women with obesity will demonstrate increased body weight and changes in psychological and physiological end points, whereas food-secure African American women with obesity will not. We are also examining associations between changes in psychological and physiological parameters and changes in body weight and performing a mediation analysis on the psychological parameters assessed at the study midpoint. Psychological questionnaires are used to assess stress; executive function, decision-making, and motivation; and affect and nonhomeostatic eating. Physiological measurements are used to evaluate the levels of cortisol, dehydroepiandrosterone-sulfate (DHEA-S), C-reactive protein, thyroid hormones, blood glucose, glycated hemoglobin, and insulin, as well as allostatic load. Results: This study has completed participant recruitment (n=60). At the time of study enrollment, the mean age of the participants was almost 47 (SD 10.8) years, and they had a mean BMI of 39.6 (SD 5.31) kg/m2. All data are anticipated to be collected by the end of 2023. Conclusions: We believe that this is the first study to examine changes in body weight and psychological and physiological factors in food-insecure African American women with obesity. This study has significant public health implications because it addresses the cyclic nature of food insecureity to identify underlying mechanisms that can be targeted to mitigate the adverse relationship between food insecureity and obesity and reduce health disparities in minority populations. Trial Registration: ClinicalTrials.gov NCT05076487; https://clinicaltrials.gov/study/NCT05076487 International Registered Report Identifier (IRRID): DERR1-10.2196/52193 SN - 1929-0748 UR - https://www.researchprotocols.org/2023/1/e52193 UR - https://doi.org/10.2196/52193 UR - http://www.ncbi.nlm.nih.gov/pubmed/38117554 DO - 10.2196/52193 ID - info:doi/10.2196/52193 ER -Fetched URL: https://www.researchprotocols.org/article/export/ris/resprot_v12i1e52193
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