Abstract
Recent research on the epidemiology of substance use disorders (SUDs) has provided important insights into these conditions and their impact on public health. In the United States, annual surveys of drug use in household and school populations serve as one of the primary sources of information about the distribution of illicit drug use. This research has demonstrated continued shifts in trends in illicit drug use in the United States and called attention to rising rates of prescription drug misuse and abuse. Findings have also continued to highlight the substantial comorbidity of SUDs with other psychiatric disorders and with the ongoing HIV epidemic. Building on these foundations, future challenges for research in substance abuse epidemiology will include using novel methodologic approaches to further unravel the complex interrelationships that link individual vulnerabilities for SUDs, including genetic factors, with social and environmental risk factors.
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References and Recommended Reading
Fishbein D: The importance of neurobiological research to the prevention of psychopathology. Prev Sci 2000, 1:89–106.
Susser E, Bresnahan M: Origins of epidemiology. Ann N Y Acad Sci 2001, 954:6–18.
Johnston LD, O’Malley PM, Bachman JG, et al.: Monitoring the Future: National Survey Results on Drug Use, 1975–2008. Bethesda, MD: National Institute on Drug Abuse; 2009.
Substance Abuse and Mental Health Services Administration: Results From the 2007 National Survey on Drug Use and Health: National Findings. Rockville, MD: US Department of Health and Human Services; 2008.
Compton WM, Volkow ND: Major increases in opioid analgesic abuse: concerns and strategies. Drug Alcohol Depend 2006, 81:103–107.
Ballesteros MF, Budnitz DS, Sanford CP, et al.: Increase in deaths due to methadone in North Carolina. JAMA 2003, 290:40.
Hall AJ, Logan JE, Toblin RL, et al.: Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA 2008, 300:2613–2620.
Boyd CJ, McCabe SE, Cranford JA, et al.: Adolescents’ motivations to abuse prescription medications. Pediatrics 2006, 118:2472–2480.
McCabe SE, Boyd CJ, Young A: Medical and nonmedical use of prescription drugs among secondary school students. J Adolesc Health 2007, 40:76–83.
Compton WM, Grant BF, Colliver JD, et al.: Prevalence of marijuana use disorders in the United States: 1991–1992 and 2001–2002. JAMA 2004, 291:2114–2121.
Thomas YF, Compton WM: Rural populations are not protected from drug use and abuse. J Rural Health 2007, 23:1–3.
Gfroerer JC, Larson SL, Colliver JD: Drug use patterns and trends in rural communities. J Rural Health 2007, 23:10–15.
Community Epidemiology Work Group: Epidemiological Trends in Drug Abuse. Washington, DC: National Institute on Drug Abuse; 2004.
Compton WM, Thomas YF, Stinson FS, et al.: Prevalence, correlates, disability, and comorbidity of DSM-IV drug abuse and dependence in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 2007, 64:566–576.
Grant BF: Prevalence and correlates of drug use and DSM-IV drug dependence in the United States: results of the National Longitudinal Alcohol Epidemiologic Survey. J Subst Abuse 1996, 8:195–210.
Teesson M, Baillie A, Lynskey M, et al.: Substance use, dependence and treatment seeking in the United States and Australia: a cross-national comparison. Drug Alcohol Depend 2006, 81:149–155.
Beals J, Novins DK, Whitesell NR, et al.: Prevalence of mental disorders and utilization of mental health services in two American Indian reservation populations: mental health disparities in a national context. Am J Psychiatry 2005, 162:1723–1732.
Gilder DA, Wall TL, Ehlers CL: Comorbidity of select anxiety and affective disorders with alcohol dependence in southwest California Indians. Alcohol Clin Exp Res 2004, 28:1805–1813.
Gfroerer J, Penne M, Pemberton M, et al.: Substance abuse treatment need among older adults in 2020: the impact of the aging baby-boom cohort. Drug Alcohol Depend 2003, 69:127–135.
Colliver JD, Compton WM, Gfroerer JC, et al.: Projecting drug use among aging baby boomers in 2020. Ann Epidemiol 2006, 16:257–265.
Regier DA, Farmer ME, Rae DS, et al.: Comorbidity of mental disorders with alcohol and other drug abuse: results from the Epidemiologic Catchment Area (ECA) study. JAMA 1990, 264:2511–2518.
Warner LA, Kessler RC, Hughes M, et al.: Prevalence and correlates of drug use and dependence in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 1995, 52:219–229.
Grant BF: Comorbidity between DSM-IV drug use disorders and major depression: results of a national survey of adults. J Subst Abuse 1995, 7:481–497.
Grant BF, Stinson FS, Dawson DA, et al.: Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 2004, 61:807–816.
Merikangas KR, Mehta RL, Molnar BE, et al.: Comorbidity of substance use disorders with mood and anxiety disorders: results of the International Consortium in Psychiatric Epidemiology. Addict Behav 1998, 23:893–907.
Swendsen JD, Merikangas KR: The comorbidity of depression and substance use disorders. Clin Psychol Rev 2000, 20:173–189.
Conway KP, Compton W, Stinson FS, et al.: Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2006, 67:247–257.
Compton WM, Conway KP, Stinson FS, et al.: Prevalence, correlates, and comorbidity of DSM-IV antisocial personality syndromes and alcohol and specific drug use disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2005, 66:677–685.
Kendler KS, Prescott CA, Myers J, et al.: The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 2003, 60:929–937.
Centers for Disease Control and Prevention: Cases of HIV infection and AIDS in the United States and dependent areas, 2007. Available at http://cdc.gov/hiv/topics/surveillance/resources/reports/2007report/default.htm. Accessed March 27, 2009.
Woody GE, Donnell D, Seage GR, et al.: Non-injection substance use correlates with risky sex among men having sex with men: data from HIVNET. Drug Alcohol Depend 1999, 53:197–205.
Mansergh G, Purcell DW, Stall R, et al.: CDC consultation on methamphetamine use and sexual risk behavior for HIV/STD infection: summary and suggestions. Public Health Rep 2006, 121:127–132.
Krawczyk CS, Molitor F, Ruiz J, et al.: Methamphetamine use and HIV risk behaviors among heterosexual men—preliminary results from five northern California counties, December 2001–November 2003. MMWR Morb Mortal Wkly Rep 2006, 55:273–277.
Walkup J, Blank MB, Gonzalez JS, et al.: The impact of mental health and substance abuse factors on HIV prevention and treatment. J Acquir Immune Defic Syndr 2008, 47(Suppl 1):S15–S19.
Des Jarlais DC, Semaan S: HIV prevention for injecting drug users: the first 25 years and counting. Psychosom Med 2008, 70:606–611.
Mustanski B, Garofalo R, Herrick A, et al.: Psychosocial health problems increase risk for HIV among urban young men who have sex with men: preliminary evidence of a syndemic in need of attention. Ann Behav Med 2007, 34:37–45.
Friedman SR, Tempalski B, Cooper H, et al.: Metropolitan area characteristics, injection drug use and HIV among injectors. In Geography and Drug Addiction. Edited by Thomas YF, Richardson D, Cheung I. Washington, DC: Springer; 2008:255–265.
Bierut LJ, Dinwiddie SH, Begleiter H, et al.: Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. Arch Gen Psychiatry 1998, 55:982–988.
Chassin L, Pitts SC, Prost J: Binge drinking trajectories from adolescence to emerging adulthood in a high-risk sample: predictors and substance abuse outcomes. J Consult Clin Psychol 2002, 70:67–78.
Moss HB, Lynch KG, Hardie TL, et al.: Family functioning and peer affiliation in children of fathers with antisocial personality disorder and substance dependence: associations with problem behaviors. Am J Psychiatry 2002, 159:607–614.
Compton WM, Cottler LB, Ridenour T, et al.: The specificity of family history of alcohol and drug abuse in cocaine abusers. Am J Addict 2002, 11:85–94.
Caspi A, McClay J, Moffitt TE, et al.: Role of genotype in the cycle of violence in maltreated children. Science 2002, 297:851–854.
Foley DL, Eaves LJ, Wormley B, et al.: Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Arch Gen Psychiatry 2004, 61:738–744.
Galea S, Nandi A, Vlahov D: The social epidemiology of substance use. Epidemiol Rev 2004, 26:36–52.
Burton LM, Jarrett RL: In the mix, yet on the margins: the place of families in urban neighborhood and child development research. J Marriage Fam 2000, 62:444–465.
Sampson RJ, Morenoff JD, Gannon-Rowley T: Assessing “neighborhood effects:” social processes and new directions in research. Ann Rev Sociol 2002, 28:443–478.
Galea S, Hall C, Kaplan GA: Social epidemiology and complex system dynamic modelling as applied to health behavior and drug use research. Int J Drug Policy 2009, 20:209–216.
Young EA, Breslau N: Cortisol and catecholamines in posttraumatic stress disorder: an epidemiologic community study. Arch Gen Psychiatry 2004, 61:394–401.
Cozier YC, Palmer JR, Rosenberg L: Comparison of methods for collection of DNA samples by mail in the Black Women’s Health Study. Ann Epidemiol 2004, 14:117–122.
Shiffman S, Stone AA, Hufford MR: Ecological momentary assessment. Annu Rev Clin Psychol 2008, 4:1–32.
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Schulden, J.D., Thomas, Y.F. & Compton, W.M. Substance abuse in the United States: Findings from recent epidemiologic studies. Curr Psychiatry Rep 11, 353–359 (2009). https://doi.org/10.1007/s11920-009-0053-6
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DOI: https://doi.org/10.1007/s11920-009-0053-6