Tumor tissue and ascites from patients with ovarian cancer contain high levels of cells with all the hallmarks of regulatory T cells. These cells migrate into the tumor microenvironment in a process mediated by the chemokine CCL22, and are capable of suppressing antitumor responses (pages 942–949).
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Shevach, E. Fatal attraction: tumors beckon regulatory T cells. Nat Med 10, 900–901 (2004). https://doi.org/10.1038/nm0904-900
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DOI: https://doi.org/10.1038/nm0904-900
