To provide antibodies for specifically detecting pathogenic prions for human origin, to provide methods for detecting pathogenic prions, and, in particular, to provide a conformation-dependent immunoassay method for detecting pathogenic prion proteins in a sample of a body fluid, containing a PrP protein.例文帳に追加

ヒト起源の病原性プリオンの特異的検出抗体及び病原性プリオンの検出方法、特に、ＰｒＰタンパク質を含む体液試料で病原性プリオンタンパク質を検出するコンフォメーション依存イムノアッセイの方法の提供。 - 特許庁

This invention also provides the evaluation system for direct interaction among proteins such as binding of ligand such as a denatured LDL to an SR-A or screening of an agonist or antagonist of the SR-A by using the prepared protein having the polymeric conformation.例文帳に追加

またこの多量体のコンフォメーションを持つ標品蛋白質を用いる、変性ＬＤＬなどのリガンドとＳＲ−Ａとの結合、あるいはＳＲ−Ａのアゴニストやアンタゴニストのスクリーニングなど、直接的な蛋白質間相互作用の評価系。 - 特許庁

Provided is a microalgae poly-β-1→4-N-acetylglucosamine which contains no protein, substantially contains no other organic and inorganic contaminants, comprises approximately 4,000 to approximately 150,000 N-acetylglucosamine monosaccharide that is covalently bound in a β-1→4 conformation, and has a molecular weight ranging from approximately 800,000 daltons to approximately 30,000,000 daltons.例文帳に追加

タンパク質を含まず、他の有機汚染物質を実質的に含まず、無機汚染物質を実質的に含まない、β-1→4配置で共有結合された約4,000〜約150,000のN-アセチルグルコサミン単糖を含んでなり、約800,000ダルトン〜約3,000万ダルトンの分子量を有する微小藻類ポリ-β-1→4-N-アセチルグルコサミン。 - 特許庁

To provide a virtual screening method and device capable of highly accurately predicting a bonding conformation and bonding capacity between protein and a compound more than conventional accuracy, by constructing an optimal prediction model on scoring, by learning with a teacher by using an energy term on a non-bonding structure.例文帳に追加

非結合構造に関するエネルギー項を用いて教師付き学習を行うことで、スコアリングに関する最適な予測モデルを構築し、従来よりも高い精度で蛋白質・化合物間の結合配座や結合能を予測できる仮想スクリーニング方法及び装置を提供する。 - 特許庁

The microalgae poly-β-1→4-N-acetylglucosamine having a molecular weight of about 800,000 daltons to about 30 million daltons comprises about 4,000 to about 150,000 N-acetylglucosamine monosaccharides covalently bonded in a β-1→4 conformation, free of protein, substantially free of other organic contaminants and substantially free of inorganic contaminants.例文帳に追加

タンパク質を含まず、他の有機汚染物質を実質的に含まず、無機汚染物質を実質的に含まない、β-1→4配置で共有結合された約4,000〜約150,000のN-アセチルグルコサミン単糖を含んでなり、約800,000ダルトン〜約3,000万ダルトンの分子量を有する微小藻類ポリ-β-1→4-N-アセチルグルコサミン。 - 特許庁