Polysorbate: Difference between revisions
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{{Short description|Class of chemical compounds}} |
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{{Missing information|cross-reaction with PEG hypersensitivity [PMID |
{{Missing information|cross-reaction with PEG hypersensitivity [PMID 30557713]|date=April 2021}} |
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[[File:Polysorbate 60.png|thumb|right|300px|Polysorbate |
[[File:Polysorbate 60.png|thumb|right|300px|Polysorbate 20, a compound used as a food additive in some pudding mixes to prevent scorching during preparation]] |
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'''Polysorbates''' are a class of [[emulsifier]]s used in some pharmaceuticals and food preparation. They are commonly used in oral and topical pharmaceutical dosage forms. They are also often used in cosmetics to solubilize [[essential oil]]s into water-based products. Polysorbates are oily liquids derived from [[ethoxylation|ethoxylated]] [[sorbitan]] (a derivative of [[sorbitol]]) [[ester]]ified with [[fatty acid]]s. Common brand names for polysorbates include Kolliphor,<ref>{{Cite web |title=Pharmaceutical Polysorbates |url=https://pharma.basf.com/chemistry/polysorbates-and-sorbitan-esters?at_medium=display&at_campaign=enp_baw_glob_en_sol_tra_wikipedia&at_creation=landing-page_wikipedia_chemistry-page_basf-wikipedia-article&at_channel=wikipedia&at_format=chemistry-page&at_variant=basf-wikipedia-article |access-date=2021-04-27 |website=pharmaceutical.basf.com |language=en}}</ref> Scattics, Alkest, Canarcel, |
'''Polysorbates''' are a class of [[emulsifier]]s used in some pharmaceuticals and food preparation. They are commonly used in oral and topical pharmaceutical dosage forms. They are also often used in cosmetics to solubilize [[essential oil]]s into water-based products. Polysorbates are oily liquids derived from [[ethoxylation|ethoxylated]] [[sorbitan]] (a derivative of [[sorbitol]]) [[ester]]ified with [[fatty acid]]s. Common brand names for polysorbates include Kolliphor,<ref>{{Cite web |title=Pharmaceutical Polysorbates |url=https://pharma.basf.com/chemistry/polysorbates-and-sorbitan-esters?at_medium=display&at_campaign=enp_baw_glob_en_sol_tra_wikipedia&at_creation=landing-page_wikipedia_chemistry-page_basf-wikipedia-article&at_channel=wikipedia&at_format=chemistry-page&at_variant=basf-wikipedia-article |access-date=2021-04-27 |website=pharmaceutical.basf.com |language=en}}</ref> Scattics, Alkest, Canarcel, Tween,<ref name=Ullmann>Hubert Schiweck, Albert Bär, Roland Vogel, Eugen Schwarz, Markwart Kunz, Cécile Dusautois, Alexandre Clement, Caterine Lefranc, Bernd Lüssem, Matthias Moser, Siegfried Peters "Sugar Alcohols" Ullmann's Encyclopedia of Industrial Chemistry, 2012, Wiley-VCH, Weinheim. {{doi|10.1002/14356007.a25_413.pub3}}</ref> and Kotilen. |
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== Examples == |
== Examples == |
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== External links == |
== External links == |
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* {{CPID|id=1547|name=PEG-60 (Polysorbate 60)}} |
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[[Category:Non-ionic surfactants]] |
[[Category:Non-ionic surfactants]] |
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[[Category:Colloidal chemistry]] |
[[Category:Colloidal chemistry]] |
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[[Category:E-number additives]] |
[[Category:E-number additives]] |
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Latest revision as of 23:03, 18 March 2024
 | This article is missing information about cross-reaction with PEG hypersensitivity [PMID 30557713]. (April 2021) |
Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are commonly used in oral and topical pharmaceutical dosage forms. They are also often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Common brand names for polysorbates include Kolliphor,[1] Scattics, Alkest, Canarcel, Tween,[2] and Kotilen.
Examples
[edit]- Polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate)
- Polysorbate 40 (polyoxyethylene (20) sorbitan monopalmitate)
- Polysorbate 60 (polyoxyethylene (20) sorbitan monostearate)
- Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate)
The number following the 'polysorbate' part is related to the type of major fatty acid associated with the molecule. Monolaurate is indicated by 20, monopalmitate is indicated by 40, monostearate by 60, and monooleate by 80. The number 20 following the 'polyoxyethylene' part refers to the total number of oxyethylene (–CH2CH2O–) groups found in the molecule.
See also
[edit]References
[edit]- ^ "Pharmaceutical Polysorbates". pharmaceutical.basf.com. Retrieved 2021-04-27.
- ^ Hubert Schiweck, Albert Bär, Roland Vogel, Eugen Schwarz, Markwart Kunz, Cécile Dusautois, Alexandre Clement, Caterine Lefranc, Bernd Lüssem, Matthias Moser, Siegfried Peters "Sugar Alcohols" Ullmann's Encyclopedia of Industrial Chemistry, 2012, Wiley-VCH, Weinheim. doi:10.1002/14356007.a25_413.pub3
External links
[edit]
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