diff --git a/packages/runtime-core/src/apiCreateApp.ts b/packages/runtime-core/src/apiCreateApp.ts
index b0c8a3f2bba..edc63ac9ae4 100644
--- a/packages/runtime-core/src/apiCreateApp.ts
+++ b/packages/runtime-core/src/apiCreateApp.ts
@@ -236,6 +236,12 @@ export function createAppAPI<HostElement>(
       mixin(mixin: ComponentOptions) {
         if (__FEATURE_OPTIONS_API__) {
           if (!context.mixins.includes(mixin)) {
+            for (let m in mixin) {
+              if (isFunction(mixin[m])) {
+                // mark globalMixin
+                mixin[m]._isGlobalMixin = true
+              }
+            }
             context.mixins.push(mixin)
           } else if (__DEV__) {
             warn(
diff --git a/packages/runtime-core/src/apiLifecycle.ts b/packages/runtime-core/src/apiLifecycle.ts
index ec39308eea5..e7b96175ec2 100644
--- a/packages/runtime-core/src/apiLifecycle.ts
+++ b/packages/runtime-core/src/apiLifecycle.ts
@@ -14,18 +14,23 @@ import { DebuggerEvent, pauseTracking, resetTracking } from '@vue/reactivity'
 
 export { onActivated, onDeactivated } from './components/KeepAlive'
 
+export type WRAPPEDHOOK = {
+  (hook: Function & { __weh?: WRAPPEDHOOK; _isGlobalMixin?: boolean }): void
+  _isGlobalMixin?: boolean
+}
+
 export function injectHook(
   type: LifecycleHooks,
-  hook: Function & { __weh?: Function },
+  hook: Function & { __weh?: WRAPPEDHOOK; _isGlobalMixin?: boolean },
   target: ComponentInternalInstance | null = currentInstance,
   prepend: boolean = false
-): Function | undefined {
+): WRAPPEDHOOK | undefined {
   if (target) {
     const hooks = target[type] || (target[type] = [])
     // cache the error handling wrapper for injected hooks so the same hook
     // can be properly deduped by the scheduler. "__weh" stands for "with error
     // handling".
-    const wrappedHook =
+    const wrappedHook: WRAPPEDHOOK =
       hook.__weh ||
       (hook.__weh = (...args: unknown[]) => {
         if (target.isUnmounted) {
@@ -43,8 +48,22 @@ export function injectHook(
         resetTracking()
         return res
       })
+    if (hook._isGlobalMixin) {
+      wrappedHook._isGlobalMixin = hook._isGlobalMixin
+    }
     if (prepend) {
-      hooks.unshift(wrappedHook)
+      let index = -1
+      for (let i = hooks.length - 1; i >= 0; i--) {
+        if ((hooks[i] as WRAPPEDHOOK)._isGlobalMixin) {
+          index = i
+          break
+        }
+      }
+      if (index === -1) {
+        hooks.unshift(wrappedHook)
+      } else {
+        hooks.splice(index + 1, 0, wrappedHook)
+      }
     } else {
       hooks.push(wrappedHook)
     }
@@ -63,12 +82,17 @@ export function injectHook(
   }
 }
 
+export interface HOOK {
+  (e: DebuggerEvent): void
+  _isGlobalMixin?: boolean
+}
+
 export const createHook =
-  <T extends Function = () => any>(lifecycle: LifecycleHooks) =>
+  <T extends HOOK>(lifecycle: LifecycleHooks) =>
   (hook: T, target: ComponentInternalInstance | null = currentInstance) =>
     // post-create lifecycle registrations are noops during SSR (except for serverPrefetch)
     (!isInSSRComponentSetup || lifecycle === LifecycleHooks.SERVER_PREFETCH) &&
-    injectHook(lifecycle, hook, target)
+    injectHook(lifecycle, hook, target, hook._isGlobalMixin ? true : false)
 
 export const onBeforeMount = createHook(LifecycleHooks.BEFORE_MOUNT)
 export const onMounted = createHook(LifecycleHooks.MOUNTED)
@@ -86,11 +110,12 @@ export const onRenderTracked = createHook<DebuggerHook>(
   LifecycleHooks.RENDER_TRACKED
 )
 
-export type ErrorCapturedHook<TError = unknown> = (
-  err: TError,
-  instance: ComponentPublicInstance | null,
-  info: string
-) => boolean | void
+export type ErrorCapturedHook<TError = unknown> = {
+  (err: TError, instance: ComponentPublicInstance | null, info: string):
+    | boolean
+    | void
+  _isGlobalMixin?: boolean
+}
 
 export function onErrorCaptured<TError = Error>(
   hook: ErrorCapturedHook<TError>,
diff --git a/packages/runtime-core/src/componentOptions.ts b/packages/runtime-core/src/componentOptions.ts
index c482d051965..24c481355ee 100644
--- a/packages/runtime-core/src/componentOptions.ts
+++ b/packages/runtime-core/src/componentOptions.ts
@@ -42,7 +42,8 @@ import {
   onRenderTriggered,
   DebuggerHook,
   ErrorCapturedHook,
-  onServerPrefetch
+  onServerPrefetch,
+  HOOK
 } from './apiLifecycle'
 import {
   reactive,
@@ -756,12 +757,22 @@ export function applyOptions(instance: ComponentInternalInstance) {
 
   function registerLifecycleHook(
     register: Function,
-    hook?: Function | Function[]
+    hook?: HOOK | HOOK[] | ErrorCapturedHook | ErrorCapturedHook[]
   ) {
     if (isArray(hook)) {
-      hook.forEach(_hook => register(_hook.bind(publicThis)))
+      hook.forEach(_hook => {
+        const bind = _hook.bind(publicThis)
+        if (_hook._isGlobalMixin) {
+          bind._isGlobalMixin = true
+        }
+        register(bind)
+      })
     } else if (hook) {
-      register((hook as Function).bind(publicThis))
+      const bind = hook.bind(publicThis)
+      if (hook._isGlobalMixin) {
+        bind._isGlobalMixin = true
+      }
+      register(bind)
     }
   }
 
diff --git a/packages/runtime-core/src/components/KeepAlive.ts b/packages/runtime-core/src/components/KeepAlive.ts
index 4b2c7288581..be568c9f5d0 100644
--- a/packages/runtime-core/src/components/KeepAlive.ts
+++ b/packages/runtime-core/src/components/KeepAlive.ts
@@ -21,7 +21,8 @@ import {
   injectHook,
   onUnmounted,
   onMounted,
-  onUpdated
+  onUpdated,
+  WRAPPEDHOOK
 } from '../apiLifecycle'
 import {
   isString,
@@ -407,7 +408,7 @@ function registerKeepAliveHook(
 }
 
 function injectToKeepAliveRoot(
-  hook: Function & { __weh?: Function },
+  hook: Function & { __weh?: WRAPPEDHOOK; _isGlobalMixin?: boolean },
   type: LifecycleHooks,
   target: ComponentInternalInstance,
   keepAliveRoot: ComponentInternalInstance

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