To remain mentally fit for as long as possible in old age, it is important to understand which risk factors could impact cognitive functioning already early in life. Scientists led by the German Centre for Neurodegenerative ...
Jan 23, 2025
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Late-onset Alzheimer's disease is a debilitating, progressive neurodegenerative disease that affects about 7 million Americans, a figure that is expected to nearly double by 2050, according to the Alzheimer's Association. ...
Jan 22, 2025
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A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and ...
Jan 22, 2025
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Inflammation is triggered by the immune system and is part of the body's natural response to injuries or disease. However, abnormal inflammation has recently been established as a hallmark for pathologies that were previously ...
Jan 21, 2025
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A University of the Basque Country (UPV/EHU) study proves that the WIN55.212-2 drug protects the brain and reverses the initial cognitive damage caused by dementia.
Jan 14, 2025
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Concussions and repetitive head trauma in sports like football and boxing, once accepted as an unpleasant consequence of intense athletic competition, are now recognized as serious health threats.
Jan 7, 2025
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Scientists have uncovered a powerful ally in the fight against neurodegenerative diseases: a nucleolar complex that plays a pivotal role in maintaining cellular health through protein homeostasis (proteostasis), by which ...
Jan 3, 2025
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Alzheimer's disease (AD) is a debilitating neurodegenerative disorder associated with a progressive decline in memory and mental abilities, which can significantly hinder people's ability to complete daily tasks. Past studies ...
Diseases marked by progressive deterioration of the brain—neurodegeneration—have proven challenging to understand and treat. These common conditions affect millions of patients and families around the world, yet efforts ...
Dec 19, 2024
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Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ...
Dec 19, 2024
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Neurodegenerative disease (Greek νέυρο-, néuro-, "nerval" and Latin dēgenerāre, "to decline" or "to worsen") is a condition in which cells of the brain and spinal cord are lost. The brain and spinal cord are composed of neurons that do different functions such as controlling movements, processing sensory information, and making decisions. Cells of the brain and spinal cord are not readily regenerated en masse, so excessive damage can be devastating. Neurodegenerative diseases result from deterioration of neurons or their myelin sheath which over time will lead to dysfunction and disabilities resulting from this.
Some sources limit the term "degenerative" to conditions primarily affecting gray matter that are not associated with a obvious inciting event.
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