Fig. 5.
Quantification of neuronal death after KA injection. Sections treated as in Figure 4 were grouped by time points. The amount of neurodegeneration was measured using Scion Image and presented as the percentage of total hippocampal length of the ipsilateral injected side (SEM). These data are graphically presented as well. Note that the NF-L-tPA mice show a slower increase of neuronal loss at early time points (up to 2 d) compared with wild-type or Fms-tPA mice, although they match the percentage lost by Fms-tPA mice by 5 d.