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Heterocycles are widely utilized organic molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis or functionalization still remains challenging with difficulty to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop green synthetic methods for the preparation of these molecules. This series aims to do so, by collecting developments into common themes.
Dr. Bubun Banerjee received his Ph.D. degree from Visva-Bharati University, Santiniketan, West Bengal, India. He has nearly nine years of experience in the field of research related to green and sustainable developments. Presently he is working as an assistant professor of chemistry at the Department of Chemistry, Akal University, Talwandi Sabo, Bathinda, Punjab, India. Dr. Banerjee published more than 90 research articles in the internationally renowned journals and authored ten book chapters; he also co-edited eight books and guest edited nine different special thematic issues of different journals.
Multicomponent synthesis may provide new and green routes for obtaining bioactive heterocycles. These methods produce less organic waste due to no longer removing solvent and other components between reaction steps. It can be applied to the synthesis of heterocycles with reactions such as the Biginelli reaction. This book explores the use of multi-component reactions for various heterocyclic structures with bioactivity.
The solvent-free approach provides green and alternative synthetic methods for obtaining diverse bioactive heterocycles. The solvent is frequently the primary component of synthetic protocol and contributes to significant waste. Additionally, its removal processes are energy intensive and substantial. This book explores different solvent-free procedures for efficiently synthesising heterocyclic analogues of immense biological importance and other applications.
Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds.
THE SERIES: GREEN BIOACTIVE HETEROCYCLES Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.
Bioactive Five-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active five-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of five-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive five-membered heterocycles.
Bioactive Three-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active three-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of three-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive three-membered heterocycles.
Bioactive Four-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active four-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of four-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive four-membered heterocycles.
Carbohydrates in Chemistry and Biology provides detailed information about the green synthesis, biological importance and catalytic applications of carbohydrate derivatives. It covers various topics including carbohydrate decorated compounds, bioconjugation, carbohydrate functionalized heterocycles, carbohydrate-spiro-heterocycles, heterocycles from carbohydrate precursors and natural sources of bioactive carbohydrates.