His mother was the French Lady Comynyplatt Henrietta de Gacher, his father was the British Lieutenant William Graham Niven, who died in the war when David was six years old. Niven was considered a difficult child to educate and had to change schools often until he finally went to Sandhurst Military Academy. He came to Malta as a soldier, left the army here and went to Canada, where he worked as a lumberjack, bridge builder, journalist and whiskey salesman. After detours via New York and Cuba, Niven settled in California in 1934, where he had his first roles as an extra. He appeared in smaller films until the Second World War and then had to go to war for the British army.

In between, he also starred in propaganda films. Niven fought on the British front at Dunkirk and was promoted to colonel in 1944. General Eisenhower decorated him with the medals of the American Legion of Merit. From his first marriage to Primula Rollo, whom he married in 1940, Niven had two sons, David and Jamie. After his wife died in an accident in 1946, he married the Swede Hjordis Tersmeden in 1948, and his daughters Kristine and Fiona came from this marriage. In 1952, Niven founded the television production "Four Star TV" with Charles Boyer and other colleagues and starred in the self-produced series "The David Niven Show" and "Rogues Against Crooks". He had already been successful as an actor for a long time.

Niven starred in the 1946 English production of Error in the Afterlife and then returned to Hollywood. He celebrated successes with "The Virgin on the Roof", "Bonjour Tristesse", "The Guns of Navarone", "55 Days in Peking", "The Pink Panther", "Lady L." and with "Casino Royale". In 1959 he reached the peak of his success when he was honored with the Oscar for Best Actor for Separated from Table and Bed. His most beautiful film role was that of "Phileas Fogg" in the Jules Verne film adaptation "Around the World in 80 Days". Niven later demonstrated his enormous skills in many other films. In the 1970s and 1980s he starred in "Vampira", "A Corpse for Dessert", "Death on the Nile", "The Lion Shows its Claws" and in "Grandpa Seldom Comes Alone".

In 1982 and 1983 he had his last two roles in "The Pink Panther is Hunted" and "The Curse of the Pink Panther". Niven retired and lived on the Cote d'Azur and in Switzerland.

David Niven died on July 29, 1983 in Switzerland as a result of the nervous disease ALS. He made part of his inheritance available to medical research.