Isabel Sanford was a Broadway actress for over thirty years before moving to Hollywood. She made numerous guest appearances on TV, including a stint as a supporting cast member on The Carol Burnett Show (1967). Until her passing, Isabel continued to act frequently, most recently in a series of commercials for Old Navy stores with The Jeffersons (1975) co-star, Sherman Hemsley. She made several commercials for Nick-at-Nite as well when the cable channel premiered The Jeffersons (1975).