- Members have included O'Kelly Isley, Rudolph Isley, Ronald Isley, Ernie Isley, Marvin Isley, Chris Jasper, Everett Collins
- Jimi Hendrix played on two of the group's singles (under the name "Jimmy James"), and during 1964 was a member of the group's touring band.
- Their song "Summer Breeze" was covered by Seals & Crofts in 1977. Several bars from the melody of it were used as background rhythm by rap artists Snoop Dogg and Dr. Dre for 1991's "G Thang".
- Not only has their hit "Shout" been sung by The Temptations, its bars have been re-mixed for the opening of House of Pain's 1992 successful rap single "Jump Around".
- Founders of T-Neck Records.
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