- When she was seven she told her parents when she grew up she wanted to write stories about murder and to live in America.
- Was eight months pregnant with her son when she completed filming Promising Young Woman (2020) and was pregnant with her second child while accepting an Academy Award for Best Original Screenplay for the movie.
- She is the seventh woman and first British woman to be nominated for Best Director at the Academy Awards.
- Graduated from Oxford.
- Directed 1 actor to an Oscar nomination: Carey Mulligan, who was nominated for Promising Young Woman (2020).
- Returned to work three months after giving birth to her son to begin filming season 4 of The Crown (2016).
- Daughter of Alister Theodore "Theo" (b. 1951), born in Egypt, and Emma Shirley Louise (née MacGregor) Fennell (b. 1957), born in Hampshire.
- Older sister of Coco Poppy Fennell (b. June 1988), a fashion designer.
- Mother, with husband Chris Vernon, of a son (b. May 2019) and second child whose gender and name unknown (b. 2021).
- Maternal granddaughter of Alasdair (1930-2010) and Jenifer (née Tod) MacGregor (1932-2017), and paternal granddaughter of Beryl Ruth (Verity) and Major Alister Ivor Fennell.
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