The college in the series, Randolph-Harrington College, is fictitious and is directly based on Emerson College in Boston. Star Anthony Clark and co-creator Max Mutchnick are alumni of Emerson, and were members of the graduating classes of 1986 and 1987 respectively.
Patrick Fabian played Professor Jack Reed in the pilot episode, but was replaced by Vincent Ventresca for the remainder of the series.
Anthony Clark, Hedy Burress, Traylor Howard, Tasha Smith, and Steve Paymer are the only actors to appear in all 32 episodes of the series.
In one episode, Anthony Clark's character Boyd Pritchett jokes that he saw Steve Paymer's character Leonard Prince in the movie City Slickers (1991). In reality, Steve Paymer's younger brother David Paymer co-starred in the film as ice cream magnate Ira Shalowitz.
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