As all the other comments have been made about only Series 1 and 2 and Holby is now near the end of its 4th series, I need to renew them. Of course I have grown up since the last comment I made ('mathewowen') and now realise that Holby City really isn't that realistic when you look at the hard graft and rush that goes on in real hospitals. It's true that a lot of the staff are more like counsellors than medical staff, and it's also true that a lot of the one episode characters (in every episode different patients are featured with their own storylines) come from soaps.
However, Holby City is still watchable stuff, and I think with the two new wards: Maternity and the Children's Ward, every episode is even more different, and there are so many new characters that are, for the most part, well played.
Holby is now viewed as a soap because of its all year round showing, and what with more staff storylines involving affairs and staff becoming patients, it's still good drama. Watch out for some eps where there are some scenes set in Casualty (Holby is a spin off of Casualty) with Casualty characters (likewise in a recent episode Mr Meyer was featured in Casualty being as arrogant as ever).
Okay, some could say that there are more staff storylines as the writers as exhausting the patient storylines. However, there are have been some pretty memorable staff storylines in the past 2 series, such as Mr Meyer being shot, Janice Taylor's (she's the consultant on the children's ward) husband having an affair with Sister Williams, Kath Shaugnessy playing victim to domestic violence, Liam Evans learning to cope with life in a wheelchair, Victoria Merrick being murdered (it was a classic 'whodunnit') and Danny Shaugnessy marrying an illegal immigrant who's first husband turned up though she thought he was dead, to name a few.
And the good thing about Holby City is that the whole set and atmosphere is like a real British hospital. You can almost smell the disinfectant!
Watch Holby City next time it's on and see for yourself. It's good drama.