The scene where Shah Rukh Khan walks into a lounge (as himself in the film) and meets Farhan Akhtar for the first time, he is shown to be accompanied by a man of his age. This guy is none other than Mushtaq Sheikh who is Shahrukh Khan's age old friend in real life and has written quite a few books on him apart from penning Om Shanti Om (2007) and also acting in it. In a way he is related to the plot. When Shah Rukh Khan tells Farhan Akhtar that he should not be forgetting his friends from the old times, a message is being conveyed because the superstar himself is shown to be in company of those (read Mushtaq) who have been with him through his good and bad times.
In one of the first scenes of the film, Aamir Khan is shown to be giving a shot for an imaginary Rajkumar Hirani film. This is a nod to the fact that the next venture of both Aamir and Rajkumar Hirani after Luck by Chance is together for the movie 3 Idiots (2009)
Abhishek Bachchan is someone who avoids controversies, more so if he has to accept a movie that has been rejected by someone else. This is what he does to the character of Rommy Rolly (Rishi Kapoor) in his cameo in the film and politely refuses to be a part of his film. And when he says 'Daddy says Hi!' it brings the real life touch to the proceedings because this means 'End of conversation'
Ranbir Kapoor in his cameo as himself is a rising star whose stocks are on a high, he is shown to be this sweet talking youngster who is embarrassed enough to be saying no to an old time director and even hails him as his father figure. However, in the moment of reckoning when he has to take a call on signing a film, he comes up with an age old excuse - 'No Dates'. He doesn't say no, he just says - "Let's start working on the film in 2015"
The writer/director Anurag Kashyap is playing a frustrated writer, in Luck By Chance. Someone who is ridiculed as an 'Institute' when he tries to write something that defies the Bollywood clichés. The producer also mocks him by saying that he doesn't want to make the movie for a film festival, which is a dig at Mr. Anurag Kashyap whose movies, which mostly get banned in India or struggle to get a good producer, work quite well at various prestigious film festivals (e.g. Black Friday (2004), Paanch (2003)). Anurag is shown as a writer who is forced to do DVD rip offs and not complain when changes are asked to be made, something that cleverly reflects on his career as writer so far.
Shah Rukh Khan, Aamir Khan: This film has a unique distinction of bringing together the actors in the same film, although their roles were very small, and they don't even share any scene together on screen but this has never happened before this movie and is very unlikely to happen too, given the busy schedules and the huge stardom of both the actors.