Join Dennis and Billy Ray Cyrus as they get into some personal stories about Billy Ray's life as a baseball player, then as a left-handed guitarist, who went on to be one of the most successful musicians of modern country music history. Where did "Achy Breaky Heart" come from? How did he meet his wife? What happened to his dog in college? Billy Ray goes into his deep religious and philosophical ideals with Dennis.

John Carter Cash is the child of Johnny Cash and June Carter. Dennis and John talk about growing up with wildly successful parents, performing on stage with his dad as a child, drug and alcohol addiction, his life at "The Cabin", his lineage and love of farming, and life in Nashville during a global pandemic. They also talk about John's career as a musician, and as a film director.

On this episode of The Dennissance, Dennis is joined by long-time friend and confidant, Billy Bush. Four years ago, when the infamous tapes were revealed, Dennis sent his buddy a kind and uplifting message that aided in Billy's eventual recovery. Now, they're talking about the impact of that event, his process of recovery, and the hope he holds in his future, along with what it's like to play golf with former presidents.

On this episode of The Dennissance with Dennis Quaid, Dennis gets to the heart of the American Dream with baseball soon-to-be hall-of-famer, Albert Pujols. Albert talks at length about his history of baseball, from growing up in the Dominican Republic, to moving to the United States, to meeting his wife, starting a family, struggling to support his family, and his eventual career as one of the highest paid baseball players of all times, playing for the Los Angeles Angeles. But that's not all; Albert's and Dennis talk about the relationship Albert has with his daughter, and how it led him to create the Pujols Family Foundation; a foundation dedicated to helping those living with Down Syndrome, and to improve the lives of the impoverished in the Dominican Republic.

On this episode, Dennis talks to former TV love-interest, and current Real Housewives of Beverly Hills star, Garcelle Beauvais. Garcelle and Dennis go back to the beginning of her career, from her life before America in Haiti, her modeling career, her TV acting career, and finally, her life as a reality TV star. She's also a doting mother, who has proudly brought her children into her life as a TV star, but only by the promise of their own payment. Join Dennis in this episode of TV drama and untold stories about Garcelle and Jamie Foxx.

On this episode of The Dennissance, Dennis Quaid is joined by comedic Los Angeleno and podcast legend, Adam Carolla. Growing up in "the valley" Adam never expected to have a successful career in entertainment. He was on a course to work hourly construction job until he aged out. This conversation tells all the stories about growing up without many resources, having a deep desire for something more in his life, his struggles, failures, and his efforts to achieve his goals.

On this episode of The Dennissance with Dennis Quaid, Dennis sits with country music legend Clint Black. Together they talk through how Clint dedicated his life to music, instead of pursuing his dreams of being an astronaut. They also talk at length about how Clint met and fell in love with his wife, Lisa Hartman Black. They also discuss how Covid-19 is affecting his tour schedules, and how his faith is shaped by more than one perspective.

On this incredible episode of The Dennissance, Dennis Quaid speaks with Jimmy Morris, the real live "Rookie". When Dennis was cast as the character of Jimmy Morris in the movie The Rookie, he never could have dreamt that their real life friendship would be so long-standing. Here they are, 20 years later, with a lifetime of stories built together about baseball, dreams, challenges, and accomplishments. Together they share details of the story that turned Jimmy into a legend on the field, and eventually took him to the stage as a motivational speaker on the miracle of his sudden healing.

On this season finale episode of The Dennissance with Dennis Quaid, Dennis talks to long-time friend and fellow legendary actor, Gary Busey. From drug addiction and recovery to 80's parties, to their first Hollywood roles, and how they blazed the trails of being discovered, Gary and Dennis talk through their lives in parallel. They also take a break from talking with guitars in hand, and voices on their mics, for a truly one-of-a-kind audio experience. Learn about Gary's past life regression sessions, Viking cat funerals and much, much more, on this special episode of The Dennissance.

Season 2 of The Dennissance kicks off with a very special episode. Legendary news personality Katie Couric joins Dennis to discuss her love of The Parent Trap. This episode also includes a Parent Trap Reunion Katie moderated with Dennis, Lindsay Lohan, writer-director Nancy Meyers, Lisa Ann Walter, Simon Kunz and others.

On this episode of The Dennissance, Dennis welcomes Dr Drew. They discuss COVID-19's impact on the social well being of kids, as well as the media's impact on the virus and what our immediate future looks like in the face of the current pandemic.

Sharon Stone is this week's guest on The Dennissance, where she and Dennis discuss her life's work fighting AIDS and draw comparisons to the current Covid 19 Pandemic. Sharon also touches on the #METOO Movement, social injustices like redlining and profiling, as well as some of her iconic roles in films like Casino, Basic Instinct, and her new Netflix series, Ratched.

In this episode of The Dennissance, Dennis sits down with comedy icon and his co-star from Innerspace, Martin Short, along with the film's director, Joe Dante. During this mini Innerspace reunion, the three discuss how the film came to be, the fun they had on the set, and how it has become a cult classic.

On this episode of The Dennissance, "My Pillow Guy" Mike Lindell joins Dennis for a very candid conversation that covers everything from his crack cocaine addiction and inventing MY PILLOW to how he and Donald Trump became friends.

In this episode, Dennis reconnects with author and screenwriter W. Bruce Cameron, who penned A Dog's Purpose and A Dog's Journey - both of which starred Dennis. They discuss their time spent on set together, their love of Man's Best Friend, and more.

Hall of Fame football player and lifetime advocate for social justice joins Dennis for some candid conversation about the current climate in our country. They discuss the ongoing protests against systemic racism and Jim's involvement in the Civil Rights movement.

Dr Anthony Fauci has been one of the lead members of the Trump administrations's White House Coronavirus task force addressing the Covid-19 pandemic from the very beginning. The career immunologist joins Dennis for a candid and topical conversation around the pandemic, America's response, and what we can expect next.