Biomarkers of aging are indispensable for testing interventions. While promising, the recent focus on molecular aspects should not detract from the functional parameters for which excellent correlation with mortality, and ample clinical human data exist.

The field of biogerontology has established itself through significant lines of research in recent decades. However, despite early breakthroughs, progress in understanding the aging process has been slow. To push the field forward, new methodologies and technologies are likely needed to unravel the complexity of aging. This meeting brought together leading scientists and innovators to explore some emerging approaches, presenting groundbreaking advancements in four key sessions, culminating in a panel discussion.

Knee osteoarthritis (OA) has long been considered as a cartilage disease. However, it is now well established that cartilage defects are the ultimate OA feature only. Several studies investigating the mechanisms of OA onset/progression have recognized the infrapatellar fat pad as an active OA-player but also as a possible source of stem cells with regenerative potential for cartilage. Is it really like that? a cautious approach should be adopted.