Detection and Whole-Genome Sequencing of Carbapenemase-Producing Aeromonas hydrophila Isolates from Routine Perirectal Surveillance Culture

J Clin Microbiol. 2016 Apr;54(4):1167-70. doi: 10.1128/JCM.03229-15. Epub 2016 Feb 17.

Abstract

Perirectal surveillance cultures and a stool culture grew Aeromonas species from three patients over a 6-week period and were without epidemiological links. Detection of the blaKPC-2 gene in one isolate prompted inclusion of non-Enterobacteriaceae in our surveillance culture workup. Whole-genome sequencing confirmed that the isolates were unrelated and provided data for Aeromonas reference genomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aeromonas hydrophila / classification
  • Aeromonas hydrophila / enzymology*
  • Aeromonas hydrophila / genetics*
  • Aeromonas hydrophila / isolation & purification
  • Anal Canal / microbiology*
  • Bacterial Proteins / genetics*
  • Epidemiological Monitoring
  • Feces / microbiology
  • Genetic Variation
  • Genome, Bacterial*
  • Genotype
  • Humans
  • Molecular Epidemiology
  • Sequence Analysis, DNA*
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase
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