CFD in Medicin and Biology
CFD in Medicin and Biology
CFD in Medicin and Biology
Denis Doorly
Imperial College London
Morteza Gharib
California Institute of Technology
Peter Hunter
University of Auckland
Michael Engelman
ANSYS, Inc.
Sunday, March 25, 2012 14:00 17:00 17:00 18:00 18:00 18:15 Arrival and Check-in Welcome Reception Balcony facing the Dead Sea Opening Comments David Elad, Chairman of the conference Dov Litvinoff, Mayor of Tamar Regional Council Vocal Performance Desert Voices Opening Lecture: THE DELICATE DISTINCTION BETWEEN MOLECULAR DYNAMICS AND FUNCTIONAL DISORDER: LESSONS FROM THE DEAD SEA BACTERIA RIBOSOMES Nobel Laureate Prof. Ada Yonath, Weizmann Institute of Science, Israel Dinner Social Hour
Monday, March 26, 2012 07:00 08:00 Breakfast Session I: New CFD Methods Chairman: Robert Nerem, USA Ezra Neufeld, Switzherland 08:00 08:18 CFD SIMULATION IN BIOMEDICAL APPLICATIONS Michael Engelman, ANSYS Inc., USA WAVING RINGS AND SWIMMING IN CIRCLES: SOME LESSONS THROUGH COMPUTATIONAL FLUID DYNAMICS Lisa Fauci, Tulane University, USA TAKING IMAGE-BASED CFD OUT OF THE LAB AND INTO THE CLINICS: APPROACHES, PITFALLS, OPEN-SOURCE SOFTWARE AND THE CLOUD Luca Antiga, Orobix, Srl, Italy LARGE EDDY SIMULATION OF A NOVEL CAVOPULMONARY ASSIST DEVICE FOR FONTAN CIRCULATION Steven Frankel, Purdue University, USA APPLICATION OF LATTICE BOLTZMANN MODELS TO INVESTIGATE MULTISCALE TRANSPORT, MIXING AND DRUG DISSOLUTION IN THE INTESTINE James Brasseur, Pennsylvania State University, USA BUILDING 'BOTTOM UP' BLOOD FLOW COAGULATION MODELS USING MECHANICAL STATISTICS Gilead Moiseyev, Pinchas Bar-Yoseph, Technion, Israel HIGH-RESOLUTION NUMERICAL SIMULATION OF PATIENT-SPECIFIC HEMODYNAMICS WITH IMPLANTED MEDICAL DEVICES Fotis Sotiropoulos, University of Minnesota, USA Coffee Break Session 2: Flow & Transport on the Cellular & Molecular Scale Chairman: Sheldon Weinbaum, USA Jos Spaan, The Netherlands 10:35 10:53 CELLULAR AND MOLECULAR DYNAMICS: MODELING NATURE'S ORCHESTRA Robert Nerem, Georgia Institute of Technology, USA COLLECTIVE CELL GUIDANCE BY COOPERATIVE INTERCELLULAR FORCES Jeffrey Fredberg, Harvard School of Public Health, USA ON INTRA-MEMBRANE CAVITATION AND PRESSURE IN THE MOLECULAR LEVEL Eitan Kimmel, Technion, Israel
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Monday, March 26, 2012 (continued) 11:29 11:47 HOW FORCES REGULATE THE CELL RESPONSE TO THE SURROUNDING ENVIRONMENT? Daniel Isabey, Inserm-CNRS & University Paris Est Crteil, France MECHANOTRANSDUCTION AND THE GLYCOCALYX John Tarbell, City College of the City University of New York, USA MECHANICS OF SOLUTE TRANSPORT THROUGH THE ENDOTHELIAL GLYCOCALYX Herbert Lipowsky, Penn State University, USA ENDOTHELIAL SURFACE GLYCOCALYX AND TUMOR CELL ADHESION IN THE MICROVESSEL Bingmei Fu, City College of the City University of New York, USA Lunch & Free Time Coffee Break FDA Session Chairman:
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MEDICAL DEVICE REGULATION AND THE ROLE OF MODELING STRATEGIES TO AID PRE-CLINICAL TESTING Session 3: Respiratory Flows Chairman: Kerry Hourigan, Australia Kelly Burrowes, New Zealand 16:00 16:18 HOW WELL DOES MODELING INFORM THE PHYSIOLOGY FROM WHICH IT STEMS? Robert Schroter, Imperial College London, UK BIOFLUID MECHANICS OF PULMONARY ATELECTRAUMA Don Gaver, Tulane University, USA UNDERSTANDING RESPIRATORY AIR AND BLOOD FLOW DELIVERY Merryn Tawhai, University of Auckland, New Zealand PARTICLE DEPOSITION & DRUG DELIVERY THROUGH THE LUNG AIRWAY SYSTEM: PATIENT-SPECIFIC OR STATISTICAL APPROACH? Marcel Filoche, Ecole Polytechnique, France EXERCISES IN NATURAL ANATOMICAL VARIATIONS: THE NASAL AIRWAYS Denis Doorly, Imperial College London, UK CFD ON THE NASAL AIRFLOWS: ROLE IN DIAGNOSIS AND SURGERY Sung-Kyun Kim, Seung-Kyu Chung, Konkuk University & Sungkyunkwan University, South Korea TWO PHASE FLOWS IN PULMONARY AIRWAYS James Grotberg, University of Michigan, USA
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Monday, March 26, 2012 (continued) 19:00 20:00 20:00 22:00 Dinner Posters & Social Hour
Tuesday, March 27, 2012 07:00 08:00 Breakfast Session 4: Virtual Prototyping of Medical Devices Chairman: Mory Gharib, USA Idit Avrahami, Israel 08:00 08:18 VASCULAR DEVICE DESIGN AND THE ROLE OF CFD Tim McGloughlin, University of Limerick, Ireland STENT STRUT CROSS-SECTIONAL GEOMETRY: STREAMLINING REDUCES FLOW SEPARATION Juan Jimenez, Peter Davies, University of Pennsylvania, USA FROM VIRTUAL TO RAPID PROTOTYPING AND EXPERIMENTAL VALIDATION: ECMO REDEFINED Ulrich Steinseifer, RWTH Aachen University, Germany QUANTITATIVE COMPARISON OF MECHANICAL BLOOD DAMAGE PARAMETERS IN ROTARY VENTRICULAR ASSIST DEVICES Katharine Fraser, University of Maryland, USA SHEAR STRESS AND VULNERABLE PLAQUE FORMATION Rob Krams, Imperial College London, UK APPLICATION OF THE EULERIAN HEMOLYSIS INDEX METHOD FOR SIMULATING HEMOLYSIS IN PERIPHERAL INTRAVENOUS CATHETER DEVELOPMENT Patrick Downie, Austin McKinnon, Ray Isaacson, BD, USA Coffee Break Session 5: Microfluidic Devices Chairman: Nikos Stergiopulos, Switzerland Joseph Bull, USA 10:20 10:38 MICROFLUIDIC STUDIES OF CANCER METASTASIS Roger Kamm, Massachusetts Institute of Technology, USA MICROFLUIDIC PLATFORM FOR VASCULAR BIOLOGY: ANGIOGENESIS AND ANASTOMOSIS IN MICROFLUIDIC DEVICES Noo Li Jeon, Seol National University, Korea MECHANICS BASED MICROFLUIDIC DEVICEFOR THE DETECTION AND RETRIVAL OF RARE CIRCULATING TUMOR CELLS Chwee Teck Lim, National University of Singapore, Singapore FLUID MECHANICS AND MASS TRANSPORT IN A MICROGRAVITYSIMULATING CELL BIOREACTOR Mian Long, Chinese Academy of Sciences, China MULTIPLE PARALLEL FLOW-CHAMBER FOR SHEAR-DEPENDENT LEUKOCYTES ADHESION ASSAYS Gabriele Dubini, Politecnico di Milano, Italy
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Tuesday, March 27, 2012 (continued) 11:50 12:08 MICROFLUIDIC DESIGNS OF PULMONARY ACINAR NETWORKS: CFD AND EXPERIMENT Josue Sznitman, Technion, Israel Tour to Jerusalem Lunch box on the bus Dinner in Jerusalem
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Wednesday, March 28, 2012 The Elizabeth & Nicholas Slezak Day 07:00 08:00 Breakfast Session 6: Patient Specific & Multi-Scale Modeling Chairman: Mort Friedman, USA Andrea Remuzzi, Italy 08:00 08:17 USING CFD FOR PATIENT SPECIFIC SURGICAL PLANNING IN SINGLE VENTRICLE PATIENTS Ajit Yoganathan, Georgia Institute of Technology, USA TECHNIQUES FOR CARDIAC VALVE REPAIR: SIMULATION OF PATIENT SPECIFIC POSTOPERATIVE SCENARIOS FOR PERSONALIZED SURGICAL PLANNING Alberto Redaelli, Politecnico di Milano, Italy SHEAR STRESS AND ATHEROSCLEROSIS IN HUMAN CORONARY ARTERIES Frank Gijsen, Erasmus Medical Center Rotterdam, The Netherlands PATIENT-SPECIFIC AORTIC VALVE DYNAMIC SIMULATIONS AND PATHOLOGY OF THE ASCENDING AORTIC SEGMENTS Krishnan Chandran, University of Iowa, USA IMAGE-BASED COMPUTATIONAL FLUID DYNAMICS SIMULATIONS IN PATIENT-SPECIFIC VASCULAR MODELS USING THE MIMICS INNOVATION SUITE Patricia Lopes, Erik Boelen, Materialise Group, Belgium A MULTI-SCALE PATIENT SPECIFIC COMPUTATIONAL STUDY TO PREDICT HEMODYNAMICS OF STAGE 2 PALLIATION FOR SINGLEVENTRICLE HEARTS Francesco Migliavacca, Politecnico di Milano, Italy IMAGE-BASED VS. PATIENT-SPECIFIC MODELS: WHAT IS THE DIFFERENCE AND DOES IT MATTER? David Steinman, University of Toronto, Canada Coffee Break Session 7: Cardiovascular Engineering 1 Chairman: Forbes Dewey, USA 10:25 10:42 DESIGN OPTIMIZATION IN BIOFLUID MECHANICS Ross Ethier, Imperial College London, UK INTERFACING BASIC COMPUTATIONAL RESEARCH AND CLINICAL PRACTICE: A VASCULAR ACCESS CASE STUDY Pascal Verdonck, Ghent University, Belgium THREE-DIMENSIONAL NUMERICAL SIMULATION OF BLOOD FLOW IN APOE- /- MICE AORTIC ARCH AROUND ATHEROSCLEROSIS PLAQUES Kerry Hourigan, Monash University, Australia
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Wednesday, March 28, 2012 The Elizabeth & Nicholas Slezak Day (continued)
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CORONARY PERFUSION IN HEALTH AND DISEASE: TRANSLATION FROM PHYSIOLOGICAL MODELS TO CLINICAL PRACTICE Maria Siebes, University of Amsterdam, The Netherlands EMERGING ROLE OF MECHANICAL CIRCULATORY SUPPORT IN THE MANAGEMENT OF ADVANCED HEART FAILURE: SUCCESS, LIMITATIONS AND OPPORTUNITIES Marvin Slepian, University of Arizona, USA WALL SHEAR STRESS AND ATHEROSCLEROSIS; A HETERODOX VIEW Peter Weinberg, Imperial College London, UK WALL SHEAR STRESS AND ATHEROSCLEROSIS: AGE RELATED VARIATIONS IN A STUDY OF RABBIT AORTAS Spencer Sherwin, Imperial College London, UK AORTIC WAVE DYNAMICS AND ITS INFLUENCE ON LEFT VENTRICULAR WORKLOAD Mory Gharib, California Institute of Technology, USA Lunch & Free Time Coffee Break Session 8: Cardiovascular Engineering 2 Chairman: Yacov Shamash, USA
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ISRAELI TECH-INNOVATIONS IN CARDIOVASCULAR MEDICINE THE "START UP' NATION Ran Koronowski, Rabin Medical Center, Israel FLUID DYNAMICS IN CARDIOVASCULAR SURGERY: EXPERIMENTAL MODELING, COMPUTATIONAL SIMULATION AND CLINICAL RELEVANCE Ikuo Fukuda, Hirosaki University School of Medicine, Japan THE ROLE OF LOW SHEAR STRESS RATES FOR PLATELET DEPOSITION Klaus Affeld, Medical University Berlin, Germany BIOMECHANICS AND PLAQUE PROGRESSION IN HUMAN CORONARY ARTERIES Don Giddens, Georgia Institute of Technology, USA OPTIMIZING THE THROMBORESISTANCE OF MECHANICAL CIRCULATORY SUPPORT DEVICES - DEMONSTRATION IN A VENTRICULAR ASSIST DEVICE Danny Bluestein, Stony Brook University, USA FREQUENCY AND DISTRIBUTION OF MICROCALCIFICATIONS IN VULNERABLE PLAQUE AND THEIR ROLE IN FIBROUS CAP RUPTURE Sheldon Weinbaum, City College of the City University of New York, USA
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Wednesday, March 28, 2012 The Elizabeth & Nicholas Slezak Day (continued) 17:22 17:39 MICROCIRCULATORY TRANSPORT INFORMS THE STUDY OF ARTERIAL DISEASE Forbes Dewey, Massachusetts Institute of Technology, USA CONCLUDING REMARKS Shmuel Einav, Tel Aviv University, Israel
th Banquet Dinner + Celebration of Shmuel's 70 birthday Keynote Lecture: THE ISRAELI SPACE INDUSTRY Prof. Daniel Hershkovitz, Minister of Science and Technology, Israel
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Thursday, March 29, 2012 07:00 08:00 Breakfast Session 9: Physiological Flow Modeling 1 Chairman: Patrick Segers, Belgium Alexander Yakhot, Israel 08:00 08:18 A MULTISCALE MODEL OF HYPERACTIVATED SPERM Sarah Olson, Lisa Fauci, Worcester Polytechnic University, USA LEFT-RIGHT PATTERNING IN DEVELOPING EMBRYOS: A CASE OF THEORETICAL PREDICTION FROM FLUID DYNAMICS IN BIOLOGY Oreste Piro, University of Balearic Islands, Spain EMBRYONIC GROWTH APPLICATIONS OF CARDIOVASCULAR FLUID MECHANICS Kerem Pekkan, Carnegie Mellon, USA FSI SIMULATION OF THE VELOCITY PROFILE IN THE HUMAN FETAL DUCTUS VENOSUS Leif Rune Hellevik, Norwegian Institute of Science & Technology, Norway AN INITIAL CORRELATION STUDY OF PULSATILE VENTRICULAR ASSIST DEVICE THROMBUS DEPOSITION BETWEEN EXPERIMENTAL FLUID DYNAMICS AND AN IN VIVO IMPLANT Keefe Manning, Pennsylvania State University, USA QUANTITATIVE COMPARISON OF 4D MRI FLOW MEASUREMENTS TO 3D CFD OF CEREBROSPINAL FLUID MOVEMENT IN THE SPINAL SUBARACHNOID SPACE Bryn Martin, Nikos Stergiopulos, Swiss Federal Institute of Technology (EPFL), Switzerland Coffee Break Session 10: Physiological Flow Modeling 2 Chairman: Ronald Magness, USA Yoram Lanir, Israel 10:20 10:38 INTERSTITIAL FLOW IN THE HIERARCHICAL PORE SPACE ARCHITECTURE OF BONE TISSUE Steve Cowin, City College of the City University of New York, USA SLOW FRICTIONAL FLOW AND ION TRANSPORT WITH EMPHASIS ON CARTILAGE CELLULAR ELECTOMECHANICAL-SIGNAL TRANSDUCTION Van Mow, Columbia University, USA EXPERIMENTAL CHARACTERIZATION OF LYMPHATIC VESSEL MECHANICS AND PUMPING James Moore, Texas A&M University, USA LUMPED-PARAMETER MODELING OF MICROLYMPHATIC VESSELS Chris Bertram, University of Sydney, Australia
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Thursday, March 29, 2012 (continued) 11:32 11:50 COMPUTATIONAL FLUID DYNAMIC MODEL OF FISH FEEDING Roi Holzman, Tel Aviv University, Israel GENERATION AND CONTROL OF FLOW RATE BY A MULTI-PINCHER IMPEDANCE PUMP Moshe Rosenfeld, Tel Aviv University, Israel Tour to Masada Lunch box on the bus Dinner Posters & Social Hour
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COMPUTATIONAL FLUID DYNAMICS (CFD) IN MEDICINE AND BIOLOGY in conjunction with the SEVENTH INTERNATIONAL BIOFLUID MECHANICS SYMPOSIUM Monday (March 26) Poster Presentations
1. AFLUIDSTRUCTUREINTERACTIONMODELOFPHYSIOLOGICPORCINEAORTICVALVEUNDER FULLCARDIACCYCLE GilMarom,TelAvivUniversity,Israel 2. CORRELATIONBETWEENPLAQUECOMPOSITIONANDSHEARSTRESSUSINGTHREE DIMENSIONALRECONSTRUCTEDHISTOLOGYANDCOMPUTATIONALFLUIDDYNAMICSOF DISEASEDHUMANCAROTIDARTERIES JolandaWentzel,ErasmusMC,TheNetherlands 3. SHEARSTRESSDISTRIBUTIONIN3DRECONSTRUCTEDCORONARYBIFURCATIONSBYFUSION OFIVUSANDMSCT FrankJHGijsen,ErasmusMC,TheNetherlands 4. APATIENTSPECIFICMULTISCALESTUDYOFTHENORWOODPROCEDUREINCLUDINGAORTIC COARCTATION:EXPERIMENTALVERSUSCOMPUTATIONALMODELING FrancescoMigliavacca,PolitecnicodiMilano,Italy 5. STATISTICALWSSMAPSINRUPTUREDANDUNRUPTUREDCEREBRALANEURYSMS LeonidGoubergrits,BiofluidMechanicsLaboratory,Charit,Germany 6. NUMERICALSIMULATIONOFBLOODFLOWINFEMORALPERFUSIONWITHCANNULAOR GRAFT TakeshiGoto,HirosakiUniversity,Japan 7. FULLYCOUPLED3DFLUIDSTRUCTUREINTERACTIONSIMULATIONSOFATOTALARTIFICIAL HEART SimonSonntag,RWTHAachenUniversity,Germany 8. CFDEVALUATIONOFTHETHROMBOGENICPOTENTIALOFBLOODRECIRCULATINGDEVICESIN EXTRACORPOREALCIRCULATION. AlessandraPelosi,PolitecnicodiMilano,Italy 9. NOVELAORTICCANNULAFORCARDIOPULMONARYBYPASSTOREDUCECEREBRALEMBOLI ANUMERICALSTUDY IditAvrahami,ArielUniversity,Israel 10. MECHANICALASPECTSOFFENESTRATEDENDOGRAFTSFORTREATMENTOFABDOMINAL AORTICANEURYSM IditAvrahami,ArielUniversitycenterofSamaria,Israel,Israel 11. COMPUTATIONALFLUIDDYNAMICSINBIFURCATEDSTENTEDCORONARYARTERIES GabrieleDubini,PolitecnicoDiMilano,Italy
COMPUTATIONAL FLUID DYNAMICS (CFD) IN MEDICINE AND BIOLOGY in conjunction with the SEVENTH INTERNATIONAL BIOFLUID MECHANICS SYMPOSIUM Monday (March 26) Poster Presentations
12. THEINFLUENCEOFSIMPLIFIEDBOUNDARYCONDITIONSONTHEOUTCOMEOFCFD SIMULATIONSINTHEMOUSEAORTA PatrickSegers,GhentUniversity,Belgium 13. MITRALVALVEANTERIORLEAFLETINVIVOSHAPEMAYCONTRIBUTETOOPTIMIZING VENTRICULAREJECTION MarcoStevanella,PolitecnicodiMilano,Italy 14. REDUCINGTHEDATA:ANALYSISOFTHEROLEOFVASCULARGEOMETRYONBLOODFLOW PATTERNSINCURVEDVESSELS SpencerSherwin,ImperialCollegeLondon,UnitedKingdom 15. TOWARDOPTIMIZINGHEMODYNAMICEFFICIENCYOFTHEFONTANYGRAFTWITHIN ANATOMICCONSTRAINTS ChristopherHaggerty,GeorgiaInstituteofTechnology,USA 16. FLOWDEVELOPMENTPASTBICUSPIDAORTICVALVESANDTHERELATIONSHIPTOASCENDING AORTICPATHOLOGY SarahC.Vigmostad,TheUniversityofIowa,USA 17. EFFECTOFARTERIALWALLHYPERTROPHYANDSTIFFNESSONTHEBLOODFLOWINFLEXIBLE CAROTIDARTERYBIFURCATION JungYulYoo,SeoulNationalUniversity,Korea 18. EXPERIMENTALANDCOMPUTATIONALSTUDIESOFAFORMEDTHROMBUSWITHINA BACKWARDSFACINGSTEPGEOMETRY JoshuaO.Taylor,ThePennsylvaniaStateUniversity,USA 19. CELLFREELAYERANDSHEARSTRESSVARIATIONINMICROVESSELS JunfengZhang,LaurentianUniversity,Canada 20. UNDERSTANDINGWAVEPROPAGATIONPHENOMENAINTHEARTERIALTREE NikosStergiopulos,EPFL,Switzerland 21. MIDDLEMEATALANTROSTOMYANDNASALAIRFLOW:ACOMPUTATIONALFLUIDDYNAMIC STUDY SeungKyuChung,SungkyunkwanUniversitySchoolofMedicine,Korea 22. EFFECTOFARTERIALDISTENSIBILITYANDSTENOSESONPRESSUREDROPINPULSATILEFLOW OrenRotman,TelAvivUniversity,Israel
COMPUTATIONAL FLUID DYNAMICS (CFD) IN MEDICINE AND BIOLOGY in conjunction with the SEVENTH INTERNATIONAL BIOFLUID MECHANICS SYMPOSIUM Thursday (March 29) Poster Presentations
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PERMEABILITYOFTHEPLASMAMEMBRANEINCREASESWITHTHESTRAINLEVELIN STATICALLYSTRETCHEDMYOBLASTS AmitGefen,TelAvivUniversity,Israel BENCHMARKINGOFFLUID/STRUCTUREINTERACTIONMODELSOFWAVEPROPAGATION C.D.Bertram,UniversityofSydney,Australia MEASUREMENTANDMRIMAGINGBASEDSIMULATIONOFTHEMAGNETOHEMODYNAMIC EFFECT EsraNeufeld,FoundationforResearchonInformationTechnologiesinSociety(ITIS), Switzerland PATIENTSPECIFICMULTISCALEHEMODYNAMICCOMPUTATIONALMODELFORPLANNING VASCULARACCESSSURGERYINHEMODIALYSISPATIENTS AndreaRemuzzi,UniversityofBergamo,Italy OSCILLATORYCOUETTEFLOWOFASISKOFLUIDINAROTATINGSYSTEM ShirleyAbelman,UniversityoftheWitwatersrand,SouthAfrica ANALYSISOFNEOROLOGICCOMPLICATIONSDURINGCARDIOPULMONARYBYPASS TimA.S.Kaufmann,RWTHAachenUniversity,Germany WAKEFLOWOFECCENTRICSTENOTICGEOMETRIES KerryHourigan,MonashUniversity,Australia THEOPTICALVIRTUALENDOSCOPYFORVISUALIZATIONOFTHEURINEFLOWINTHE PROSTATICURETHRA TakuroIshii,ChibaUniversity,Japan OPTIMALSWIMMINGGAITOFUNDULATORYSWIMMERSATLOWREYNOLDSNUMBER:THE NEMATODEC.ELEGANS JosueSznitman,TechnionIsraelInstituteofTechnology,Israel EFFECTSOFANASTOMOTICANGLEANDFLOWDIVISIONONDISTURBEDFLOWINRADIAL CEPHALICFISTULAEFORHAEMODIALYSIS BogdanEneIordache,MarioNegriInstitute,Italy ROLEOFSHEARSTRESSFORSURFACTANTPRODUCTIONINAMICROFLUIDICMODELOFFETAL AIRWAYS JannaTenenbaumKatan,TechnionIsraelInstituteofTechnology,Israel AMICROFLUIDICNETWORKFORDRUGSCREENINGWITHSTRONTIUMRANELATEON CULTUREDSAOS2CELLSFOROSTEOPOROSISTHERAPY:DESIGNANDFABRICATION GabrieleDubini,PolitecnicodiMilano,Italy
COMPUTATIONAL FLUID DYNAMICS (CFD) IN MEDICINE AND BIOLOGY in conjunction with the SEVENTH INTERNATIONAL BIOFLUID MECHANICS SYMPOSIUM Thursday (March 29) Poster Presentations
13. ROLEOFCONFINEDJETSONBLOODCLOTTINGWITHININTRACRANIALCEREBRALANEURYSMS S.Cito,UniversitatPompeuFabra,Spain 14. ACOUSTICDROPLETVAPORIZATIONFORGASEMBOLOTHERAPY JosephL.Bull,UniversityofMichigan,USA 15. REVISITINGTURBULENCEINCEREBRALANEURYSMS:ARISKFACTORFORRUPTURE? KristianValenSendstad,UniversityofToronto,Canada 16. CEREBRALARTERYHEMODYNAMICSINPEDIATRICSICKLECELLDISEASE:APRELIMINARY STUDY AmandaK.WakeBuck,VanderbiltUniversity,USA 17. VALIDATIONOFCORONARYPERFUSIONPREDICTEDFROMCUMULATIVEARTERIALLUMEN VOLUME P.vanHorssen,AcademicMedicalCenter,TheNetherlands 18. NUMERICALSIMULATIONOFULTRASOUNDINDUCEDBIOMARKERCAPTURINGINTO LIPOSOMES LuaiR.Khoury,BenGurionUniversityoftheNegev,Israel 19. MIMICKINGPULMONARYACINARFLOWSATTHEMICROSCALEUSINGMICROFLUIDICS RamyFischler,TechnionIsraelInstituteofTechnology,Israel 20. ACUTECHANGESINCORONARYWAVEINTENSITYINPATIENTSUNDERGOING TRANSCUTANEOUSAORTICVALVEIMPLANTATION CristinaRolandi,UniversityofAmsterdam,TheNetherlands 21. DETERMINANTSOFTRANSMURALCORONARYFLOW:MECHANISMSOFSUBENDOCARDIAL VULNERABILITY YoramLanir,TechnionITT,Israel 22. CHANGESINUTERINEARTERYSHEARSTRESSANDBLOODPRESSUREINNORMALPREGNANT VS.PREECLAMPTICWOMEN:EFFECTSOFHIGHALTITUDEANDANCESTRY RonaldR.Magness,UniversityofWisconsinMadison,USA 23. VALVELESSPUMPINGINATHICKWALLELASTICTUBE PavelKozlovsky,TelAvivUniversity,Israel 24. ONAPPLICATIONOFPROPERORTHOGONALDECOMPOSITIONFORANALYZINGBLOODFLOWS INARTERIES AlexanderYakhot,BenGurionUniversity,Israel