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    Bethesda System

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    Joyce Pardo Fernandez
    This document contains 6 figures with descriptions of squamous cellularity in Pap smear samples at different levels from 75 cells to 1400 cells per field at 4x magnification. It provides guidance on the minimum cell counts and number of fields needed to determine if a sample is adequate. It also includes 2 figures showing examples of atypical endocervical cells that were later determined to be pre-cancerous or cancerous conditions.

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    Bethesda System

    Uploaded by

    Joyce Pardo Fernandez
    148 views186 pages
    This document contains 6 figures with descriptions of squamous cellularity in Pap smear samples at different levels from 75 cells to 1400 cells per field at 4x magnification. It provides guidance on the minimum cell counts and number of fields needed to determine if a sample is adequate. It also includes 2 figures showing examples of atypical endocervical cells that were later determined to be pre-cancerous or cancerous conditions.

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    This document contains 6 figures with descriptions of squamous cellularity in Pap smear samples at different levels from 75 cells to 1400 cells per field at 4x magnification. It provides guidance on the minimum cell counts and number of fields needed to determine if a sample is adequate. It also includes 2 figures showing examples of atypical endocervical cells that were later determined to be pre-cancerous or cancerous conditions.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    148 views186 pages

    Bethesda System

    Uploaded by

    Joyce Pardo Fernandez
    This document contains 6 figures with descriptions of squamous cellularity in Pap smear samples at different levels from 75 cells to 1400 cells per field at 4x magnification. It provides guidance on the minimum cell counts and number of fields needed to determine if a sample is adequate. It also includes 2 figures showing examples of atypical endocervical cells that were later determined to be pre-cancerous or cancerous conditions.

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    Figure 1.1.

    Squamous cellularity: This image depicts the appearance of a 4x field of a


    conventional Pap smear with approximately 75 cells. The specimen is unsatisfactory if
    all fields have this lever, or less, of cellularity. It is to be used as a guide in assessing the
    squamous cellularity of a conventional smear. An adequate conventional smear has an
    estimated minimum of approximately 8,000-12,000 well visualized and preserved
    squamous cells.

    Figure 1.2. Squamous cellularity: This image depicts the appearance of a 4x field of a
    conventional pap smear with approximatelly 150 cells. If of fields have this level of
    cellularity, the specimen will meet the minimum cellularity criterion, but by only a small margin.
    Figure 1.3. Squamous cellularity: This image depicts the appearance of a 4x field of a
    conventional pap smear with approximatelly 500 cells. A minimum of 16 fields with
    similar (or greater) cellularity are needed to call th specimen adequate.
    Figure 1.4. Squamous cellularity: This image depicts the appearance of a 4x field of a
    conventional pap smear with approximatelly 1000 cells. A minimum of 8 fields with
    similar (or greater) cellularity are needed to call the specimen adequate.
    Figure 1.5 Squamous cellularity: This image depicts the appearance of a 4x field of a
    conventional Pap smear with approximately 1400 cells. A minimum of 6 fields with
    similar (or greater) cellularity are needes to call the specimen adequate.
    Figure 6.6. Case reported as atypical endocervical cells, NOS (CP). Cluster of cells shows
    crodwing and overlapping of nuclei, nuclear enlargement, chromocenters, and small nucleoli.
    Follow-up showed high-grade cervical intraepithelial neoplasia (CIN).
    Figure 6.7. Atypical endocervical cells, favor neoplastic (CP). Routine screen from a 29-year-old
    woman. Sheet of crowded cells with increased N/C ratios and mitotic activity. Note feathering at
    the edges of the sheet. Follow-up was endocervical AIS.
    FIN

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