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    Madcow and Mad "Human" Disease

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    Maruli Pandjaitan
    Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord.

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    Madcow and Mad "Human" Disease

    Uploaded by

    Maruli Pandjaitan
    72 views15 pages
    Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord.

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    © © All Rights Reserved

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    Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    72 views15 pages

    Madcow and Mad "Human" Disease

    Uploaded by

    Maruli Pandjaitan
    Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 15

    Mad Cow and Mad Human

    Diseases

    By: Alif Rizal Efendi (14210068)

    Bovine spongiform encephalopathy (BSE), commonly


    known as mad cow disease, is a fatal neurodegenerative
    disease in cattle that causes a spongy degeneration in
    the brain and spinal cord. BSE has a long incubation
    period, about 30 months to 8 years, usually affecting
    adult cattle at a peak age onset of four to five years,
    all breeds being equally susceptible. In the United
    Kingdom, the country worst affected, more than
    180,000 cattle have been infected and
    4.4 million slaughtered during the eradication program.

    CreutzfeldtJakob disease or CJD is


    a degenerative neurological disorder (brain disease)
    that is incurable and invariably fatal. CJD is at times
    called a human form of mad cow disease even though
    classic CJD is not related to bovine spongiform
    encephalopathy, however, given that bovin spongiform
    encephalopathy is believed to be the cause of variant
    CreutzfeldtJakob (vCJD) disease in humans, the two
    are often confused.[4]
    Variant CJD (vCJD) is the most common among the types
    of transmissible spongiform encephalopathy found in
    humans. In CJD, the brain tissue develops holes and
    takes on a sponge-like texture. This is due to a type of
    infectious protein called a prion.

    Signs and symptomps :


    The first symptom of CJD is rapidly progressive dementia,
    leading to memory loss, personality changes
    and hallucinations. This is accompanied by physical
    problems such as speech impairment, jerky movements
    (myoclonus), balance and coordination dysfunction
    (ataxia), changes in gait, rigid posture, and seizures.

    Necessary Information :
    A prion is an infectious agent composed of protein in
    a misfolded form. This is in contrast to all other known
    infectious agents (virus/bacteria/fungus/parasite)
    which must contain nucleic acids (either DNA, RNA, or
    both). The word prion, coined in 1982 by Stanley B.
    Prusiner, is derived from the
    words protein and infection.[3] Prions are responsible for
    the transmissible spongiform encephalopathies in a
    variety of mammals, including bovine spongiform
    encephalopathy (BSE, also known as "mad cow
    disease") in cattle and CreutzfeldtJakob disease (CJD)
    in humans. All known prion diseases affect the structure
    of the brain or other neural tissue and all are currently
    untreatable and universally fatal.

    Dementia (taken from Latin, originally meaning "madness",


    from de- "without" + ment, the root of mens "mind") is a
    serious loss of global cognitiveability in a previously
    unimpaired person, beyond what might be expected
    from normal aging. It may be static, the result of a
    unique global brain injury, or progressive, resulting in
    long-term decline due to damage or disease in the body.

    Sources :
    http://en.wikipedia.org/wiki/Mad_cow
    http://en.wikipedia.org/wiki/Creutzfeldt%E2%80%93Jako
    b_disease
    http://en.wikipedia.org/wiki/Prion
    http://en.wikipedia.org/wiki/Dementia

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