Safety Data Sheet

According to EC Directive 91/155/EEC

Date of issue: 20.01.2006
Supersedes edition of 27.11.2003
1. Identification of the substance/preparation and of the company/undertaking
Identification of the product
Catalogue No.: 841132
Product name: (1 S)-(-)--Pinene for synthesis
Use of the substance/preparation
Chemical for synthesis
Company/undertaking identification
Company: Merck Schuchardt OHG * 85662 Hohenbrunn * Germany *
Tel: +49 8102/802-0
Emergency telephone No.: Please contact the regional Merck representation
in your country.
2. Composition/information on ingredients
Synonyms
(1S)-6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane
CAS-No.: 18172-67-3 EC-Index-No.: 650-002-00-6
M: 136.24 g/mol EC-No.: 242-060-2
Formula Hill: C
10
H
16
3. Hazards identification
Flammable. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes and skin.
May cause sensitization by skin contact. Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment. Harmful: may cause lung damage if swallowed.
4. First aid measures
After inhalation: fresh air. Consult doctor if feeling unwell.
After skin contact: wash off with plenty of water. Remove contaminated clothing. Call in physician.
After eye contact: rinse out with plenty of water with the eyelid held wide open. Call in
ophtalmologist.
After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free.
Immediately call in physician.
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Merck Safety Data Sheet
According to EC Directive 91/155/EEC
Catalogue No.: 841132
Product name: (1 S)-(-)--Pinene for synthesis
5. Fire-fighting measures
Suitable extinguishing media:
CO
2
, foam, powder.
Special risks:
Combustible. Vapours heavier than air.
Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
Special protective equipment for fire fighting:
Do not stay in dangerous zone without self-contained breathing apparatus. In order to
avoid contact with skin, keep a safety distance and wear suitable protective clothing.
Other information:
Prevent fire-fighting water from entering surface water or groundwater. Cool container with spray
water from a save distance. Contain escaping vapours with water.
6. Accidental release measures
Person-related precautionary measures:
Avoid substance contact. Do not inhale vapours/aerosols. Ensure supply of fresh air in enclosed
rooms.

Environmental-protection measures:
Do not allow to enter sewerage system; risk of explosion!

Procedures for cleaning / absorption:
Take up with liquid-absorbent material (e.g. Chemizorb ). Forward for disposal. Clean up affected
area.
7. Handling and storage
Handling:
Notes for prevention of fire and explosion:
Keep away from sources of ignition. Take measures to prevent electrostatic charging.
Storage:
Tightly closed in a well-ventilated place, away from sources of ignition and heat. Cool
(below +15C).
8. Exposure controls/personal protection
Personal protective equipment:
Protective clothing should be selected specifically for the working place, depending on
concentration and quantity of the hazardous substances handled. The resistance of the
protective clothing to chemicals should be ascertained with the respective supplier.
Respiratory protection: required when vapours/aerosols are generated. Filter A (acc. to DIN
3181) for vapours of organic compounds
Eye protection: required
The Safety Data Sheets for catalog items are also available at www.chemdat.info Page 2 of 6
Merck Safety Data Sheet
According to EC Directive 91/155/EEC
Catalogue No.: 841132
Product name: (1 S)-(-)--Pinene for synthesis
Hand protection: In full contact:
Glove material: nitrile rubber
Layer thickness: 0.40 mm
Breakthrough time: > 480 Min.
In splash contact:
Glove material: nitrile rubber
Layer thickness: 0.11 mm
Breakthrough time: > 30 Min.
The protective gloves to be used must comply with the specifications
of EC directive 89/686/EEC and the resultant standard EN374, for
example KCL 730 Camatril -Velours (full contact), 741 Dermatril L
(splash contact). The breakthrough times stated above were
determined by KCL in laboratory tests acc. to EN374 with samples of
the recommended glove types.
This recommendation applies only to the product stated in the safety
data sheet and supplied by us as well as to the purpose specified by
us. When dissolving in or mixing with other substances and under
conditions deviating from those stated in EN374 please contact the
supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Other protective
equipment:
Flame-proof protective clothing.
Antistatic protective clothing.
Industrial hygiene:
Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face
after working with substance.
9. Physical and chemical properties
Form: liquid
Colour: colourless
Odour:
pH value not available
Melting point -61 C
Boiling point 164-165 C
Ignition temperature 255 C
Flash point 36 C
Explosion limits lower not available
upper not available
Relative vapour density 4.71
Density (20 C) 0.872 g/cm
3
Solubility in
water immiscible
log Pow 4.53 (calculated) (Lit.)
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Merck Safety Data Sheet
According to EC Directive 91/155/EEC
Catalogue No.: 841132
Product name: (1 S)-(-)--Pinene for synthesis
10. Stability and reactivity
Conditions to be avoided
Heating.
Substances to be avoided
Violent reactions possible with: oxidizing agent.
Hazardous decomposition products
no information available
Further information
light-sensitive, sensitive to air;
explosible with air in a vaporous/gaseous state when heated
11. Toxicological information
Acute toxicity
LD
50
(oral, rat): 4700 mg/kg (External MSDS).

Specific symptoms in animal studies:
Skin irritation test (rabbit): Irritations (External MSDS).

The literature data available to us do not conform with the labelling prescribed by the
EC. The EC has dossiers which have not been published.
Subacute to chronic toxicity
Bacterial mutagenicity: Ames test: negative. (Lit.)
Further toxicological information
After inhalation: Irritations of the mucous membranes, coughing, and dyspnoea. Inhalation may
lead to the formation of oedemas in the respiratory tract.
After skin contact: Irritations. Danger of skin absorption. Risk of skin sensitization.
After eye contact: Irritations.
After swallowing: damage of respiratory tract. Irritations of mucous membranes in the mouth,
pharynx, oesophagus and gastrointestinal tract. After accidental swallowing the substance may
pose a risk of aspiration. Passage into the lung (vomiting!) can result in a condition
resembling pneumonia (chemical pneumonitis).
After absorption of toxic quantities: CNS disorders. Toxic effect on: kidneys.
Further data
The product should be handled with the care usual when dealing with chemicals.
The Safety Data Sheets for catalog items are also available at www.chemdat.info Page 4 of 6
Merck Safety Data Sheet
According to EC Directive 91/155/EEC
Catalogue No.: 841132
Product name: (1 S)-(-)--Pinene for synthesis
12. Ecological information
Behavior in environmental compartments:
Distribution: log Pow: 4.53 (calculated) (Lit.)
An appreciable bioaccumulation potential is to be expected (log Po/w >3).

Ecotoxic effects:
The substance has been classified according to the labelling specified by the EC. The
corresponding data have not been published.

Biological effects:
Toxic for aquatic organisms. May cause long-term adverse effects in the aquatic environment.

Further ecologic data:
Do not allow to enter waters, waste water, or soil!
13. Disposal considerations
Product:
Chemicals must be disposed of in compliance with the respective national regulations. Under
www.retrologistik.de you will find country- and substance-specific information as well as
contact partners.
Packaging:
Merck product packaging must be disposed of in compliance with the country-specific regulations
or must be passed to a packaging return system. Under www.retrologistik.de you will find special
information on the respective national conditions as well as contact partners.
14. Transport information
Road & Rail ADR, RID
UN 1993 ENTZUENDBARER FLUESSIGER STOFF, N.A.G. (PINEN),
3, III, Sondervorschrift 640: E
Inland waterway ADN, ADNR not tested
Sea IMDG-Code
UN 1993 FLAMMABLE LIQUID, N.O.S. (PINENE), 3, III
Ems F-E S-E
Air CAO, PAX
UN 1993 FLAMMABLE LIQUID, N.O.S. (PINENE), 3, III
The transport regulations are cited according to international regulations and in the form
applicable in Germany . Possible national deviations in other countries are not considered.
The Safety Data Sheets for catalog items are also available at www.chemdat.info Page 5 of 6
Merck Safety Data Sheet
According to EC Directive 91/155/EEC
Catalogue No.: 841132
Product name: (1 S)-(-)--Pinene for synthesis
15. Regulatory information
Labelling according to EC Directives
Symbol: Xn Harmful
N Dangerous for the environment
R-phrases: 10-20/21/22-36/38-43-51/53-65
Flammable. Harmful by inhalation, in contact with
skin and if swallowed. Irritating to eyes and skin.
May cause sensitization by skin contact. Toxic to
aquatic organisms, may cause long-term adverse
effects in the aquatic environment. Harmful: may
cause lung damage if swallowed.
S-phrases: 36/37-46-61-62 Wear suitable protective clothing and gloves. If
swallowed, seek medical advice immediately and show
this container or label. Avoid release to the
environment. Refer to special instructions/Safety
data sheets. If swallowed, do not induce vomiting:
seek medical advice immediately and show this
container or label.
EC-No.: 242-060-2 EC label
Reduced labelling (1999/45/EC,Art.10,4)
Symbol: Xn Harmful
N Dangerous for the environment
R-phrases: 10-20/21/22-43-65 Flammable. Harmful by inhalation, in contact with
skin and if swallowed. May cause sensitization by
skin contact. Harmful: may cause lung damage if
swallowed.
S-phrases: 36/37-62 Wear suitable protective clothing and gloves. If
swallowed, do not induce vomiting: seek medical
advice immediately and show this container or
label.
16. Other information
Reason for alteration
Chapter 4: first aid measures.
Chapter 5: fire-fighting measures.
Chapter 8: personal protective equipment.
Chapter 9: change/addition in physical/chemical proprties.
Chapter 10: stability and reactivity.
Chapter 11: toxicological information.
General update.
Regional representation:
This information is given on the authorised Safety Data Sheet
for your country.
The information contained herein is based on the present state of our knowledge. It
characterizes the product with regard to the appropriate safety precautions. It does not
represent a guarantee of the properties of the product.
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