Insulin Chart

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Information based on manufacturer prescribing information and clinical studies. Price information based on Drugstore.com (if available).

Prepared 11/08.

Insulin Comparison Chart
Insulin Name When does it
start working?
(onset)
When will the
effect be the
greatest? (peak)
How long will it
lower blood
glucose?
(duration)
Notes for Use Cost estimate
Rapid Acting
Lispro (Humalog) <15 minutes 0.5-3 hours* 3-5 hours $96 (10 ml vial)
$183 (5x3 ml pen cartridges)
Aspart (Novolog) <15 minutes 0.5-3 hours* 3-5 hours $102 (10 ml vial)
$205 (5x3 ml pen cartridges)
Glulisine (Apidra) <15 minutes 0.5-3 hour* 3-5 hours
If mixing with NPH, rapid acting
insulin should be drawn into syringe
first. Mixture should be given
immediately to avoid effects on peak
action.
$96 (10 ml vial)
$184 (5x3 ml pen cartridges
Short Acting
Regular (Novolin R or
Humulin R)
0.5-1 hour 2-4 hours 4-8 hours May be mixed with NPH in same
syringe. Mixing order should be the
clear regular drawn up first, then the
cloudy NPH (ie clear to cloudy).
$53 (10 ml vial Humulin or Novolin)
$121 (5x3 ml Novolin pen cartridges)
$89 (5x3 ml Innolet cartridges)
Intermediate Acting
NPH (Novolin N or
Humulin N)
2-4 hours 4-10 hours 10-18 hours Available as pen or in vial to be used
with syringe.
$52 (10 ml vial Humulin or Novolin)
$121 (5x3 ml pen cartridges) $91 (5x3 ml
Innolet cartridges)
Long Acting
Glargine (Lantus) 4-6 hours Same action
throughout the
day
24 hours $97 (10 ml vial)
$177 (5x3 ml Solostar pen cartridges)
Detemir (Levemir) 2-3 hours 6-8 hours Dose-dependent
5.7-23.2 hours
Do not mix with other insulins.
Available as pen or in vial.
Duration (clinical trial data):
6 hrs (0.1 U/kg), 12 hrs (0.2 U/kg),20
hrs (0.4 U/kg), 23 hrs (0.8 U/kg and
1.6 U/kg)
$95 (10 ml vial)
$182 (5x3 ml pen cartridges)
Combinations
Humulin or Novolin
70/30
0.5-1 hour 2-10 hours 10-18 hours 70% NPH +30% regular insulin.
Insulin action includes 2 peaks (1
from each formulation).
$54 (10 ml vial)
$135 (5x3 ml pen cartridges) $94 (5x3 ml
Innolet cartridges)
Novolog Mix 70/30
Humalog Mix 75/25 or
50/50
<15 minutes 1-2 hours 10-18 hours Novolog Mix:
aspart protamine 70% + aspart 30%
Humalog mix:
75/25=75% lispro protamine + 25%
lispro
50/50=50% lispro protamine + 50%
lispro
Insulin action includes 2 peaks (1
from each formulation).
Humalog Mix 75/25:
$102 (10 ml vial),
$174 (5x3 ml pen cartridges)

*variable onset simplified to 0.5-3 for ease of learning. Onset may vary between products for each patient.

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