NIOSHTIC-2 Literature Online , a database of the National Occupational Safety and Health system (http://www.cdc.gov/nioshtic-2/default.asp)) on 12/16/2014 Records downloaded: 1 Search Request: [20035749] IN *. ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ NN: 20035749 TI: Asthma and respiratory symptoms in hospital workers related to dampness and biological contaminants. AU: Cox-Ganser-JM; Rao-CY; Park-J-H; Schumpert-JC; Kreiss-K SO: Indoor Air 2009 Aug; 19(4):280-290 LT: http://dx.doi.org/10.1111/j.1600-0668.2009.00586.x AB: The National Institute for Occupational Safety and Health investigated respiratory symptoms and asthma in relation to damp indoor environments in employees of two hospitals. A cluster of six work-related asthma cases from one hospital department, whose symptoms arose during a time of significant water incursions, led us to conduct a survey of respiratory health in 1171/1834 employees working in the sentinel cases hospital and a nearby hospital without known indoor environmental concerns. We carried out observational assessment of dampness, air, chair, and floor dust sampling for biological contaminants, and investigation of exposure-response associations for about 500 participants. Many participants with post-hire onset asthma reported diagnosis dates in a period of water incursions and renovations. Post-hire asthma and work-related lower respiratory symptoms were positively associated with the dampness score. Work-related lower respiratory symptoms showed monotonically increasing odds ratios with ergosterol, a marker of fungal biomass. Other fungal and bacterial indices, particle counts, cat allergen and latex allergen were associated with respiratory symptoms. Our data imply new-onset of asthma in relation to water damage, and indicate that work-related respiratory symptoms in hospital workers may be associated with diverse biological contaminants. KW: Biohazards; Biological-effects; Biological-monitoring; Breathing; Bronchial-asthma; Environmental-exposure; Environmental-health; Epidemiology; Exposure-assessment; Exposure-levels; Exposure-methods; Humidity; Indoor environment; Indoor-air-pollution; Indoor-environmental-qua lity; Inhalation-studies; Occupational-exposure; Occupational-health; Occupational-respiratory-disease; Pulmonary-congestion; Pulmonary-function; Pulmonary-system; Pulmonary-system-disorders; Respiratory-hypersensitivity; Respiratory-infections; Respiratory-irritants; Respiratory-system-disorders; Statistical-analysis; Work-environment; Worker-health; Work-performance; Work-practices; Author Keywords: Building-related asthma; Indoor environmental quality; Mold; Ergosterol; Healthcare workers; Dampness AD: JM Cox-Ganser, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Field Studies Branch, Division of Respiratory Disease Studies, M/S 2800, 1095 Willowdale Rd, Morgantown, WV 26505 CD: INAIE5 DP: 20090801 DT: Journal Article
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Jcoxganser@cdc.gov 2009 1 89277078 DRDS Indoor Air WV; MT