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The following information was generated from the


NIOSHTIC-2 Literature Online ,
a database of the National Occupational Safety and Health system
(http://www.cdc.gov/nioshtic-2/default.asp)) on 12/16/2014
Records downloaded: 1
Search Request: [20035749] IN *.
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NN: 20035749
TI: Asthma and respiratory symptoms in hospital workers related to
dampness and biological contaminants.
AU: Cox-Ganser-JM; Rao-CY; Park-J-H; Schumpert-JC; Kreiss-K
SO: Indoor Air 2009 Aug; 19(4):280-290
LT: http://dx.doi.org/10.1111/j.1600-0668.2009.00586.x
AB: The National Institute for Occupational Safety and Health investigated
respiratory symptoms and asthma in relation to damp indoor environments
in employees of two hospitals. A cluster of six work-related
asthma cases from one hospital department, whose symptoms arose
during a time of significant water incursions, led us to conduct
a survey of respiratory health in 1171/1834 employees working
in the sentinel cases hospital and a nearby hospital without
known indoor environmental concerns. We carried out observational
assessment of dampness, air, chair, and floor dust sampling for
biological contaminants, and investigation of exposure-response
associations for about 500 participants. Many participants with
post-hire onset asthma reported diagnosis dates in a period of
water incursions and renovations. Post-hire asthma and work-related
lower respiratory symptoms were positively associated with the
dampness score. Work-related lower respiratory symptoms showed
monotonically increasing odds ratios with ergosterol, a marker
of fungal biomass. Other fungal and bacterial indices, particle
counts, cat allergen and latex allergen were associated with
respiratory symptoms. Our data imply new-onset of asthma in relation
to water damage, and indicate that work-related respiratory symptoms
in hospital workers may be associated with diverse biological
contaminants.
KW: Biohazards; Biological-effects; Biological-monitoring; Breathing;
Bronchial-asthma; Environmental-exposure; Environmental-health;
Epidemiology; Exposure-assessment; Exposure-levels; Exposure-methods;
Humidity; Indoor environment; Indoor-air-pollution; Indoor-environmental-qua
lity;
Inhalation-studies; Occupational-exposure; Occupational-health;
Occupational-respiratory-disease; Pulmonary-congestion; Pulmonary-function;
Pulmonary-system; Pulmonary-system-disorders; Respiratory-hypersensitivity;
Respiratory-infections; Respiratory-irritants; Respiratory-system-disorders;
Statistical-analysis; Work-environment; Worker-health; Work-performance;
Work-practices;
Author Keywords: Building-related asthma; Indoor
environmental quality; Mold; Ergosterol; Healthcare workers;
Dampness
AD: JM Cox-Ganser, Centers for Disease Control and Prevention, National
Institute for Occupational Safety and Health, Field Studies Branch,
Division of Respiratory Disease Studies, M/S 2800, 1095 Willowdale
Rd, Morgantown, WV 26505
CD: INAIE5
DP: 20090801
DT: Journal Article

EA:
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Jcoxganser@cdc.gov
2009
1
89277078
DRDS
Indoor Air
WV; MT

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