Sem1 Ospe
Sem1 Ospe
You notice that your friend Sam, a diligent and organized student lately seemed to be in
such an indifferent mood. He/she was noted to be always late in attending lectures, did not
participate in SGD sessions and reduced his contributions in PBL sessions. You are
worried as a friend and concerned because his/her behaviour is affecting his/her studies.
The end of semester examination is ahead.
You decided to approach and talk to Sam after the SGD session.
1.
2.
You have 4 minutes to plan your approach in this current station and another 4 minutes to
perform the task in the next station.
SCENARIO
You are known as a diligent and organized first year medical student. You recently showed
signs of indifference to your studies like always coming late during lectures and minimal
to non-participation in PBL and SGD sessions. Your changes were noticed by an SGD
group member (the student candidate). After an SGD session, the student candidate will
approach you and try exploring the reasons of your behavioural changes and expressing his
/her concern.
The Setting
You are sitting in the SGD room and staring into space.
Your Task
When the bell rings (at the end of every 4 minutes the student had spoken to you), indicate
your impression on the students performance by showing the mark to the examiner:
Rating by Sam
1 mark
2 marks
The student attempting but unable to make you change your mind
3 marks
This is a histologic picture of the submandibular gland. What do you call the structure at
the tip of the pointer?
The graph above shows the activities of two different enzymes, one adapted to work in the
stomach and the other adapted to work in the pancreas.
1. What is the pH optimum for both enzymes?
2. Why is the pH optimum different?
3. What will happen to the enzyme as the pH rises?
1 mark
2 marks
2 marks
Station
1. What are the major contaminants in DNA extracts?
2. How do you determine the purity of DNA extracted?
3. What are the applications of DNA isolation in medicine?
1 mark
2 marks
2 marks
Station
1. Explain the principle of serum proteins electrophoresis.
2. Mention two major causes of hypoalbunaemia.
3. Explain the mechanism of edema in hypoalbunemia.
2 marks
1 mark
2 marks
Station
1. What is a reference solution?
2. State TWO (2) differences between the reference and a sample.
3. Explain why the spectrophotometer is set to read zero absorbance
(100% transmission) with the reference solution in place.
2 marks
1 mark
2 mark
10
Station
1. Mention two indications for Glucose tolerance test.
2. diagnose GDM ( gestational diabetes mellitus )
3. impared glucose tolerance
1 mark
4. How G6PD enzyme protects erythrocytes haemolysis?
5. produce NADPH reduce glutathione ( antioxidants )
6. reduction methaemaglobin
2 marks
7. Why red blood cells are being used for the detection of G6PD deficiency?
8. - no mito
9. produces fluroscene if contain G6PD 2 marks
11