ENT Clinical Treatment Guidelines (Rwanda) 2012
ENT Clinical Treatment Guidelines (Rwanda) 2012
ENT Clinical Treatment Guidelines (Rwanda) 2012
CONDITIONS
OF THE NOSE
MINISTRY OF HEALTH
P. O. Box 84 Kigali
www.moh.gov.rw
September 2012
ENT CLINICAL TREATMENT GUIDELINES
01
Foreword
Dr Agnes Binagwaho
Minister of Health
Kigali-Rwanda
04
Contents
ACCRONYMS........................................................................3
1.
CONDITIONS
OF THE NOSE
3.
NECK MASSES....................................................................61
4.1. Chronic cervical lymphadenopathy.......................................61
4.2. Parapharyngeal Abscess..........................................................62
4.3. Parotid tumour.........................................................................64
4.4. Submandibular tumour...........................................................66
4.5. Goitre.........................................................................................67
REFERENCES.................................................................................69
ACCRONYMS
CBC: Complete Blood Count
CONDITIONS
OF THE NOSE
CONDITIONS
OF THE NOSE
C HA P TE R 1
CONDITIONS OF
THE NOSE
CONDITIONS
OF THE NOSE
-- Predisposing factors
Allergy
Polluting environment e.g. Dust, fumes
Overuse of nasal decongestants (Rhinitis medicamentosa)
Hormone imbalances : e.g. During pregnancy,
puberty, Hormone Replacement Therapy (HRT), hormonal contraception
Signs and symptoms
-- Nasopharyngeal discomfort
-- Dry cough
-- Headache
-- Running nose
-- Fever
-- Watery eyes
-- Allergic rhinitis presents with a triad of symptoms; sensation of nasal obstruction, sneezing and watery running nose
ENT CLINICAL TREATMENT GUIDELINES
-- Pharyngitis
-- Laryngo-bronchitis
Investigations
-- Full Blood Count
Cetrizine
12 years of age: 5 mg - 10 mg per day
Children 6 to 11 years: 5 mg - 10 mg
once daily depending on symptom severity
CONDITIONS
OF THE NOSE
OR
Oracefal (cefadroxyl): 1gx2/day/10days in adults and 50mg/
kg/day in children divided into two doses for children.
OR
Zinnat (cefuroxime): 500mg to 1g every 12 hours for at
least 10 days
10
Recommendations
-- Caution should be taken when associating nasal decongestants containing pseudo- ephedrin in hypertensive
patient
CONDITIONS
OF THE NOSE
4.3. Ozena
Definition: It is a chronic inflammation of nose characterized by atrophy of nasal mucosa including the glands, turbinate
bones, and the nerve elements supplying the nose.
Causes
-- Infection
-- Idiopathic
Signs and symptoms
-- Nasal foul smell
-- Crusting
-- Septum perforation/ulcers
Investigations
-- Nasal swab for lab analysis to identify associated microbes
Management
-- Restoration of nasal hydration by irrigation with normal
saline
-- Surgical treatment
11
4.4. Epistaxis
Definition: It is a nose bleeding
Causes
-- Local (trauma, inflammation, foreign bodies, tumours of the
nose and rhinopharynx, Iatro
genic)
-- Systemic (cardiovascular diseases, bleeding disorder, liver diseases, kidney diseases, febrile diseases)
-- Idiopathic (unknown)
Signs and symptoms
-- Blood coming from the nose or the rhinopharynx
Investigations
-- Full blood count
-- Clotting profile
-- Nasal endoscopy
12
Non Surgical
Clean blood clots from the nose
Application of cold compresses on the nose
Direct pressure applied by pinching the soft fleshy
part of the nose applied for at least five minutes and up
to 20 minutes
Topical antibiotics Ointment to the nasal mucosa has
been shown to be an effective treatment for recurrent
epistaxis
CONDITIONS
OF THE NOSE
Tetracycline Ointment
Topical vasoconstrictor;
Surgical
Chemical Cautery of the bleeding site with silver
nitrate or 20% of solution trichlor acetic acid under
topical anaesthesia
Electro coagulation
Arterial ligation
Embolisation
13
14
CONDITIONS
OF THE NOSE
Surgical treatment
Surgery of the polyps is indicated after failure of the
medical treatment
Recommendation
-- Always send the biopsy specimen for Histopathology
examination
Complications
-- Deformation of the nasal pyramid
-- Perforation of the nasal septum
-- Septicemia
15
-- Antibiotics
Cloxacillin PO 50-100mg/kgx3/day/8days for children and
500-1g x 3/day/8 days for adults.
Recommendations
-- Early septal reconstruction in children in order to prevent immediate and late facial deformity and nasal dysfunction
-- Immediately drain the septal abscess as soon as the patient
presents
-- Keep the nasal pack as long as the collection is present
-- Otitis media
16
Management
-- Removal of the foreign body
CONDITIONS
OF THE NOSE
Recommendations
-- Proper setting, proper lighting, proper equipment and a
cooperative patient are all important
-- Foreign body in the nasal cavity is an emergency
17
18
CONDITIONS
OF THE EAR
C HA P TE R 2
CONDITIONS OF
THE EAR
19
20
Causes
CONDITIONS
OF THE EAR
Definition: It is an inflammation of the middle ear cavities lasting less than 3 weeks
-- Viral
-- Predisposing factors include poor living conditions, adenoids, sinusitis, allergic rhinitis, tonsillitis, asthma, Cranial
facial abnormalities, etc
Signs and symptoms
-- Fever
-- Vomiting
-- Otalgia
-- Otorrhea
-- Impaired hearing
-- Hearing impairment
ENT CLINICAL TREATMENT GUIDELINES
21
Management
-- Elimination of predisposing or risk factors
Pharmacological treatment
First choice treatment
Amoxicillin, Po 1000mgx3/day/10-14 days for adults;
50mg-100mg/kg day/10-14 daysinj children
Otrivine(Xylometazoline)1% nose drops x2/day/ 5 day
maximum for adults. Then for children use Otrivine 0.5%
nose drops
Alternative treatment
Amoxicillin+clavuranic acid (amoxiclav) Oral, 625mgx3/
day/8-10 days in Adults; Syrup x 3 weight graduation/day/1014 days in children
OR
Oracefal (cefadroxyl): 1gx2/day/10days for adults and
50mg/kg/day divided into two doses for children
OR
Zinnat (cefuroxime): tabs 250mg x2/day/7days
Surgical Treatment
Myringotomy and sometimes ventilating Tube insertion
Surgical treatment of complications
Recommendation
-- Patients representing with recurrent Acute Otitis media should
be referred to an ENT specialist
22
Causes
-- Inadequate management of otitis media
CONDITIONS
OF THE EAR
-- Intracranial complications
Lateral sinus thrombophlebitis
Brain abscess
Otitic hydrocephalus
Meningitis
Investigations
-- Pus Cultures
-- Audiogram
-- CT-scan
23
-- Trauma
Signs and symptoms
-- Discomfort , Itching and Pain in the ear
-- Ear discharge
-- Septicemia
24
CONDITIONS
OF THE EAR
Pharmacological treatment
Topical Anti-Microbial
Terra cortryl ointment local application
renewable every two days until symptoms
subside
Candiderm cream local application
renewable every two days for 10 days
Systemic Antibiotic
Cloxacillin PO 500mg x3/day/7days in
adults and 50-100mg/kg/day divided in 3
doses in children
Ciprofloxacine 500mg x 2/day (In cases
of malignant Otitis externa) until bone scan
becomes normal
Anti- Inflammatory
Ibuprofen PO 400mgx3/day/5days for
adults; 200mgx3/day/5days in children
Recommendations
-- In cases of persistent otitis externa. Refer the patient to an
ENT specialist
25
26
CONDITIONS
OF THE EAR
Predisposing factors
-- Secondary stenosis
Management
Non-pharmacological treatment:
Removal of foreign body
If a foreign body is alive (e.g. insects) has to be
killed with cooking oil or warm water by suffocation as
an emergency before removal
Pharmacological treatment:
First choice treatment
Removal of foreign body by; syringing using warm
water or specific instruments under general anesthesia
for children or uncooperative patients
Brufen + Terra cortryl ointment local application
renewable every two days for 6 days, + Amoxicillin tabs
or syrup (if infection or trauma)
27
2 . 6. Impacted wax
Definition: Its a condition in which ear wax has become tightly
packed in the external ear canal to the point that the canal is blocked
Cause
-- Idiopathic
Predisposing factors: include pushing wax deeper when cleaning the
outer ear with a cottontipped applicator.
Signs and symptoms
-- Hearing loss
-- Hearing impairment
Management
-- Removal of impacted wax by syringing
-- Medical treatment if necessary
28
Alternative treatment
Cerulyx topical ear drops to loosen the impacted wax
CONDITIONS
OF THE EAR
29
30
2 . 8. Presbycusis
Cause
-- Physiological
CONDITIONS
OF THE EAR
31
2 . 9. Acute Mastoiditis
Definition: It is an acute and sudden infection of the mastoid cells following an infection of the middle ear cavity.
Cause
-- Bacterial micro-organisms always spreading from middle ear
cavity infection (Acute otitis media)
Signs and symptoms
-- Fever
-- In some instances, the ear on the affected side seems pushed out
and quite prominent due to collection of pus in the mastoid bone.
-- Suppurative otitis media
-- Headache
-- Hearing loss
Complications
-- Extra-cranial complications:
Facial paralysis
Neck abscess
Septicemia
Labyrinthitis
-- Intra-cranial complications:
Extradural abscess
Subdural abscess
Brain abscess
Meningitis
Otitic hydrocephalus
Investigations
-- Pus culture
32
CONDITIONS
OF THE EAR
Paracetamol PO 500mgx3/day/5-7days
in adults; 15mg/kg/dose x 3/5-7days in
children
Ant-inflammatory
Brufen PO 400mgx3/day/5days for
adults; 200mgx3/day/5days in children
Alternative treatment
Amoxicillin + claviranic acid iv 40mg/kgx3/
day/10days (Max) for Adult
Cefotaxime iv 50 -100mg/kg x3/day/7-10 days (for
Children)
Ceftriaxone iv 50mg/kg once daily
Surgical treatment
Incision of abscess and drainage
Myringotomy
Mastoidectomy .This is done in cases of antibiotic
therapy.
Recommendation
-- Refer the suspected or confirmed case of acute mastoiditis
to an ENT surgeon.
33
34
CONDITIONS
THE PHARYNX
C HA P T E R 3
CONDITIONS OF
THE PHARYNX
35
36
3. CONDITIONS OF THE
PHARYNX (THROAT)
3 . 1. Adenotonsillar hypertrophy
Definition: It is an exaggerated hypertrophy of adenoid and
palatine tonsil tissues that may affect normal breathing.
CONDITIONS
THE PHARYNX
Cause
-- Nasal voice
-- Adenoid faces
-- Snoring
-- Sleep apnea
-- Growth retardation
-- Diabetis
-- Obesity
Investigation
-- X-ray of rhino pharynx (lateral view)
Management
Surgery treatment
Surgery - Adenoidectomy plus tonsillectomy under
general anesthesia
ENT CLINICAL TREATMENT GUIDELINES
37
-- Fungal infection
Signs and symptoms
-- Pain on swallowing (odynophagia)
-- Fever, chills
-- Foul smell
-- Headache
-- Rheumatic fever
-- Acute glomerulonephritis
-- Septicemia
-- Bronchitis or pneumonia
-- Rheumatic heart disease
-- Septic arthritis
Investigations
-- Swab for laboratory analysis
-- complete blood count,
-- streptococcal screen
38
CONDITIONS
THE PHARYNX
39
3 . 3. Peritonsillar abscess
Definition: It is collection of pus in the peritonsillar space.
Cause
-- Complication of a local or pharyngeal infection
Signs and symptoms
-- Acute sore throat
-- Trismus
-- Halitosis
-- Neck abscesses
40
CONDITIONS
THE PHARYNX
Alternative
Clindamycin iv 10 mg 500mg/kg x4/day/3-4 days,
and thereafter, oral, 10 mg 500mg/kg x3/day/3-4days
Amoxillin+Clavuranic acid PO 625mgx3/day/6days
Recommendation
-- Tonsillectomy done one Month after medical treatment
for recurrent to Peritonsillar abscess
41
3 . 4. Retropharyngeal abscess
Definition: Severe complication of upper respiratory tract infections
common in children less than 3 years of age
Causes
-- Spread of nasopharyngeal infection to retro- pharyngeal lymphnodes
Signs and symptoms
-- Torticollis
-- Soar throat
-- Drooling
-- Stridor
-- Dyspnea
-- Dysphagia
-- Lethalgia
-- Dehydration
Complications
-- Pneumonia
-- Mediastinal abscess
-- Neck abscesses
-- Brain abscess
-- Septicemia
-- Pericarditis
Investigations
-- CBC(complete blood count)
-- Lateral neck X-ray
42
Pharmacological treatment
First choice treatment
Anti-Inflammatory
Diclofenac 75 mg IMx 2/day/5days
Antibiotics
CONDITIONS
THE PHARYNX
Surgical
Incision and drainage of abscess under general
anesthesia
43
3 . 5. Pharyngitis
Definition: It is a diffuse inflammation of the mucous membrane lining the pharynx
Causes
-- Viral infection
-- Bacterial infection
-- Chronic rhino-sinusitis
Signs and symptoms
-- Sore throat (is the main complaint)
-- Fever and Chills
-- Headache
-- Redness of the mucous membrane lining the pharynx sometimes pus exudates,
-- edema of uvula
-- Dysphagia
Complications
-- Blockage of the airway (in severe cases)
-- Middle ear infections
-- Rheumatic fever
-- Acute glomerulonephritis
-- Septicemia
-- Bronchitis or pneumonia
-- Rheumatic heart disease
-- Septic arthritis
44
Management
Pharmacological treatment
First choice treatment
Amoxicillin, Po 1000mgx3/day/8 days for adults;
50mg-100mg/kg day/8 days Amoxicillin syrup
250mg/5ml, 50-100mg/kgx3/day/8days for children
Ibuprofen 400mgx3/day for 5 days, Child; ibuprofen
5-10mg/kgx3/day/5 days
Antiseptics; Adult: hextril, betadine or sonatec guagings x2-3/day for 5days.
CONDITIONS
THE PHARYNX
Alternative treatment
Amoxicillin+clavuranic acid (amoxiclav) Oral,
625mgx3/day/8 days in Adults; Syrup x 3 weight
graduation/day/8 days in children
OR
Oracefal (cefadroxyl): 1gx2/day/8days for adults and
50mg/kg/day divided into two doses for children
OR
Zinnat (cefuroxime): tabs 250mg x2/day/7days
Recommendations
-- Pharyngitis due to virus should be treated conservatively.
-- Gastro-oesophageal reflux disease should be treated with
proton-pump inhibitors (like omeprazol) and referred to
internal medicine
45
3 . 6. Oropharyngeal candidiasis
Definition: It is a diffuse inflammation of the mucous membrane lining the oral cavity and pharynx due to candida albicans.
Causes/predisposing factors
-- Candida albicans
-- Immunocompromised patients
Signs/symptoms
-- Painless, white patches in the mouth and pharynx
-- Pain and difficulty swallowing
Complications
-- Esophagitis
-- Gastro-enteritis
-- Meningitis
-- Endocarditis
-- Arthritis
-- Endophthalmitis
Investigations
-- KOH preparation of scraping from mucosal surface
Management
-- Management of associated disease
Pharmacological treatment:
First choice treatment
Nystatin
Oral tablets, 100,000 unitsx3/day/14 days,
Oral suspension, 1 to 2 teaspoons, held in
mouth for 5 min and then swallowed
OR
Itraconazole: Capsules or oral solution. 100 mg Pox4/day or
x2/day for 2 weeks
46
3 . 7. Tumours of naso-pharynx
CONDITIONS
THE PHARYNX
-- Environmental factors
-- Unknown
-- Predisposing factors include problems with the bodys immune system, alcohol, genetic factors, smoking etc
Signs and symptoms
-- Purulent rhinorrhoea
47
-- Sleep apnea
Complications
-- Severe hemorrhage which can lead to shock and death
-- Loco-regional and distant metastasis
Investigations
-- Nasal fibroscopy
-- Arteriography
48
-- Airway obstruction
-- Persistent dyspnea
CONDITIONS
THE PHARYNX
-- Wheezing
-- Pneumothorax
-- Pneumonia
-- Lung consolidation
-- Abscess
Investigation
-- X-ray of the chest
Management
Non-pharmacological treatment
Hospitalization of the patient
First aid management (Heimlich manoeuvre or Moffeson manoeuvre for children under 8 months)
49
-- Hematemesis
50
CONDITIONS
THE PHARYNX
Management
Recommendation
-- Transfer the patient to an ENT surgeon
-- Dysphagia
51
-- Sore throat
Complications
-- Asphyxia and death may occur
-- Septic shock
-- Edema of larynx
-- Pneumonia
-- Meningitis
-- Pneumothorax
-- Epiglottis abscess
Investigations
-- Direct inspection using laryngoscope under anesthesia
-- Neck X-ray
Management
-- Letting the child be in a position of comfort
-- Immediate hospitalization
52
3 . 11. Laryngotracheobronchitis
(subglottitis)
Causes
-- Viral infection (common cause)
-- Bacterial infection
CONDITIONS
THE PHARYNX
-- Barking cough
-- Fever
-- Dysphonia
-- Sore throat
Complications
-- Airway obstruction
-- Septicemia
-- Sub-glottis Stenosis
-- Toxic shock
-- Cardio-respiratory arrest
-- Pneumonia
53
Management
Non-pharmacological treatment:
Make the child as comfortable as possible
Avoid agitating the child with unnecessary procedures and
examinations
Maintenance of the airway
Pharmacological treatment
First choice Treatment
Intubation or tracheotomy to maintain airway
Ampicillin iv 50-100mg/kgx4/day/10days with Gentamycine iv 3-5mg/kgx2/day/5days
Hydrocortizone iv 0.1-1 mg/kgx3/day/3-5days
Anti-nflammatories: Brufen syrup in children; Paracetamol
tabs in adults
Alternative treatment
Amoxicillin + claviranic acid iv 40mg/kgx3/day/7-10days
Cefotaxime iv 50-100mg/kg x3/day/7-10 days
Recommendation
-- High index of suspicion start patient on treatment and transfer
to an ENT surgeon for further management of the airway
Laryngeal Trauma
Definition: It is an injury of the larynx, which may be penetrating or
blunt
Causes
-- Motor vehicle accident (MVA)
54
-- Exsanguination
-- Asphyxia and death may occur immediately
CONDITIONS
THE PHARYNX
Complications
-- Laryngeal stenosis
-- laryngeal CT examination
-- MRI
-- Angiography
55
Recommendation
-- High index of suspicion and clinical judgment should guide
transfer to an ENT surgeon for further management
3 . 12. Laryngomalacia
Definition: It is a very common condition of infancy, in which the soft,
immature cartilage of the upper larynx collapses inward during inhalation, causing airway obstruction
Causes
-- Congenital
-- Idiopathic
56
CONDITIONS
THE PHARYNX
Non-pharmacological treatment
Condition is usually self limiting
Reassuring family members of favorable prognosis
Position adjustments (Propped up position)
Pharmacological treatment
Supplemental oxygen should be administered in case
significant hypoxemia
Surgical management
Tracheotomy in severely affected infants
Supraglottoplasty
57
58
C HA P T E R 4
NECK MASSES
NECK MASSES
59
60
4. NECK MASSES
4.1. Chronic cervical lymphadenopathy
Definition: It refers to nodes that are abnormal in size, consistency or number
Causes
-- Infection of the head, neck, sinuses, ears, eyes, scalp,
pharynx
NECK MASSES
-- Lymphoma
61
-- Surgical
62
-- Odynophagia
-- Trismus
-- Sore throat
-- Torticollis (rare)
-- Suppurative Mediastinitis
NECK MASSES
Complications
-- Sepsis
-- Neck cellulitis
Investigations
-- Needle aspiration of pus for confirmation of abscess and
sent for lab analysis
-- Ultrasound over the mass safe and less traumatic
63
64
-- CT- scan
-- Histopathology exams
Management
Pharmaceutical
Chemotherapy+/- Radiotherapy indicated in advanced disease or where surgery is not indicated.
NECK MASSES
Surgery removal
Total or superficial parotidectomy is the mainstay of
treatment
Recommendations
-- Refer patients with parotid tumors to ENT department.
-- Open biopsy is CONTRAINDICATED.
65
-- Ultra-sound
-- MRI
-- CT- scan
-- Histopathology exams
-- Chest X-ray
Management
-- Medical
-- Support treatment
Analgesics like Paracetamol 500 mgx3/day 5 days
66
4.5. Goitre
Definition: It is an enlargement of the thyroid gland which can
be seen as a swelling in the front
of the neck.
Types
-- Diffuse small goiter: The whole thyroid gland swells. When
touched it feels smooth
-- Nodular goiter: Certain parts of the thyroid gland - nodules - swell. The gland may feel lumpy when touched
Causes
-- Idiopathic
NECK MASSES
67
-- Histology
-- Scintigraphy
Management
Pharmacological treatment
Levo-thyroxine, 100g/day in case of total thyroidectomy
Surgical
Thyroidectomy (total or partial)
68
REFERENCES
1. Cummings CW, Flint PW, Haughey BH, et al. Otolaryngology: Head & Neck Surgery. 4th ed. St Louis, Mo; Mosby;
2005:3019-3020.
2. Mandell GL, Bennett JE, Dolin R. Principles and Practice
of Infectious Diseases. 6th ed. London: Churchill Livingstone;
2005:771.
3. Nasal septal abscess in children: from diagnosis to management and prevention; Int J Pediatr Otorhinolaryngol. 2011
Jun; 75(6):737-44. Epub 2011 Apr 14.
4. http://www.nhs.uk/Conditions/Rhinitis---non-allergic/
Pages/Treatment.aspx
5. Gleeson M, et al: Scotts-Brown Otolaryngology Head and
Neck Surgery, 7th Ed.(3 volumes), Hodder Arnold
6. Dhigra PL: Diseases of the Ear Nose and Throat. 4th Edition, Elsevier India
7. Ludman H, Wright T. Diseases of the ear. 6th Edition,
Hodder Arnold
8. http://www.waent.org/archives/2009/vol2-2/20091002larynx-trauma/larynx-trauma.htm
9. Bailey BJ, et al. Head and Neck Surgery Otolaryngology.
4th Edition, Lippincott Williams & Wilkins
LIST OF PARTICIPANTS
No
FAMILY NAME
FIRST NAME
TITLE
DR KAYITESI
BATAMULIZA
ENT SURGEON
DR SENDEGEYA
AUGUSTIN
ENT SURGEON
DR TWAGIRUMUKIZA
EUGEN
ENT SURGEON
DR MUNYARUGAMBA
PROTAIS
ENT SURGEON
DR MUNYAMPUNDU
HORATIUS
NDAYAMBAJE
THEOGENE
PHARMACIST
DR NZEYIMANA
BONAVENTURE
PUBLIC
HEALTH
FACILITIES
EXPERT
DR MANZI
EMMNUEL
QI/ADVISOR
AHABWE
MOSES
TECHNICAL
ADVISOR
10
ATWINE
JOY
QI/SENIOR
TECHNICAL
ADVISOR
11
BUTARE
RICHARD
QI/TECHNICAL
ADVISOR