Biotechnology in Korea 2013

1.
The Past, Present and Future of Korea

06 Korean Miracle
10 General Status
14 Political Changes
2. The History of Science and Technology in Korea

18 The History of Science and Technology of Korea
20 The 30-Year-History of Biotechnology
22 Governmental Investment
23 Bioindustry
3. Competitiveness of Korea in Biotechnology

28 Competitiveness in Science and Technology
30 Large Pool of R&D Experts
31 High-Quality Infrastructure for Clinical Trials
33 Intensification of Industrial Competitiveness
35 Emerging of Successful Biotech Companies
36 Governmental Strong Promotion Policy
4. Bio-Clusters in Korea
40 Major Bio-Clusters
5. Biotech Leading Entities in Korea

50 Status of Biotech & Healthcare Business of
Large-sized Companies
52 Biotech Companies
54 Major Research Institutes
56 Organizations & Associations
57 Clinical Trial Centers & CROs
The Past,
Present and
Future
of Korea
Korean miracle
Korea transforms from Recipient to Donor

Korea joined the Development Assistance Committee of the OECD in
November 2009, becoming the first country to go from aid recipient to donor
since the organizations birth.
Fourth High Level Forum on aid Effectiveness (Busan, Republic of Korea, 29
November-1 December 2011).
Fifty years ago, the scene in Busan, South Korea, would have been a familiar image of
international aid : sacks of grain stacked precariously on a crumbling dockside. The
backdrop would have been a country emerging from war and dependent on outside
assistance to meet the most basic needs. But when national and development leaders
gather in Busan this week to discuss the future of aid, they will see a very different
place : the fifth-busiest commercial port in the world, transporting advanced
technologies around the globe. This, writ small, is the Korean miracle - the
transformation of a country from aid-dependent to aid donor.
(By Tony Blair, The Washington Post Published : November 26, 2011)
The G20 Seoul Summit

The 2010 G20 Seoul Summit was the fifth meeting of the G-20 heads
of government, to discuss the global financial system and the world
economy, which took place in Seoul, South Korea on November 11-12,
2010. Korea was the first non-G7 nation to host a G-20 Leaders
Summit.
Korea, which has succeeded in developing economy, overcoming economic
crises and acting as a mediator between advanced countries and emerging
ones, suggested an agenda* regarding emerging countries, not advanced ones.
* Ensuring global economic recovery, Development issues, Strengthening the international financial
regulatory system, Global financial safety nets, Framework for strong, sustainable, and balanced global
growth, etc.
The G20 has dealt with global issues in depth since it was first held in washington after the 2008
global financial crisis. Now it has been realized as the new driving force behind global economy.
Korea has showed leadership at the summit, stressing the need for trade liberalization, and as a
result has been the first non-G7 Asian country to hold the summit.
Koreas trade volume reaching $1 trillion

Notwithstanding worldwide economic crisis, Korea recorded one-trillion-dollar trade
volume two years in a row, 2011 and 2012, and has been one of eight trade giants.
Korea has achieved it 63 years after establishing its government in 1948, or 50 years after
formulating the export-driven policy under the Five-Year Economic Development Plan in 1962. In
particular, it is the first time a developing country has achieved it.
More noteworthy is that Korea made it two years in a row despite worldwide economic slowdown.
As a result, it has been ranked 8th in the world in terms of trade volume by moving up one pace
from the last time.
Biotechnology in Korea 2013
The world s third largest economic territory occupied with FTAs
IT-based cultural power, The Korean Wave (Hallyu)
Korea s geographic territory was divided into South and North, but its economic
territory has been being expanded with FTAs going to effect with 45 countries.
The Korean wave refers to the phenomenon of Korean entertainment and popular culture
rolling over the world with pop music, TV dramas, and movies. Also known as Hallyu
in Korean, the term was first coined by the Chinese press in the late 1990s to describe the
growing popularity of Korean pop culture in China.
In addition to Korea-US FTA that went into effect in 2012, Korea has entered into FTAs
with EU, Chile, Singapore, EFTA, ASEAN and Peru and thus has built up a global
network that connects Europe, Asia and Americas.
Moreover, 7 countries including Turkey, Canada and Mexico initialed FTAs with
Korea. Since FTAs lead to the robust trade in goods and services, there has been
increasing interest in world-class human resources.
Economic territory means a commingling of geographic territory, other party to FTA and GDP.
The Korean Wave began with TV dramas and K-pop, but now with the development of internet
and social media such as YouTube, Twitter and Facebook a greater variety of cultural contents are
provided in real time throughout Europe and Americas. The Korean Wave has entered upon a new
phase.
The Korean style (K-Style), dominated by K-pop and TV dramas, has recently been
accepted in various parts such as pure art, law and institution and social control system
Popular music, or K-pop : Due to the relatively small size of the Korean music market, songs are
usually released onto YouTube for overseas consumption
Dramas, or K-dramas : Translated into English and other foreign languages by fans, often within
24 hours of release
Language : The increasing interest in Korean language classes since 2009 has been attributed to
the popularity of K-pop songs and K-dramas
Animated comics and films, Cuisine
* Source : Korea International Trade Association (KITA)
FTAs that took effect or negotiations have been concluded as regards 10 cases (47 countries) ;
Negotiations that are underway as regards 6 cases (16 countries) ; FTAs are in the preparation
stage as regards 9 cases (21 countries), as of June 26, 2012.
Economic Situation
General Status
On the basis of Koreas recovery from the global financial crisis, the government has
been continuously making efforts to strengthen the groundwork for long-term growth and
boost the real economy.
Thanks to the governments successful policies, the Korean economy posted a growth rate of 3.6
percent in 2011, and per capita income returned to the US$ 20,000 level.
Facts about Korea

Strategically located at the crossroads of Northeast Asia, Korea is neighbored
by China to the west, Japan to the east, and the Russian Far East to the north.
General
Country Name
Republic of Korea (South Korea)
Language
Korean (Writing system: Hangeul)
Capital City
99,720 sq km
Currency
won (US$ 1 = 1,112.5 won) (as of 2013.3.18)
Population
People
Seoul
Territory
Illiteracy Rate
Life Expectancy
Religion
Political System
Government
0% (people aged between 20 and 40)

50,004,441
* Foreign Residents
(including short-term sojourners) : 1.2 million
Male, 77 years ; female, 83.8 years (2009)
Buddhism (24%), Protestantism (23%), Catholic (8%),
Others (0.8%), Religionless (44.2%)
Republic with a president elected to a single 5-year term
by direct popular vote
Division of power among the executive, legislature
(unicameral National Assembly), and judiciary branches
President
Park Geun-hye since 2013
Suffrage
Universal at 19 years of age
Gross Domestic Product

Per Capita GNI
Economy
Major Industrial Products
Domestic demand has led the growth while private consumption and facility investment have
posted excellent figures. Exports have increased in line with a rise in overseas demand amid the
global economic recovery and backed by increased competitiveness of Korean products. Korea has
leapt ahead to become worlds No. 7 exporting nation, and achieved a trade surplus of over US$40
billion for the second year in a row.
KOSPI (The Korea Composite Stock Price Index) is the index of all common stocks
traded on the Stock Market Division - previously, Korea Stock Exchange - of the Korea
Exchange.
KOSPI, started at 122.52 point on January 4, 1983, reached 1997.05 point at the end of 2012 and
thus increased by over 15 times (1,530%) in 30 years.
The number of companies listed on KOSPI increased by over 2 times (from 334 to 784) in 30
years, and the total market value increased by 34,873.4% (from 3.3-trillion won to 1.1543quadrillion won).
Stock Price Index
(KOSPI, Closing Price)
Mar. 13, 2013
Mar. 14, 2013
Mar. 15, 2013
Mar. 18, 2013
1999.34
2002.13
1986.50
1968.18
US$ 1,116 billion (2011)

US$ 22,489 (2011)
GDP Growth Rate: 3.6% (2011)
Semiconductors, automobiles, ships, consumer
electronics, mobile telecommunications, equipment,
steel, and chemicals

11
Information and Communications
Driving force
Science and Technology
To reinvigorate the development of advanced science and technology, the
government established the Korea Institute of Science and Technology (KIST) and
the Ministry of Science and Technology (MOST) in 1966 and 1967, respectively.
In 2013 Ministry of Science, ICT and Future Planning (MSIP) has been created
to the effect that it takes charge of services regarding research, development,
information and communication and builds up the foundation of creative
economy based on creative science.
The National Science & Technology Commission (NSTC) was launched in April of
2011, and is in charge of establishing the National Science &Technology Basic Plan
and coordinating and connecting trans-governmental science &technology policies
based upon the plan.
Initially, Koreas national science and technology policies focused mainly on the
introduction, absorption, and application of foreign technologies. In the 1980s, however,
emphasis shifted to the planning and conducting of national R&D projects to raise the
level of scientific and technological skills. This included programs to increase both
public and private sector R&D investment and to nurture highly skilled R&D
manpower.
Korea is a leader in the area of information and communications technology (ICT). This
is demonstrated by its vast ICT-related production and exports, world-class technology,
and the wide use of internet and mobile communication devices in the country.
ICT industry-related products, such as computer chips and mobile phones, account for over 33%
of Koreas total exports. As for communications services, nearly every Korean owns at least one
mobile phone. Moreover, almost every household has a broadband connection. All sectors of
industry from the food-service industry to public transportation are heavily dependent on
computers and ICT.
Today, Korean semiconductors, mobile handsets, TFT-LCDs and other items have become the
most coveted in the global market because of their high quality.
Korea has been ranked 1st among 34 OECD countries in wireless broadband penetration rate
(2012). Switzerland and Korea continue to top the OECD ranking for fixed and wireless
broadband respectively.
Mobile broadband has experienced healthy growth (18%) in the last 12 months, largely driven by continuing
strong demand for tablets and smartphones. The average penetration in the OECD area is 56.6 subscriptions
per 100 inhabitants, for a total number of nearly 700 million subscriptions (698.6 million). Korea (104.2) and
Sweden (101.8) top the table, being the only two countries with more wireless broadband subscriptions than
inhabitants.
Since the early 1990s, the government has been concentrating on three areas: fostering
research in the basic sciences, securing an efficient distribution and use of R&D
resources, and expanding international cooperation. These efforts are intended to
increase Koreas technological competitiveness.
South Korea was ranked 22nd among 59 countries and regions in the 2012 global competitiveness
rankings by the Switzerland-based International Institute for Management and Development
(IMD).
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
Overall Competitiveness
32
31
27
32
29
31
27
23
22
22
- Economic Performance
33
41
38
36
49
47
45
21
25
27
- Government Efficiency
33
32
28
41
31
37
36
26
22
25
- Business Efficiency
37
25
27
38
38
36
29
27
26
25
- Infrastructure
26
24
20
22
19
21
20
20
20
20
14
17
13
10
24
14
14
18
14
14
* Scientific Infrastructure
* Tech. Infrastructure
* Source : OECD broadband statistics, 2013.2
* Source : IMD The World Competitiveness Yearbook , 2012
13
The Park Geun-hye government s policy on science & technology
Political Changes
President Park Geun-hye,

Korea s first female president
Park Geun-hye was inaugurated as the Korea s first female president on
February 25, 2013.
The administrative vision of President Park Geun-hye s new government is A new era
of hope and happiness .
The five Administrative Goals of the government are a jobs-centered creative
tailored employment and welfare
creativity-oriented education and
economy
cultural enrichment
a safe and united society and strong security measures for
sustainable peace on the Korean Peninsula
The Park Geun-hye administration plans to create a trustworthy, clean, and capable
government through carrying out these goals, related strategies, and tasks.
Reorganization of Executive Branches : The Korean government was

expansively reshuffled into 17 ministries, 3 sub-ministries and 17 services.
Ministry of Science, ICT and Future Planning (MSIP) and Ministry of Oceans and
Fisheries (MOF) have been newly established to create the future growth engine and
more jobs, and a new position, the Deputy Prime Minister of Economic Affairs, has
been made to overcome the global economic crisis and derive economic revival.
Ministry of Knowledge Economy and Ministry of Public Administration and Security
were reorganized into Ministry of Trade, Industry & Energy and Ministry of Security
and Public Administration respectively. The position, Minister for Special Affairs, was
eliminated, and Korea Food and Drug Administration was upgraded to Ministry of Food
and Drug Safety under the Office of the Prime Minister.
Increase of national R&D expenditure up to 5% of GDP by 2017

National R&D expenditure (includes private sector) will be increased up to 5% of GDP by 2017
(4.03% as of 2011). Basic researches will account for about 40% of national R&D expenditure by
2017 (35.2% as of 2012).
The creative reform of the national R&D system

The national R&D system will be reformed so that it may go through due formalities (basic
development and applied research
commercialization). The intellectual property of
science
creative and versatile talent will be protected through an intellectual ecosystem (creation application - protection).
Creative industries will be promoted through a new fusion technology combined between
brainware and national welfare technology
The investment will be expanded in R&D in order to protect people s welfare,
life, health, property and environment and to improve the quality of their
lives. New industries such as brain nano-bio and brain nano-eco will be
fostered, and brainware-based soft power technology will be promoted.
The Ministry of Science, ICT & Future Planning (MSIP) was launched
MSIP will be creating new added value, new jobs and new growth engines
that are imperatively necessary for the nations sustained growth.
Minister of Science, ICT and Future Planning
15
The History of
Science and
Technology
in Korea
Korea s total R&D expenditure reaches 50-trillion won, inclusive of the

private sector, which is the sixth largest amount in the world.
Notwithstanding worldwide economic crisis, R&D activities in Korea are
on an upward trend and the investment increased by 13.8% from last year.
The History of Science and

Technology in Korea
In 2011 it reached 49.8904-trillon won, which accounts for 4.03% of GDP and ranked
2nd in the world.
In the past 40 years the Korean government, in cooperation with private
organizations, has concentrated on technological catch-up; specifically, it has
introduced overseas advanced technologies and created added value from them.
In recent times, however, its catch-up strategy has rapidly changed to the firstmover strategy.
(Unit : KRW 100 million)
With economic development started in the 1960s, Korea began to recognize the
importances of science and technology, since then it has promoted them at national
level.
In 1966, Korea Institute of Science and Technology (KIST) was founded with a view to
domestically develop technologies necessary for industrial development.
In 1967 Ministry of Science and Technology, an independent body to lead the
promotion of science and technology, was created, and moreover Science and
Technology Promotion Act was enacted in 1967, as a part of legal mechanism that
promotes basic science and technology.
Korea has been investing heavily in six promising new technologies (IT, NT, BT, ST,
ET and CT) since 2000.
The Korean government has been investing heavily in promising new

technologies (6T), especially in IT and BT that are expected to have great
ripple effects and create new markets.
In 2011 the IT sector comprised the highest percentage (19.4%) of the governments
R&D budget, followed by BT (19.0%), ET (16.6%) and ST (5.2%).
Strategy
Catch-up
The percentage of the BT sector has been steadily rising, with an increase in investment in the
biotech industry, new drug development and medical industry.
Innovation
IT : 18.3% (2009)
1960s
S&T Policy
Direction
Key
Industries
Leading
Sector
1970s
1980s
1990s
2000s
Promoting R&D
Enhancing technology innovation
Developing technologies
for key export industries
Developing technologies
for high-tech industries
Developing basic and

fundamental technologies
Labor-intensive
industries
(shoes, bags, etc.)
Government-funded research institutes(GRIs)
Steel, machinery,
vessels and electronics
Hi-tech industries
(semiconductors, cell
phones, vehicles, etc.)
Private enterprises, GRIs, Universities
19.4% (2011), BT : 17.7% (2009)
18.6% (2010)
19.0% (2011)
2010s
Building R&D infrastructure
Natural resources
such as iron one
and tungsten
18.9% (2010)
Electronic & cutting-edge products,

Media /Entertainment
Private enterprises, GRIs, Universities
The History of Science and Technology in Korea
19
The 30-Year History of

Biotechnology in Korea
The National Framework Plans for Promotion of Biotechnology, a

government-wide master plan aimed at the development of national
biotechnology, was prepared to provide the policy direction and guidelines.
Bio-Vision 2016, which established the direction of the development of Korea s
biotechnology over a 10-year period up until 2016 and it was published to achieve a goal
of making Korea a biotechnology leader, according to a vision of realizing a sound
Health life and creating an Prosperous Bioeconomy
Enacting Biotechnology Support Act in 1983, Korea began to

promote biotechnology. In 1994 it established the first National
Framework Plan for Biotechnology (Biotech 2000) and a
nationwide policy and began to invest heavily in R&D.
In 2004, biotechnology (Novel Biomedicine and Organs) was selected as one of
the next-generation growth engines. A pan-governmental agency comprehensive
plan known as The 2nd national framework plan for biotechnology promotion
(Bio-Vision 2016) was established in 2006. The BT Committee under the
National Science & Technology Commission has been operating since 2008.
The second stage plan of Bio-Vision 2016 was established in 2012. Thus active
support policies have been promoted to make biotechnology a growth engine
for future national economic growth.
Vision
Health life and Prosperous Bioeconomy
- Joining the Group of Global Top 7 Biotechnology Nations Objectives
Category
2005
2010
No. of science-technology papers published (National ranking)
13th
11th
7th
14th
15th
13th
2016
Competitiveness in patented technology (National ranking)

Bioindustry*
KRW 2.7 trillion KRW 6.1 trillion KRW 23 trillion
Industrialized market value
Pharmaceutical Industry** KRW 12.5 trillion KRW 19 trillion KRW 26 trillion
* The bioindustry is estimated to grow 22.5% every year for 3 years (2007~2009).
** The pharmaceutical market (production + import - export) is estimated to grow 5.5% every year for 3 years (2008 2010).
21
Governmental Investment
Korea has been strategically promoting the biotechnology sector

emerged as a solution to the problems of aging, environment and
energy, by strengthening investments for securing the original
technologies and industrial infrastructure.
In biotechnology R&D, the Korean government s investment began to increase
conspicuously from the 1990s and has rapidly increased so far since 1994 when the
1st National Framework Plan for Promotion of Biotechnology was established.
The investment exceeded 2 trillion won in 2009 and reached 2.58 trillion won in 2011.
The investment increased by 21% per year between 2002 (451.5 billion won) and 2011
(2.58 trillion won).
Bioindustry
The biotech market in Korea has been continuously growing, with the
increase in production. In particular, the biopharmaceuticals industry has
the highest market share.
In 2011, the bioindustry in Korea has made up a market of 7,542 billion won (production
+ import). It has grown roughly 15.4% every year, when considering 2008 when it
recorded 5,658.9 billion won.
The output of the bioindustry in Korea reached 3,159 billion won in 2006 and 6,160 billion
won in 2010, and so it increased twice in 5 years. At the same time, import is on a decreasing
trend.
In recent 3 years (2008~2010) its output has increased by 16.8%, which is remarkably higher than that of the
manufacturing industry (4.8%).
In 2010 the bioindustry in Korea made 2,744.5 billion won in exports, and the increase in
exports is expected to continue with state support.
The exports increased by 12.1% from 2009 (2,447.4 billion won) ; especially, the biofood industry
showed an increase of 25.8% from last year.
The investment in biotechnology is made by 6 ministries including Ministry of

Science, ICT and Future Planning (MSIP), Ministry of Health & Welfare (MW),
Ministry of Agriculture, Food and Rural Affairs (MAFRA) and Ministry of
Trade, Industry & Energy (MOTIE) and relevant agencies to lead technical
development.
In 2011, MSIP accounted for the highest percentage (37%) of the investment, followed by
MAFRA (includes Rural Development Administration, and Korea Forest Service ; 26.9%),
MOTIE (includes Small and Medium Business Administration ; 19.2%) and MW (11.9%).
* Source : Ministry of Trade, Industry and Energy (2012)
23
The number of biotech companies in Korea is 913, including 221

venture companies and 158 technically innovative companies in
Korea.
As of October 2012, a total of 57 companies have been listed on KOSDAQ,
most of which have gone public since 2000. It well shows that the biotech
industry in Korea has rapidly prospered in recent times.
Year
No. of Companies
Employees
Export
Import
2006
794
17,316
13,502
9,354
2007
834
20,236
14,715
10,208
2008
851
20,520
19,038
11,469
2009
853
22,817
27,287
13,292
2010
913
32,004
27,445
13,816
* Source : Ministry of Trade, Industry and Energy (2012)
Biotech companies in Korea are mostly focusing on the development and

production of biopharmaceuticals and biofoods.
In 2010, biopharmaceuticals and biofoods accounted for 78% (39.3% and 38.5%
respectively) of the total output of the bioindustry, followed by biochemicals (10.2%),
bioenergy and bioresources (4.1%) and bioassay, bioinformatics and R&D service
(2.6%).
We are develops a vision to

become seventh in the world
in biotechnology
Source : Ministry of Trade, Industry and Energy (2012)
Competitiveness
of Korea in
Biotechnology
The remarkable growth of patents in biotechnology in terms of quantity as

well as quality.
Competitiveness in Science
and Technology
Patents from Korea in biotechnology registered in US have been continuously increased

in number ; a total of 453 registrations between 2011 and 2012.
Korea has been ranked 14th in the world in technology strength (TS) that shows the quantitative
and qualitative levels of patents.
Publication capacity of papers from Korea in biotechnology is

rapidly growing every year, and quality of papers is also increased
upon publishing in highly prestigeous international journals.
The technology competitiveness of Korea in biotechnology ranked 10th in the world
(as of 2012) in terms of publications of scientific papers, and has been rapidly and
quantitatively increased since national biotech promotion was started in 1994.
In particular, the number of publications as of SCI Expanded have continuously
increased in number; 420 cases in 1994 (ranked 29th), 2,875 cases in 2002 (ranked
15th) and 8,082 cases in 2012 (ranked 10th).
Year
1994~1997
1998~2001
2002~2005
2006~2010
2011~2012
No. of Patents
48
178
208
523
453
TS Index Ranking
17th
15th
16th
16th
14th
* Analysis : Korea Institute of Patent Information, 2013
Patents in the area of antibody, biomedicine and transgenic animals and plants have been
relatively increasing in terms of quantity and quality.
Technology strength based on patents has recently been growing by 10.9, 6.5 and 4.9 times in the
area of antibody, biomedicine and transgenic animals and plants, respectively.
Technology strength in biomedicine, bioprocess and biometric diagnosis scored 59.66, 15.04 and
11.10, respectively, and showed high levels of performances.
Technology Classification
* Analysis : Biotech Policy Research Center, 2013
The remarkable growth of paper publications in terms of quantity as well as quality.

Papers from Korea, published in world-renowned scientific journals such as Nature,
Science and Cell (NSC), have been increasing in number, more than 60% of which refer
to biotechnology. During last five years (2008~2012), 222 papers have been published
on NSC (18th in the world).
2002 ~ 2005
2011 ~ 2012
Increase
(b/a)
TS(a)
Ranking
TS(b)
Ranking
Bioprocess
10.71
12
15.04
10
1.4 Times
Sensors / Diagnostics
10.97
17
11.10
17
1.0 Times
Proteomics
1.64
17
1.93
15
1.2 Times
Animal & Plant Cell Culture
1.26
17
2.58
14
2.0 Times
Biological Resources / Bioprospection
1.51
14
3.01
2.0 Times
Genomics
3.78
15
4.01
19
1.1 Times
Antibody
0.38
13
4.15
10.9 Times
Enzyme Engineering
1.76
16
2.36
12
1.3 Times
Bio-Pesticide Development
2.52
13
0.43
20
0.2 Times
Transgenic Animals & Plants
0.25
19
1.22
13
4.9 Times
Year
01
02
03
04
05
06
07
08
09
10
11
12
Biomedicines
9.20
22
59.66
10
6.5 Times
NSC publications total
14
19
13
18
29
28
26
28
38
47
44
43
Environmental Biotechnology
8.07
1.86
11
0.2 Times
BT- related NSC publications total 11
11
11
10
23
18
19
15
21
28
25
22
BT ratio (%)
* Analysis : Korea Institute of Patent Information, 2013
78.6 57.9 84.6 55.6 79.3 64.3 73.1 53.5 55.2 59.5 56.8 51.2

Competitiveness of Korea in Biotechnology
29
Large Pool of R&D Experts
With the governmental strong supporting policy, high-quality

human resources in biotechnology have highly been promoted.
Biotechology requires high-quality experts. The number of human resources in
Biotechnology in Korea 2013 (based on the number of graduates from
biotechnology-related departments at the college level and over) was 52,811 in
2012.
Human resources in biotechnology have continuously been increasing, as the bioindustry
has been growing. Among graduates in Korea, the percentage of biotechnology majors
increased from 7.01% in 2007 to 8.33% in 2012.
In particular, Master s or Ph.D. degrees make up more than 20% of the whole group.
~
High-Quality Infrastructure for

Clinical Trials
Korea has succeeded in meeting the international standard of clinical
trials on new drugs, and made an achievement of being the world top 10
in clinical trials, which came from its 10 years of effort.
In 2000 when multinational clinical trials have been allowed, only 5 cases of
multinational clinical trials were conducted in Korea. In 2012, however, 303 cases were
conducted. During last 10 years, Korea marked a 60 times increase in multinational
clinical trials.
The website of global clinical trials (http://clinicaltrials.gov/) shows that Korea has been ranked
6th overall in clinical trials, 4th in single-country trials, and 15th in multinational trials (by total
protocols). Now Seoul is recognized as the world s best city in clinical trials and has been the
mecca of clinical trials in Asia (by sites).
Phase I clinical trials, a national competitiveness indicator, have considerably increased from 19
cases in 2011 to 32 cases in 2012.
The Korea Food & Drug Administration (KFDA) approved 670 cases of clinical trials in
2012, which is a 33.2% increase from 2011 (503 cases).
Such results might come from multinational and domestic pharmaceutical companies expanding
investment and from expanded infrastructure for clinical trials in Korea. The biggest reason why
Korea has recently been emerged as the hub of multinational clinical trials is in that it satisfies fast
progression, high quality and high efficiency.
The number of industrial human resources in domestic biotech companies was

32,004 in 2010, which was 30% higher compared to the previous year. Among
these human resources in bioindustry, 11,329 were for manufacturing, 11,091
were for research and 9,584 were for sales or management.
Meanwhile, the distribution of human resources in domestic bioindustry has shown
more research people than manufacturing people, but the number of manufacturing
people exceeded research people in 2009. It might be considered that demand for human
resources in manufacturing has greatly increased compared to that in research as
bioindustry in Korea is moving to commercialization from research.
* Source : KFDA, 2013
31
Noticing the importance of global clinical trials, the Korean

government began to pave the way early in 2000.
Investigational New Drug (IND) Application and Good Clinical Practice (GCP)
were introduced in 2002 to strengthen the global competitiveness in clinical
trials and to secure subjects safety.
In addition, KoNECT was established in December 2007 with wholehearted support
from the Korean government, academics and related industries in order to meet the
increasing demands for clinical trials and to raise national competitiveness by fostering
necessary human resources, developing core technologies, and building a solid
infrastructure to become a global clinical trial hub.
The CRO industry in Korea has evolved since 2000. In 2007, however, the
industry advanced into a growth phase. The 2014 sales estimates for CROs in
Korea are projected at 440.7 billion KRW.
Contract research organizations (CROs) in Korea increased in number between 2001
and 2004. There are currently 18 domestic CROs and 15 foreign-owned ones in Korea.
Considering population, infrastructures, legal environments, government control and

cost, FierceCRO appointed 7 countries including Korea, Singapore, Taiwan,
Philippines, Argentina, Colombia and Poland, as emerging CRO markets
South Korea (FierceCRO, an article dated of September 10, 2012)

The worlds eyes have been on fast-growing BRIC markets for several years now. In
the CRO sphere, however, BRIC might be rebranded as BRICK: Brazil, Russia, India,
China and Korea. One only has to look at statistics to realize how big a player
South Korea has become in the outsourcing game. The number of new clinical trials
there increased to 513 in 2009 from 206 in 2006, making for a 150% spike over four
years, according to CROAsia.
Thats usually not an accident, Lewis said of the dramatic increase. Its a conscious
decision from a government to do that. One government initiative is KoNECT, a
collaboration between the South Korean government and global CRO Quintiles to
provide life sciences groups with clinical research resources, training and support.
Intensification of Industrial
Competitiveness
Korea has been producing copy drugs (the 1980s) and generic drugs (the
1990s) on the strength of the governments positive supports and
pharmaceutical companies efforts. Entering the 21st century, Korea
succeeded in developing new drugs with new substances and has been
competitive in new drug development in a relatively short space of time.
19 new drugs have been developed so far. In addition, 8 generic drugs, 30 vaccines and 6
drugs based on natural products (plant extracts) have been approved.
The recent success and performance in biotechnology made Korea the 8th country to develop the
H1N1 vaccine (Green Cross, 2009) and first to develop stem cell therapy products (FCB
Pharmicell, 2011).
In 2009 when H1N1 is spreading throughout the world, all the countries in the world keenly competed for the
vaccine. However, Korea could overcome the crisis by using self-developed vaccine.
In Korea, 37 pharmaceutical companies, which have been concentrating on R&D

activities, have 467 pipelines regarding new drugs, generic drugs, biobetters and
biosimilars. New drugs account for the highest percentage (51%, 238) of research
activities, followed by generic drugs (43%, 200) and biosimilars (5.4%, 25).
They can be classified into 18 as to target diseases, inclusive of anticancer drugs, anti-obesity
drugs, central nervous system (CNC) drugs, immuno-regulatory drugs, etc.
South Korea boasts short lead times for new trials; startups there are among the
quickest in Asia, Icon says. The countrys well-tuned regulations and Institutional
Review Board codes offer a firm legal foundation. And its healthcare infrastructure is
solid, too. Goh says Icon works with Korean and non-Korean clients there on all
aspects of drug development, from regulatory consulting work to Phase III trial
management.
Korean clients tend to be well-informed and very clear on their drug development
strategies, Goh says. They have ambitious targets that are focused on the European
and U.S. markets.
* Source : Korea Drug Research Association, 2012
33
Annual growth of approved clinical trials on biotherapeutics was 21% between

2007 and 2011.
Recombinant therapeutics accounted for 63% of the clinical trials, and cell therapy or
gene therapy products are continuously increasing.
In case of biosimilars, 7 domestic pharmaceutical companies carry out clinical trials for
8 products.
Plasma
Recombinant Cell
Gene
Vaccines Anti-toxins
Derivatives
Therapeutics Therapy Therapy
Total
Domestic
(Single-Country)
33
12
81
77
14
220
Multinational
16
198
221
Total
49
12
279
78
18
441
* Source : KFDA, 2012
Korea has continuously worked on the development of stem cell

therapy to lead the future medicines such as talor-made
preventive medicines, and as a result succeeded in developing
stem cell therapy products and stepping out into world markets.
Currently, 3 products from domestic companies are on the market. In addition,
25 clinical trials are underway.
In July 2011, PARMICELL s Hearticellgram-AMI was licensed as the world s first
stem cell therapy product.
MEDIPOST s self-developed Cartistem went through phase-I and II-a clinical trials
approved by US FDA and has been exposed in November 2012, which was the first
time in the history of domestic pharmaceutical companies.
Emerging of Successful
Biotech Companies
Biotech companies in Korea have have invested in research and
development over 10 years since their foundation, and now they are
expanding their capability into commercialization.
As biotech companies like CELLTRION have achieved commercial successes,
bioindustry in Korea is expected to take a leap forward.
Biotech companies such as CELLTRION, MEDYTOX, MEDIPOST, SEEGENE, BIONEER and
TOOLGEN have successfully established in Korean market, based on their own know-hows and
platform technologies. Now they are more likely to enter the global market.
CELLTRION has core technologies to develop antibodies and to combine therapeutic antibodies and synthetic
drugs. MEDYTOX succeeded in turning botulinum toxin into cosmetic and therapeutic products and has the
technologies to preserve and transplant stem cells and cord blood.
Only 7 biotech companies were listed in the Korean stock market (KOSDAQ) before the
year 2000, but since then, more than 50 companies have listed on it, showing that their
strong growth.
In 2012, 57 biotech companies were listed in KOSDAQ. As of March 2013, there are 13
companies having one-trillion-won market value in KOSDAQ, compared to only 4 companies as
of March, 2012. 2 of them are biotech companies.
Ranking Company
Company
Products
Cell Types
Autologous bone marrowFCB

Hearticellgram
derived mesenchymal
PHARMICELL -AMI
stem cells
MEDIPOST
CARTISTEM
ANTEROGEN CUPISTEM
Umbilical cord bloodderived mesenchymal

stem cells
Target Diseases
Improvement of LVEF
in acute myocardial
infraction patients
Treatment of knee
cartilage defects
Autologous adipose-derived Treatment of Crohn s

fistula
mesenchymal stem cells
Date of
Approval
2011.7.1
2012.1.18
2012.1.18
Total Market Value
Ranking Company
Total Market Value
CELLTRION
4.6933-trillion won
DAUM
1.2616-trillion won
PARADISE
1.9098-trillion won
GS Home Shopping
1.2410-trillion won
CJ O Shopping
1.9014-trillion won
10
POSCO ICT
1.0963-trillion won
Seoul Semiconductor
1.7987-trillion won
11
SFA
1.0539-trillion won
CJ E&M
1.4150-trillion won
12
SEEGENE
1.0357-trillion won
SK Broadband
1.3614-trillion won
13
PARTRON
1.0097-trillion won
DONGSUH
1.3078-trillion won
* Source : Korea Technology Transfer Center (as of Mar. 8, 2013)
35
Governmental Strong
Promotion Policy
Biofund to Nurture Bioindustry

In 2011, Seoul City and the Ministry of Trade, Industry and Energy created a 75 billion won fund
titled Korea Seoul Life Science Fund through a public-private joint investment. It invests more
than 60% of the entire fund in midium-sized companies with sales revenue of more than 30 billion
won or unlisted small or medium ventures in the biologics or medical equipment industries.
Beneficiaries of Korea Seoul Life Science Fund : Kang Stem Holdings, EARLOGIC Korea, Crystal Genomics,
PCL, Pathway Genomics, PHARMABCINE and CORESTEM
The Korean government selected Bioindustry as a new

economic growth engine, and has improved systems and
promotion policies (Bio-Vision 2016). The government is focusing
on the efficient management of national R&D programs,
supporting systems for bioindustry, establishment of cutting-edge
medical clusters and training of experts.
Investment of total R&D in biotechnology sectors in Korea is continuously
growing
As mentioned above, the biotechnology sector comprised 19% (2.5808-trillion won) of
the national R&D budget in 2012.
Direction of R&D investment in biotechnology

According to a report titled Investment Direction of the 2014 Government R&D
Investment, released by the National Science and Technology Commission, the
government has the plan to expand investment in R&D related to innovative
technologies for people s wealthy and happy life, safety and security, and future megatrends & needs. R&D for improving industrial structure is also one of strategic area of
governmental investments.
To cope with chronic diseases and social/economic issues caused by urbanization and aging,
investment will be made in public welfare enough to make people feel wealthier and happier.
Biotechnology can make the
With infrastructure for ICT, the way will be paved for advancement of researches on life science
and healthcare.
Strong investment will be made for platform technologies of biotechnology and healthcare
industry to make them as a economic growth engine for global market.
Supporting Policy for Pharmaceutical Industry
impossible possible and it is

a new hope for the future
The Ministry of Health and Welfare will streamline the pricing system and the approval
procedures for new medical technology and medicine, expand government R&D
supports, improve R&D support system, increase tax incentives and develop new
financing method for R&D related to exports.
37
BioClusters
in Korea
1. Daegu-Gyeongbuk High-Tech Medical Cluster
Major Bio-Clusters
Korea makes a hi-tech medical complex, in line with the huge-scale national project to
develop medical industry as a national strategic industry. It will be a global hub of
medical industry to develop it as a next-generation economic growth engine. They will be
constructed in Daegu and Osong, respectively, and these constructions are scheduled to
be completed by 2013.
The Korean government has been forstering the Bio-cluster

System and creating specialized hubs and R&D complexes in
each district with the aim of strengthening its competitiveness in
biotechnology, which is expected to enable the setup of interregional human, technical and industrial networks, local
innovation and the balanced development of biotech industries.
A total of 25 bio-clusters (9 Bio Venture Centers and 16 Regional Technology
Innovation Centers) have been formed in 15 cities or provinces in Korea. They
support 3 specialized hubs, biomedicine, marine biotechnology and life care
material. Korea Bio-Hub Center, founded in 2004, takes the initiative in
networking with bio-clusters and activating academic-industrial joint
researches.
Daegu-Gyeongbuk Hi-Tech Medical Cluster, planned to be created in Daegu, will be 1.03

square kilometers in area, in which a total of 4.6-trillion won will be invested. The
construction is underway.
The complex is composed of 4 core research centers including, new drug development center,
medical device development center, laboratory animal center, and clinical drug manufacturing
center, and will translate basic research into clinical trial stages to develop first-in-class
(innovative) new drugs and medical devices.
The cluster will focus on synthetic chemical drugs and IT-based high-tech medical
devices, unlike the Osong complex, in order to differentiate them from others. It is
enabled by 12 hospitals equipped with outstanding clinical trial infrastructure and by the
synchrotron radiation (Pohang).
For more information, refer to the website of Korea Bio-Hub Center (www.koreabiohub.org)
Koreas Bio-Clusters are established in major cities and are all connected,
forming one national cluster within one hours distance by air
Cluster
Value chain
Daegu Hi-Tech Medical

Cluster (Medivalley)
Pharma / BT/ Medical device

R&D /Production
Osong BioValley
Bio-Pharma/Medical device
R&D
Innopolis Daedeok
Bio-Pharma
Wonju Medical device

Cluster
Medical device
R&D / Production
BT, Pharma / Healthcare
R&D / Production
Bio-Healthcare
R&D / Production
Healthcare
R&D /Leisure
Gyeonggi-do
Techno valley
IFEZ
Bio-Complex
Jeju Healthcare Town
R&D
* Source : Daegu-Gyeongbuk Medical Innovation Foundation (http://www.medivalley.re.kr)
* Source : Invest Korea (http://www.investkorea.org/)
Bio-Clusters in Korea
41
2. Osong BioValley
3. Innopolis Daedeok
Osong (North Chungcheong Province) has Osong BioValley equipped with

world-class biotech R&D infrastructure to make Korea the hub of the integrated
biotech industry. Osong BioValley provides world-class medical R&D
innovation, medical services, bio-tourism, culture and education, in which
Osong Life Science Complex and Medical Innovation Cluster were created
in 2008 and 2009 respectively. It has been occupied by a variety of biotech
companies since six government-run healthcare agencies moved to there in
2010, and now it is emerging as the center of Korean biotechnology.
The Innopolis Daedeok (yuseong-gu and daedeok-gu of daejeon metropolitan city)

refers to Daedeok Research Complex , Daedeok Techno Valley and Daejeon
Industrial Complex. It is the Korea s biggest R&D complex having an area of 67.8
square kilometers.
The complex is 9,545 square kilometer in area. It is equipped with biomedical

facilities and composed of Life Science Complex-1 , Medical Innovation
Cluster , Life Science Complex-2 and Public Health Administration Town .
In particular, it has the merits of being adjacent to KTX Osong Station.
Functionally, it supports not only R&D for new drugs or a medical devices but
the commercialization of them, in addition to administrative affairs.
Considering that the complex has 6 government-run healthcare institutions
including KFDA and is adjacent to Daedeok R&D Complex having many
research institutes including Korea Research Institute of Bioscience and
Biotechnology (KRIBB), it specializes in biotherapeutics and BT-based hightech medical devices.
Recently, an agreement with Germany s Berlin-Brandenburg Center for Regenerative
Therapies (BCRT) was made for foundation of a research institute for stem cell and
regenerative medicine (May 2012).
The master plan of the Innopolis Daedeok was established in 1973 to advance basic and
special sciences, and research institutions began to go up in the site from 1978. As of
2011, the complex has been occupied by about 60,000 workers at 30 government-run
agencies, 11 public institutions, 14 national institutions, 30 non-profit institutions,
5 universities and 1,306 companies (1,399 in all).
Strengths of Innopolis Daedeok
In Innopolis Daedeok, there are many government-funded institutes related to innovative
industries such as biotechnology, information technology, nanotechnology, robotic and aerospace.
Its R&D capability is highest in Korea, and its workers are equivalent to 10% of those having
doctoral degrees in sciences and engineering in Korea. The KAIST, called Korean MIT ,
produces world-class scientists and researchers, and the complex functions as a reservoir of
professional human resources necessary for industries and technical development in Korea.
The Innopolis, based on integrated research techniques, is advantageous to technology-intensive
companies and startups. Its occupants, Korea s best ventures and other various companies, are in
possession of commercialized technologies such as DRAM and SRAM chips, LCD modules, cell
phone technologies and wireless wide area network technologies.
* Source : INNOPOLIS Foundation (http://ddi.or.kr)
43
4. Wonju Medical Device cluster
5. Gyeonggi-do Techno Valley
Wonju Medical Equipment Techno Valley development project has been

pushing ahead for bringing Wonju as a city of global medical equipment
industry since 1998. It was founded for supporting the industries, specialized in
medical equipment, for vitalization of regional economy and improving
international competitiveness of domestic medical equipment industry by
supporting things such as training man power and technology cooperation,
establishment support, production function and marketing through organic
cooperation with industry, university and institute.
Gyeonggi Province in Korea has been leading technical innovation together with Seoul
and Incheon. Being easy to recruit highly skilled workers in virtue of geographical
proximity to the capital city of Seoul, it maintains active partnership with the Institute
Pasteur Korea and other large global clinical trial centers. It is also adjacent to foreigninvested companies, such as GE Healthcare and Siemens, and large local pharmaceutical
corporations. Pangyo Techno Valley and Gwanggyo Techno Valley, conducting R&D
activities regarding the convergence among BT, IT and NT, underlie the infrastructure.
With a close academic-industrial cooperation, it boosts the medical equipment

industry and invigorates local economy by backing up researches,
developments, technologies, product licensing, test product making, domestic
and overseas marketing, preclinical and clinical trials and startups. In addition,
it provides research facilities, leases flatted factory buildings, and sells factory
sites in lots.
It is largely composed of Medical Industry Techno Tower, Venture Center, Wonju
Medical Technology Techno-park and Donghwa Medical Instrument Complex, and has
been tenanted by more than 90 companies.
Technical Support Center, located there, has been designated as the first Underwriter
Laboratories Witness Test Data Program (UL-WTDP) in Korea in March 2013, and it
has been possible for medical device exporters to get safety certificates from the cencer.
The Pangyo Techno Valley (Pangyo, Seongam City) is a hi-tech innovation cluster having
an area of 661,925 square meters. It aims to establish a specialized global cluster covering
reseaech (R), information (T), and trade (T) for IT and other IT R&D-related convergence
technologies and implement a ubiquitous trial model.
At present, it has 41 companies in addition to R&D Center, Indusy-Academia Research institute
R&D Center and Public Support Center and offers optimal business environment. It is expected
to be an important foothold for the hi-tech industry in gyeonggi province, together with
gwanggyo, ansan and gwacheon.
* Source : Pangyo techno valley (http://www.pangyotechnovalley.org/)
str
W
on
yT
ec h n o Valley
Gwanggyo Techno Valley (Gwanggyo, Suwaon) is a hi-tech R&D complex having an

area of about 11.3 square kilometers. It is based on hi-tech industries such as BT, IT and
NT. It was created for the purpose of reviving local economy, cultivating outstanding
human resources and strengthening national competitiveness.
ju M
du
e di c a l I n
Five facilities, including Gyeonggi Bio Center, Gyeonggi R&DB Center and Advanced Institutes
of Convergence Technology, underlie its R&D infrastructure. Gyeonggi Bio Center, specializing
in the promotion of pharmaceutical and biotech industries, provides occupants with the most
advanced laboratory devices.
* Source : Gwanggyo Techno Valley (http://www.ggtv.or.kr/)
* Source: Wonju Medical Industry Techno Valley (http://www.wmit.or.kr/)
45
6. Incheon Free Economic Zone (IFEZ) Bio-Complex
7. JDC, Jeju Healthcare Town
The Korean government appointed Incheon Free Economic Zone (IFEZ) as a

forward base for global business and has guaranteed to actively support its
economic activities. The site of 169.5Km2, including Incheon International
Airport, Incheon Harbor, Songdo, Yeongjong and Cheongna International City,
was appointed as the Korea s first economic free zone in August 2003.
Recently, the construction of Jeju Healthcare Town has begun for the purpose of
inviting local and foreign companies and creating a global medical environment to
vitalize medical business. It is expected to enable visitors not only to take recreation but
to get medical services in Jeju Island famous for picturesqueness. It is planned to be
created in a site of about 1.5 square kilometers with an investment of 784.5-billion won.
The site began to be renovated in 2011, and the town is scheduled to be opened in 2015.
IFEZ is suitable for business, logistics, advanced industry, biomedical,

education and tourist & culture. In the case of the biomedical industry, a
customized and regenerative medicine complex was created for the purpose of
being ranked 3rd in the world for technological strength.
The biomedical industry is boosted with the creation of a Medi Park and a medical
city Yeongjong Medi City , the attraction of foreign hospitals and the development of
International BIT-Port .
IEFZ has been occupied by CELLTRION, Samsung Bio Logics, I-SENS (a glucometer
producer), KD Corporation (a silica gel manufacturer), BINEX and BERNA Biotech
Korea, and a large foreign hospital is scheduled to be founded there.
Jeju Healthcare Town will be largely composed of Wellness Park, Medical Park and R&D
Park.
Wellness Park will be a medical and recreational complex, in which a condominium, a water park
and Wellness Mall will go up.
Medical Park will be a medical complex to provide the most advanced medical services, which
will be equipped with hospitals, specializing in plastic surgery, dentistry and cancer treatment, and
recreational facilities for the elderly and retirees.
R&D Park is to research biotechnology and medicine, in which Medical R&D Center , AntiAging
Center and Rehabilitation Center will be founded.
Present State
Enterprise Project
Enterprise Outline
Target Investment Industry
Construction of
Songdo
Biomedipark
Enterprise period
2010. 1 ~ 2014. 12(1st Phase)
2015. 1 ~ 2020. 12(2nd Phase)
Biomedical production /
manufacturing facilities and
research centers
Construction of
Bio-Research Complex
Enterprise period
2009. 1 ~ 2013. 12
Primary facilities
Yeongu-dong, Imsang-dong,
apartment factories, business
facilities, administrative buildings
Enterprises closely involved in

bio-industries and BT, NT, and
IT research
Construction of
Yeongjong Medicity
Enterprise period
2009. 1 ~ 2015
National and international
treatment and pharmaceutical
Primary facilities
International hospital, schools, research development organizations
centers, residences, service facilities
Construction of
Cheongna International
BIT-Port
Enterprise period
2006. 9 ~ 2014. 12
Primary facilities
Education and management facilities,
research facilities, academic-industrial
cooperation facilities
Songdo International
Hospital
Enterprise period
2005. ~ 2013
In October 2012, China s Greenland Group signed an investment contract of 1-trillion won.
Currently, the phase-I construction is underway.
In February 2013, a Korea-China consortium was formed and two companies (SEOWOO in Korea
and ZHONGDA DICHAN in China) singed a MOU.
BIT-related fused technology

education, research, and
industrialization facilities
Managing organizations
Johns Hopkins Hospital and
Seoul University Hospital
* Source : JEJU Free International City Development Center (http://www.jdcenter.com)
* Source : Incheon Free Economic Zone (http://www.ifez.go.kr)
47
BiotechLeading
Entities in
Korea
Status of Biotech & Healthcare

Business of Large-sized Companies
Company
Major issues
- LG Life Science promotes bio business, invests in biosimilar
- Approved growth hormone Valtropin (generic) licensed by U.S. FDA and EMEA
- Enbrel s biosimilar, clinical trial in progress
- Construction of a biosimilar plant in the Osong high-tech Medical Complex is underway
- Concludes a contract with Mochida(Japan) for the joint development and sale of biosimilars
(Nov. 2011)
- Develops Korea s 19th new drug, Zemiglo (anti-diabetic) (2012)
An industrial ecosystem has been formed by active participations

of the large-sized companies in Korea, expecting biotech and
healthcare sectors to be the key to the next growth industry.
- Conducts a demonstration project Smart Care Service (ubiquitous healthcare service)

jointly with Daegu City (LG Electronics) (2010)
As the aging population is quickly increasing throughout the world, especially

in Korea, leading electronic, chemical and telecommunications companies in
Korea have been making inroads into biotech and healthcare markets in recent 3
or 4 years.
- Founds a new department to carry out ubiquitous healthcare business (SK Telecom) ;
acquires shares in NanoEnTek , an in vitro diagnostic (IVD) unit manufacturer ; carries
out healthcare business with a venture, Healthcare Connect , founded jointly with Seoul
National University Hospital in January 2012 ; enters the healthcare market in China by
acquiring a 49 percent stake in Tian Long , a diagnostic unit manufacturer in China
In particular, the fact that Samsung going into the biotech business makes the biotech
industry in Korea highly anticipated. Its subsidiaries, Biologics and Bioepis, went into
the biosimilar business, and moreover Samsung Electronics has gotten stuck into the
medical device industry.
- Regards sunlight, biofuels and secondary batteries as the future green energy, and plans an
investment of 4.5-trillion won until 2020 (SK Energy)
Company
- Founds SK Biopharmaceuticals a subsidiary to specialize in new drug development as

part of the healthcare business (Apr. 2011)
- Focuses on the development of vaccines, biomedicines and botanical drugs, and conducts
the Korea s first phase I clinical trial on a cell culture influenza vaccine (SK Chemical)
(Sep. 2012)
Major issues
- Selected as a future growth engine business such as bio and solar energy (2009)
- Selected the Bio-Health area as a new business (2010)
- KFDA approval for HD203, an Enbrel s biosimilar (Sep. 2012)
- Established a joint venture with Quintiles (USA) for a bio similar business
(2011)
- Biosimilar plant construction plan in Osong BioValley

- Focuses on the medicine, anti-obesity drug and aesthetic businesses (Dream Pharma)
- Takeover of the medical instrument company Medison (2011)

Develops medical devices such as blood analyzers, digital x-ray units and
others
Conducts M&A activities to win domestic and overseas medical device
companies such as GES, NEXUS, NEUROLOGICA, etc
- Launches Samsung Biologics, a joint biomedicine company (Apr. 2011)
- Launches Biogen Idec and a joint company Samsung Bioepis to develop and
commercialize biosimilars (Feb. 2012)
- Sets up the bioinformatic business (Samsung SDS) and began to provide gene
analysis services (SamsungGenome.com) from 2011
- Starts the bioindustry with biochemical and biofuel sectors (Samsung
Petrochemical) (2011)
- Selects biotech and pharmaceutical sectors as new promising businesses, and promotes them.
Lays foundation for the pharmaceutical industry, taking over Youngjin Pharm, and takes
over Mazence, a biotech venture specializing in new drug development (2012)
- Founds a subsidiary, KT&G Life Science, and focuses on the development of new drugs
(Mar. 2012)
- Founds a medical-ICT convergence company Who Health Care jointly with Severance
Hospital (Jul. 2012)
Builds up a smart medical ecosystem , developing and providing a hospital information
system
- Starts the biotech industry, founding a biotech venture in USA (2002)
- Begins to develop a next-generation medical robot jointly with Asan Medical

Center (Mar. 2012)
Invests its own found into the development of stem cell therapy products, a new
promising business (Sep. 2011)
Biotech Leading Entities in Korea
51
Biotech Companies
Companies
(as of October 2012)
Biotech Companies Listed on KOSPI (7)

Companies
Fields
Websites
LG Life Sciences
Biopharmaceutical
www.lgls.co.kr
SK Chemicals
Biopharmaceutical
www.skchemicals.com
VGX International
Biopharmaceutical
www.vgxi.com
SEWON CELLONTECH
Biopharmaceutical
www.sewoncellontech.com
RNL BIO
Biopharmaceutical
www.rnl.co.kr
Orient Bio
Biopharmaceutical
www.orient.co.kr
CKDBIO
Biopharmaceutical
www.ckdbio.com
Biotech Companies Listed on KOSDAQ (50)
Fields
Websites
Bioland
Biochemical
www.biolandkorea.com
Biotoxtech
Bioassay
www.biotoxtech.com
Sansung L&S
Biochemical
www.sansung.co.kr
Seoulin Bioscience
Bio-equipment
www.seoulin.co.kr
Celltrion
Biopharmaceutical
www.celltrion.com
Suprema
Bio-equipment
www.suprema.co.kr
Skynewpharm
Biopharmaceutical
www.skynewpharm.com
Cellbiotech
Biofood
www.cellbiotech.com
Seegene
Biopharmaceutical
www.seegene.co.kr
CTCBIO
Agriculture
www.ctcbio.com
Estech Pharma
Biopharmaceutical
www.estechpharma.com
Oscotech
Biopharmaceutical
www.oscotech.com
EagleVet
Agriculture
www.eaglevet.com
InnoCell
Biopharmaceutical
www.greencrosscell.com
ISUAbxis
Biopharmaceutical
www.abxis.com
Easy Bio System
Biofood
www.easybio.co.kr
Equis & Zaroo
Biopharmaceutical
www.equispharm.com
Infopia
Bio-equipment
www.infopia21.com
Ilshin Lab.
Bioprocess and equipment
www.1sbb.com
Genexine
Biopharmaceutical
www.genexine.com
Genic
Bio-cosmetic
www.genic21.com
Cheil Bio
Agriculture
www.cheilbio.com
CAVAC
Biopharmaceutical
www.cavac.co.kr
Companies
Fields
Websites
JW-Shinyak
Biopharmaceutical
www.jw-shinayk.co.kr
NeoPharm
Biopharmaceutical
www.neopharm.co.kr
Gene Matrix
Biopharmaceutical
www.genematrix.net
Neurotech
Biopharmaceutical
www.neurotech.co.kr
Gene Biotech
Biopharmaceutical
www.genebiotech.co.kr
Deasung Microbiological Labs.
Biopharmaceutical
www.dsmbio.com
Cha Bio & Diostech
Biopharmaceutical
www.chabio.co.kr
Daehan New Pharm
Biopharmaceutical
www.dhnp.co.kr
K-Mac
www.kmac.com
Lifecord
Biopharmaceutical
www.lifecord.co.kr
Komi Pharm
Biopharmaceutical
www.komipharm.com
Rexgene Biotech
Biofood
www.rexgenebio.co.kr
KOLON Life Science
Biopharmaceutical
www.kolons.co.kr
Macrogen
Bioassay
www.macrogen.co.kr
Crystal Genomix
Biopharmaceutical
www.crystalgenomix.com
Medytox
Biopharmaceutical
www.medytox.com
PharmswellBio
Bio-equipment
www.pharmswell.com
Medipost
Biopharmaceutical
www.medi-post.co.kr
Kolmar Korea
Biopharmaceutical
www.kolmar.co.kr
Medifron
Biopharmaceutical
www.medifron.com
Hans Biomed
www.hansbiomed.com
Binex
Biopharmaceutical
www.bi-nex.com
Hwail Pharmaceutical
Biopharmaceutical
www.hwail.com
ViroMed
Biopharmaceutical
www.viromed.co.kr
Dong-A Pharmtech
Biopharmaceutical
www.dapt.co.kr
Bioneer
Bio-equipment
www.bioneer.co.kr
DNA Link
Bioassay
www.dnalink.com
* Source: The Korea Biotechnology Industry Organization
53
Research Institutes
Korea Research Institute of Bioscience and Biotechnology (KRIBB)
National Cancer Center (NCC)
Founded in 1985, KRIBB conducts fundamental research on the origins of life phenomena as
well as cutting edge biotechnology research about new drug discovery, novel bio-materials,
development of bio-energy sources, and expansion of food production.
Founded in 2000, the NCC has persevered to lessen the burden of cancer for Koreans by
conducting and offering assistance to cancer research, diagnosing and treating cancer patients,
assisting in the National Cancer Control Initiatives, and finally, educating and training cancer
specialists.
Mission
To carry out R&D and related projects in the field on bioscience and
biotechnology in joint effort with other research institutes, academic, and
businesses at home and abroad
Mission
To disseminate the results of its scientific research and technological development
The NCC strives to improve national health and welfare by reducing the
incidence and mortality of cancer through research, patient care, education &
training, and support for the national cancer control programs.
For more information, please visit the website - www.kribb.re.kr
For more information, please visit the website - www.ncc.re.kr
Korea Research Institute of Chemical Technology (KRICT)
Korea Food Research Institute (KFRI)
Established in 1976, the KRICT has fueled the growth of Korea s chemical industry. The
institute recently selected 4 key research areas for concentrated investment: the development of
eco-friendly chemical process technology and high value-added green chemical materials, the
acquisition of new substance pipelines for disease treatment, and the development of green
convergence chemical technology to act as future growth engines.
Korea Food Research Institute, the cradle of Korea s food science and technology, is a governmentfunded entity established in 1988 so as to contribute to the development of food, agriculture, forestry
and fisheries industries and to the improvement in the quality life of the people by means of
developing, diffusing and intensifying fundamental technologies in the field of food science.
Mission
KRICT seeks to improve the competitiveness of the chemical industry and promote the establishment of
new national scale industries by developing and disseminating original chemical technologies and relevant
convergence technologies; and by managing the public chemical technology infrastructure.
Conducting researches on longevity science, functional foods, safe distribution

and food processing technology to improve the health of the people and the
quality of their life; spreading the research achievements; providing
technological support
For more information, please visit the website - www.krict.re.kr
For more information, please visit the website - www.kfri.re.kr
Korea Institute of Oriental Medicine (KIOM)
International Vaccine Institute (IVI)
KIOM is the only government-funded research institute for traditional Korean medicine. Since
its establishment in 1994, KIOM has strived to develop future-oriented original technology for
Korean medical treatments, develop core technology of Korean medicine-based herbal drugs to
support the National Agenda, and establish Korean medical knowledge and the informatics
infrastructure based on medical knowledge accumulated over centuries. Through these efforts,
the institute is taking the lead in scientific advancement, standardization, industrialization and
globalization of Korean medicine.
The International Vaccine Institute (IVI) is an international nonprofit organization that was
founded on the belief that the health of children in developing countries can be dramatically
improved by the use of new and improved vaccines.
Mission
Mission
The mission of KIOM is to creatively develop Korean medicine, building its new
values and contributing to healthy life.
For more information, please visit the website - www.kiom.re.kr
Mission
IVI is hosted by the Republic of Korea and is headquartered in the countrys capital city, Seoul. The
Institutes state-of-the-art facility was built with the generous support of the Korean government and
houses Biosafety Level 3+ (BSL3+) laboratories, which allow vaccine research on dangerous
pathogens such as those that cause avian influenza and tuberculosis.
Discover, develop, and deliver safe, effective and affordable vaccines
for the worlds developing nations
For more information, please visit the website - www.ivi.int
55
Organizations &
Associations
Korea
Biotechnology
Industry
Organization
(KOREA BIo)
Founded in 2008, As the organization representing the biotechnology industry as per Article 38
of the Industry Development Act of the Korean Ministry of Trade, Industry and Energy, the
Korea Biotechnology Industry Organization strives to enhance links between the many
businesses that constitute the biotechnology industry and while acting as a catalyst for further
technological development and industrialization
For more information, visit http://www.koreabio.org
Korea Drug
Research
Association
(KDRA)
Founded by law in 1986 as a non profit organization, the KDRA represents Korea s
R&D-oriented, innovative companies. The major purpose of establishment is to promote
pharmaceutical research & development activities especially through promoting activation of
research & development activities and raising the efficiency of R&D activities by furthering
joint projects between industrial, academic and research fields
For more information, visit http://www.kdra.or.kr
Korea
Pharmaceutical
Manufacturers
Association
(KPMA)
KPMA, since its foundation in 1945, along with pharmaceutical companies has been
committed to improve healthcare for all mankind and develop pharmaceutical industry. KPMA
aims to strengthen collaboration of Korean companies with pharmaceutical companies already
having experience in product launches in the overseas markets
Clinical Trial Centers (CTC) and

Contract Research Organization (CRO)
Clinical Trial Centers (CTC)
No
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
Company
Websites
Clinical Trials Center, Seoul National University Hospital

Clinical Trials Center, Inje University Pusan Paik Hospital
Clinical Trials Center, Kyungpook National University Hospital
Clinical Trials Center, Ajou University Medical Center
Clinical Trials Center, Yonsei University Health System
Clinical Trials Center, Chonnam National University Hospital
Clinical Research Coordinating Center,
Catholic Medical Center of the Catholic University of Korea
Clinical Research Center, Asan Medical Center
Clinical Trials Center, Chonbuk National University Hospital
Clinical Trials Center, Samsung Medical Center
Clinical Trials Center, Inha University Hospital
Clinical Trials Center, Chungnam National University Hospital
Clinical Trials Center, Korea University Anam Hospital
Clinical Researchi Center, Dong-A University Hospital
Clinical Trials Center, Pusan National University Hospital
http://ctc.bri.snuh.org
http://www.paikctc.ac.kr
http://ctc.knu.ac.kr
http://rctc.ajoumc.or.kr
http://sev.iseverance.com/ctc
http://www.cnuhctc.com
http://cmccrcc.catholic.ac.kr
http://crc.amc.seoul.kr
https://www.jbctc.co.kr
http://ctc.samsunghospital.com
http://www.inha.com
http://www.cnuh.co.kr
http://ctc.kumc.or.kr
http://ctc.damc.or.kr
http://www.pnuhmri.org
For more information, visit http://www.kpma.or.kr
Contract Research Organization (CRO)

Korea National
Enterprise for
Clinical Trials
(KoNECT)
KoNECT was established in December 2007 with wholehearted support from the Korean
government, academics and related business industries in order to meet the increasing demands
for clinical trials and to raise national competitiveness by fostering necessary human resources,
developing core technology, and building a solid infrastructure to become a global clinical trial
hub
For more information, visit http://www.konect.or.kr
Korea Health
Industry
Development
Institute
(KHIDI)
Korea Biomedicine
Industry
Association
(KoBIA)
Korea Health Industry Development Institute (KHIDI) is a public organization that consists of
a group of experts dealing with various programs on promoting and developing health industry
in Korea, while helping improve the national healthcare services
For more information, visit http://www.khidi.or.kr
Established for conducting to the global competitiveness of Korean biomedicine industry and
for this propose we make the utmost effort to improve the authorization policy of biomedicine.
we seek to arrange timely distribution of industry news and our training programs of high-level
biomedicines for this propose as well
For more information, visit http://www.kobia.kr
No
Company
Websites
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
Global Health Care

DreamCIS
MedicalExcellence
Apple Tree laboratory
Synex
Seoul CRO
Seoul Clinical laboratory (SCL)
Seoul Pharma laboratory (SPL)
Sejong CRO
Solomon Medical Research
C&R Research
ACROVAN
ADM Korea
LSK Global PS
GDFI
Pharma CRO
Korea Medicine Research Institute (KMRI)
http://globalhealthcare.co.kr
http://www.dreamcis.com
http://www.mediex.co.kr
http://www.applelab.co.kr
http://www.synex.co.kr
http://www.seoulcro.co.kr
http://www.scllab.co.kr
http://www.splab.co.kr
http://www.sjcro.com
http://www.solomonmed.com
http://www.cnrres.com
http://www.acrovan.com
http://www.admkorea.co.kr
http://www.lskglobal.com
http://www.gdfi.co.kr
http://www.pharmacro.co.kr
http://www.kmri.co.kr
Competitiveness
Biotechof
Leading
Korea in
Entities
Biotechnology
in Korea
57
T h i n k
t o m o r ro w
f
e a r t h
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