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    Pharmacology MCQ

    Uploaded by

    Nack Tie
    This document contains 51 multiple choice questions about various pharmacological topics such as: - Components of cocktail therapy for AIDS (question 1) - Pharmacological mechanisms and effects of various drugs like atropine, cardiac glycosides, glucocorticoids, etc. - Pathogens susceptible to different antibiotics - Side effects and uses of drugs like streptomycin, oxytocin, heparin, etc. The questions cover a wide range of pharmacology topics testing knowledge of drug mechanisms, effects, uses, side effects and more.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Pharmacology MCQ

    Uploaded by

    Nack Tie
    505 views36 pages
    This document contains 51 multiple choice questions about various pharmacological topics such as: - Components of cocktail therapy for AIDS (question 1) - Pharmacological mechanisms and effects of various drugs like atropine, cardiac glycosides, glucocorticoids, etc. - Pathogens susceptible to different antibiotics - Side effects and uses of drugs like streptomycin, oxytocin, heparin, etc. The questions cover a wide range of pharmacology topics testing knowledge of drug mechanisms, effects, uses, side effects and more.

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    MCQ

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    This document contains 51 multiple choice questions about various pharmacological topics such as: - Components of cocktail therapy for AIDS (question 1) - Pharmacological mechanisms and effects of various drugs like atropine, cardiac glycosides, glucocorticoids, etc. - Pathogens susceptible to different antibiotics - Side effects and uses of drugs like streptomycin, oxytocin, heparin, etc. The questions cover a wide range of pharmacology topics testing knowledge of drug mechanisms, effects, uses, side effects and more.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    505 views36 pages

    Pharmacology MCQ

    Uploaded by

    Nack Tie
    This document contains 51 multiple choice questions about various pharmacological topics such as: - Components of cocktail therapy for AIDS (question 1) - Pharmacological mechanisms and effects of various drugs like atropine, cardiac glycosides, glucocorticoids, etc. - Pathogens susceptible to different antibiotics - Side effects and uses of drugs like streptomycin, oxytocin, heparin, etc. The questions cover a wide range of pharmacology topics testing knowledge of drug mechanisms, effects, uses, side effects and more.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 36

    Question 1

    1.

    Which is a component of cocktail therapy vs.


    AIDS?
    Answer
    Amantadine
    Zidovudine
    Acyclovir
    Vancomycin
    Ribavirin (virozole)

    1 points

    Question 2
    1.

    Atropine can induce


    Answer
    "tachycardia, dry mouth"
    "bradycardia, miosis"
    "tachycardia, salivation"
    "tachycardia, miosis"

    "bradycardia, salivation"

    1 points

    Question 3
    1.

    Lugols Solution (Iodine) can be used to


    treat
    Answer
    hyperthyroidism
    hypogonadism
    allergy
    diabetes
    hypothyroidism

    1 points

    Question 4
    1.

    After long-term use of Glucocorticoids,


    rebound phenomenon will occur if the dosage
    is reduced rapidly, it is because
    Answer

    adrenal suppression
    iatrogenic Cushing syndrome
    glucocorticoid dependence
    increased ACTH secretion
    decreased pituitary function

    1 points

    Question 5
    1.

    Which drug is addictive antitussive


    Answer
    Ammonium chloride
    Dextromethorphan
    Benzonatate
    Codeine
    Pentoxyverine

    1 points

    Question 6
    1.

    Pharmacological mechanism of Cardiac


    Glycosides is
    Answer
    Inhibition of cAMP
    Inhibition of H+-K+-ATPase
    Inhibition of Na+-K+-ATPase
    Inhibition of P-450
    Inhibition of Phosphodiesterase

    1 points

    Question 7
    1.

    Which drug can be used for abortion


    Answer
    Prostaglandins
    Ritodrine
    Ergometrine
    Oxytocin
    Indomethacin

    1 points

    Question 8
    1.

    Which of the following drugs can inhibit the


    DNA-dependent RNA polymerase?
    Answer
    Penicillin G
    Rifampin
    Streptomycin
    Chloramphenicol
    Cefoperazone

    1 points

    Question 9
    1.

    The effect of Cholestyramine on blood lipid


    is
    Answer
    Reduce TC and LDL-C
    Reduce TG and HDL
    Reduce CE and FFA

    Reduce TC and VLDL


    Reduce TC and CM

    1 points

    Question 10
    1.

    Which one is NOT a main adverse effect of


    Streptomycin?
    Answer
    Nephrotoxocity
    Vestibular toxicity
    Hepatotoxicity
    Neuromuscular Paralysis
    Cochlear toxicity

    1 points

    Question 11
    1.

    The most active aminoglycoside against


    Mycobacterium tuberculosis is
    Answer

    Kanamycin
    Neomycin
    Amikacin
    Streptomycin
    Tobramycin

    1 points

    Question 12
    1.

    The H2 receptor antagonists are mainly used


    to
    Answer
    hypertension
    asthma
    diabetes
    intestinal spama
    peptic ulcer

    1 points

    Question 13
    1.

    Which pathogen is susceptible to


    Azithromycin?
    Answer
    Plasmodium
    G coccus
    G bacillus
    Rickettsia
    Anaerobic bacteria

    1 points

    Question 14
    1.

    The most important mechanism of


    Cephalosporins acquired resistance is
    Answer
    the change of metabolism pathway
    produce the -lactamases
    reduction of cell membranes perrmeability
    active efflux system
    modification of target sites

    1 points

    Question 15
    1.

    Which drug has the mucoprotective effect for


    ulcer treatment
    Answer
    Ranitidine
    Magnesium trisilicate
    Omeprazole
    Atropine
    Sucralfate

    1 points

    Question 16
    1.

    The correct time for alternate-day


    adiministration of Glucocorticoids is
    Answer
    4:00 AM
    8:00AM

    8:00 PM
    4:00 PM
    12:00 AM

    1 points

    Question 17
    1.

    The common effect of Nitroglycerin and


    Propranolol in angina treatment is
    Answer
    decrease heart rate
    decrease peripheral resistance
    decrease myocardiac contraction
    decrease myocardiac oxygen consumption
    decrease ventricular volume

    1 points

    Question 18
    1.

    Which of the following effect is the adverse


    drug effect of Heparin

    Answer
    Peptic ulcer
    Pypertension
    Asthma
    Bleeding
    Abnormalities of renal function

    1 points

    Question 19
    1.

    Which of the following antibacterial agents


    can inhibit folic acid metabolism?
    Answer
    Quinolones
    Aminoglycosides
    Clindamycin
    Cephalosporins
    Sulfinamides

    1 points

    Question 20

    1.

    Which one is NOT the clinical use of Oxytocin


    Answer
    induction of labor
    induction of abortion
    augmentation of labor
    promote milk ejection
    postpartum hemorrhage

    1 points

    Question 21
    1.

    Which one is rapidly effective for acute


    asthmatic attack
    Answer
    oral administration of Aminophylline
    Cromoglicate sodium
    Aalbutamol inhalation
    Beclomethasone
    Ketotifen

    1 points

    Question 22
    1.

    Valsartan is
    Answer
    Ca2+ channel blocker
    -blockers
    Cardiac Glycosides
    Angiotensin II receptor blockers (ARBs)
    Angiotensin-Converting Enzyme Inhibitor(ACEI)

    1 points

    Question 23
    1.

    For the roundwarm and pinwarm infection,


    preferred drug is
    Answer
    Praziquantel
    Levamizole
    Mebendazole

    Piperazine
    Pyrantel

    1 points

    Question 24
    1.

    Penicillin G is the 1st choice against


    Answer
    Gbacillus
    Hemolytic Streptococcus
    Mycobacterium tuberculosis
    Enterococci
    Shigellosis

    1 points

    Question 25
    1.

    The mechanism action of Heparin is


    Answer
    block the Ca++ action
    active the ATIII

    counteract to the VitK


    antagonize the VitK effect
    "inhibit the synthesis of thrombin II , IX, X"

    1 points

    Question 26
    1.

    A 35-year-old female complains of itching in


    the vulval area. Hangingdrop examination of
    the urine reveals trichomonads. What is the
    preferred treatment for trichomoniasis?
    Answer
    Emetine
    Metronidazole
    Pyrimetamine
    Pentamidine
    Doxycycline

    1 points

    Question 27
    1.

    The mechanism of Glucocorticoids for asthma


    treatment is
    Answer
    stimulate respiratory centre
    activate adenyl cyclase
    dilate airway smooth muscles
    anti-inflammation and anti-allergy
    block M-receptor

    1 points

    Question 28
    1.

    Adverse Effects of Angiotensin Converting


    Enzyme (ACE) Inhibitors are NOT including
    Answer
    Ventricular bradycardia
    Hypotension
    Hyperkalemia
    Angioneurotic edema
    Cough

    1 points

    Question 29
    1.

    What is the mechanism action of Zidovudine


    Answer
    Inhibition of nucleoside reverse transcriptase
    Inhibition of DNA synthesis
    Inhibition of viral particle assembly
    Inhibition of RNA synthesis
    Inhibition of viral proteases

    1 points

    Question 30
    1.

    Which agents using should be cautious about


    or avoided while patient underwent kiney
    malfunction?
    Answer
    Penicillins
    Macrolides

    Tetracyclines
    Aminoglycosides
    Chloramphenicol

    1 points

    Question 31
    1.

    The mechanism of action of Biguanides is


    Answer
    increase the glycagon effect
    decrease insulin resistance
    enhance the glucose uptake and catalyzing by peripheral
    tissues
    stimulating insulin release from pancreatic cells
    promote the glucose to catalyze

    1 points

    Question 32
    1.

    Cardiac output is best increased by


    stimulation of
    Answer

    beta1 receptors
    muscarinic receptors
    beta2 receptors
    alpha2 receptors
    alpha1 receptors

    1 points

    Question 33
    1.

    The Thioureas can be used for


    Answer
    hypothyroidism
    diabetes
    hyperthyroidism
    hypogonadism
    allergy

    1 points

    Question 34
    1.

    Which one is NOT a first-line


    antituberculosis agents?
    Answer
    Isoniazid
    Ethambutol
    Rifampin
    Pyrazinamide
    Amikacin

    1 points

    Question 35
    1.

    The mechanism of action of Sulfonylureas is


    Answer
    increase the glycagon effect
    decrease insulin resistance
    inhibit the insulin effect
    promote the glucose to catalyze
    stimulating insulin release from pancreatic cells

    1 points

    Question 36
    1.

    Which description about Generation III


    Quinolones is WRONG?
    Answer
    Levofloxacin is most effective vs. G germs in the family
    They act against G germs by inhibiting DNA gyrase
    They are chlorine derivatives of Pipemidic acid
    They act against G germs by inhibiting DNA topoisomerase IV
    They have strong activity against G germs

    1 points

    Question 37
    1.

    Which agent act against bacteria mainly by


    interfering functions of cell membrane?
    Answer
    ciprofloxacin
    polymyxin B
    streptomycin

    erythromycin
    tetracycline

    1 points

    Question 38
    1.

    Which drug is effective against either


    systemic or superficial fungal infection?
    Answer
    Flucytosine
    Ketoconazole
    Nystatin
    Amphotericin B
    Ribavirin

    1 points

    Question 39
    1.

    Which one in the following drug is best to


    treat hypertension crisis
    Answer

    Spironolactone
    Losartan
    Sodium Nitroprusside
    Captopril
    Hydrochlorothiazide

    1 points

    Question 40
    1.

    Hypokalaemia occurs with the following drugs


    Answer
    Captopril
    Bumetanide
    Nifedipine
    Carbonic anhydrase inhibitors
    Spironolactone

    1 points

    Question 41
    1.

    Prodrug-requires activation by microsomal


    enzyme system
    Answer
    cyclophosphamide (Cytoxan)
    chlorambucil (Leukeran)
    thiopeta (Thioplex)
    mechlorethamine (Mustargen)
    semustine (methyl CCNU)

    1 points

    Question 42
    1.

    Why the clinical use of Choloramphenicol is


    limited in infectious disease?
    Answer
    Severe adverse effects such as irreversible marrow inhibition
    Low bioavailability
    Most bacteria have developed drug resistance
    Low efficiency in suppressing bacteria
    Severe allergic shock

    1 points

    Question 43
    1.

    Which one does NOT have the effect of


    antiplatelet aggregation
    Answer
    Aspirin
    Wafarin
    Dipyridamole
    Ridogrel
    Epoprostenol

    1 points

    Question 44
    1.

    Which of the following is NOT the adverse


    effects of Glucocorticoid ?
    Answer
    poor wound healing
    asthma

    "buffalo hump, moon face"


    osteoporosis
    hypertension

    1 points

    Question 45
    1.

    Omeprazole is belonged to
    Answer
    H1 receptor antagonists
    H2 receptor antagonists
    M receptor antagonists
    Mucosal protective agents
    H+-K+-ATPase (Proton pump) inhibitor

    1 points

    Question 46
    1.

    A 25-year-old female post-renal transplant


    shows signs of acute renal allograph

    rejection. Of the following agents, which


    should be administered?
    Answer
    Acyclovir
    Interleukin-2
    Levamisole
    Interferon
    Cyclosporin A

    1 points

    Question 47
    1.

    By which target Aminoglycosides interfered


    with protein synthesis of bacteria?
    Answer
    stage of peptide strands exfliation
    stage of termination
    all stages of protein synthesis
    stage of initiation
    stage of peptide strands elongation

    1 points

    Question 48
    1.

    The phase of the cell cycle that is resistant


    to most chemotherapeutic angents and
    requires increased dosage to obtain a
    response is the
    Answer
    S phase
    M phase
    G0 phase
    G1 phase
    G2 phase

    1 points

    Question 49
    1.

    Which one in the following drugs is


    preferable to use to treat Paroxysmal
    supraventricular tachycardia
    Answer

    Amiodarone
    Verapamil
    Procainamide
    Lidocaine
    Atropine

    1 points

    Question 50
    1.

    Competitive inhibitor of
    3-hydroxy-3-methylglutaryl coenzyme A
    (HMG-CoA) reductase is
    Answer
    Cholestyramine
    Ezetimibe
    Simvastatin
    Acetazolamide
    Nicotinic acid

    1 points

    Question 51

    1.

    The effect mechanism of expectorant


    Acetylcystein is
    Answer
    breakdown the viscous component of the sputum
    decrease the protein secretion in the airway
    increase airway fluid secretion
    increase airway ciliary movement
    decrease sputum secretion

    1 points

    Question 52
    1.

    Which of the following description about the


    clinical uses of Glucocorticoid is WRONG
    Answer
    inhibit the growth of bacteria
    anti-shock
    anti-inflammatory effects
    immunosuppressive effects

    anti-allergic effect

    1 points

    Question 53
    1.

    Which drug can Increase nitric oxide (NO)


    Answer
    lonidine
    Aldosterone Antagonists
    Nifedipine
    Methyldopa
    Nitroprusside

    1 points

    Question 54
    1.

    Which drug is most effective against systemic


    fungal infection?
    Answer
    Terbinafine
    Nystatin

    Clotrimazole
    Amphotericin B
    Griseofulvin

    1 points

    Question 55
    1.

    Which of the following drugs is the first


    choice for the treatment of type I diabetes?
    Answer
    Angiotensin Converting Enzyme (ACE) Inhibitors
    Insulin
    Sulfonylureas
    Acarbose
    Biguanides

    1 points

    Question 56
    1.

    Which one in the following drugs is highly


    efficacious diuretics

    Answer
    Spironolactone
    Acetazolamide
    Hydrochlorothiazide
    Triamterene
    Furosemide

    1 points

    Question 57
    1.

    To treat bleeding induced by Warfarin, which


    drug can be used
    Answer
    Urokinase
    Vit K
    Vit B12
    Dipyridamole
    Protamine

    1 points

    Question 58

    1.

    Which agent is The 1st choice against MRSA?


    Answer
    Amoxicillin
    Generation 1 Cephalosoprins
    Vancomycin
    Penicillin G
    Erythromycin

    1 points

    Question 59
    1.

    Gentamicin inhibit bacterial protein


    synthesis by binding
    Answer
    30S ribosomal particles
    Messenger RNA
    RNA polymerase
    Peptidoglycan units in the cell wall
    DNA polymerase

    1 points

    Question 60
    1.

    The most effective drug to inhibit gastric


    acid secretion is
    Answer
    Calcium carbonate
    Cimetidine
    Proglumide
    Pirenzepine
    Omeprazole

    1 points

    Question 61
    1.

    Compare antibacterial characteristics of 4


    generations of Cephalosporins.
    Answer

    Question 62
    1.

    What is the clinical uses of Calcium Channel


    Blockers(CCBs).
    Answer

    Question 63
    1.

    List the adverse drug reactions (adverse


    effects) of Glucocorticoids in long-term
    use.
    Answer

    Question 64
    1.

    Please describe the therapeutic strategies


    and drugs for Peptic Ulcer.
    Answer

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