TURBOFER

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Iron deficiency is the most common nutritional disorder worldwide and a leading cause of anemia. It can have negative health consequences if left untreated, including increased mortality.

Iron deficiency is a lack of iron in the body. It is most commonly caused by inadequate dietary iron intake or blood loss. Left untreated, it can progress to anemia.

Common symptoms of iron deficiency include weakness, shortness of breath, headaches, fatigue, pale skin and impaired immune function.

Turbofer is a food supplement containing

iron pyrophosphate microencapsulated in liposomal form,


Vitamin B12, Vitamin C and folic acid with edulcorants

Iron deficiency (ID) is the most common nutritional disorder in the whole world and it is the leading cause of
anaemia (IDA). ID is considered to contribute to death and disability as a risk factor for maternal and perinatal
mortality, and also through its direct contributions to cognitive impairment, decreased work productivity and
death from severe anaemia. Better recognition of the disorder is essential to improve patient outcomes.
Although they frequently occur together, iron deficiency and anaemia are independent disorders, however, if
iron deficiency is left to advance to anaemia, it is harder to treat and associated with even worse outcomes;
recent research indicates that treating iron deficiency early on, before progression to anaemia, reduces mortality in comorbid conditions.

Prevalence of ID and IDA in the World


Regions

Population with Iron Deficiency


or Anemia (millions)

Prevalence of Anemia in
Pregnant Women (%)

Africa
The Americas
Europe
Eastern Mediterranean
Southeast Pacific
Western Pacific
Developed Countries
Developing Countries

206
94
27
149
616
1058

52
40
18
50
74
40
18
56

Total

2150

51

ID: Iron Deficiency; IDA: Iron Deficiency and Anemia

Successful management of iron deficiency replenishes iron stores, improves symptoms and limits the negative
clinical consequences associated with insufficient iron. These include increased morbidity, reduced quality of
life and, in some cases, mortality.

Symptoms of iron deficiency


Lethargy
Fatigue
Malaise/depression
Angina
Impaired cognition
Impaired immune system
Anorexia
Intolerance to cold
Endocrine/metabolic abnormalities
Cardiorespiratory disturnances
Gastrointestinal disturnances

Weakness
Shortness of breath
Exertional chest pain
Impaired concentration
Impaired libido/impotence
Insomnia
Headache
Pallor
Neuromuscular disturbance
Cutaneous disturbance

Tendency toward bleeding

Musculoskeletal symptoms

Reduce exercise tolerance

Pruritus

Treatment for iron deficiency usually involves taking iron supplements to replace missing iron. However
tolerance of oral treatments is generally low and the frequency and severity of side effects often leads to poor
compliance and to the necessity to start intravenous supplementation.
Common side effects seen with oral iron treatments
Constipation

Dyspepsia

Heartburn

Bloating

Nausea

Diarrhoea

TURBOFER: food supplement containing iron pyrophosphate microencapsulated in liposomal form, vitamin B12,
vitamin C and folic acid.

TURBOFER is an oral iron supplement that, thanks to its formulation,


provides adequate levels of iron without any unpleasant side effect.
IRON MICROENCAPSULATED IN LIPOSOMIAL FORM is a water dispersible micronized source of iron that has
been formulated to enhance iron absorption and to reduce undesirable organoleptic attributes, thus enabling the
oral supplementation of this essential nutrient.
Iron microencapsulated in liposomes improves iron absorption: iron pyrophosphate microencapsulated in liposomal
form travels through the high-acid stomach environment without interference from any compounds that it
encounters along the way. Thus the iron reaches the duodenum and the jejunum (the middle gastrointestinal tract),
where it is easily absorbed.
As a result, ferritin (the amount of iron stored in the body) and, in case of anemia, haemoglobin (a measure for
circulating iron) increase quickly and iron does not cause the stomach upset and constipation associated with the
high-dose iron tablets that doctors usually recommend.

Why
Innovative microencapsulated technology
Highly bioavailable
Maximum absorption-raises
hemoglobin and ferritin fast
No stomach upset, diarrhea, nausea
or other digestive symptoms

When
During pregnancy and lactation
In preconceptional period,
thanks to the presence of folic acid
In cases of heavy menstrual bleeding
or menometrorrhagia
In presence of various types of bleeding

No oxidation of fats and vitamins


No metallic taste or smell
Does not color mucous membrane
Non-constipating
Excellent tolerability
Total compliance

In case of frequent feeling of tiredness,


fatigue, weakness and asthenic symptoms
During sporting activity,
especially women of childbearing age
In children and adolescents
In low-calorie, vegetarian or unbalanced diets

Iron contributes to the formation of red blood cells and haemoglobin, while folic acid to the normal blood
formation. Vitamin C increases iron absorption. Vitamin B12, together with all the other components, contributes to the reduction of tiredness and fatigue.

Turbofer is a food supplement containing


iron pyrophosphate microencapsulated in liposomal form,
Vitamin B12, Vitamin C and folic acid with edulcorants

28 stick
Net weight 42 g

DOSAGE AND CONDITIONS OF USE In sticks which can dissolve quickly in the mouth without the need for water. Recommended dose: 1-2 stick daily at any time. Iron pyrophosphate microencapsulated in liposomal form is well tolerated at gastric level.
Turbofer can also be dissolved in water or fruit juice.
EXCIPIENTS Xilitab 200*, Mannitol, Orange Flavour, pH corrector: citric acid; edulcorants: Sorbitol, Aspartame, Sucralose,
Acesulfame K
%VNR

INGREDIENTS

Vitamin C

80 mg

100

Iron

14 mg

100

Folic acid

200 mcg

100

Vitamin B12

2,5 mcg

100

*NRV - daily Nutrient Reference Values

WARNINGS Do not exceed the recommended daily dose. Keep out of reach of children under three years of age. Food supplements are not intended as substitutes for a varied diet and a healthy lifestyle. It contains aspartame, a source of phenylalanine.
It contains polyols: excessive consumption may have laxative effects.
*Patented technologies by:
Blood. 2013 Dec 2. A systematic analysis of global anemia burden from 1990 to 2010.Kassebaum NJ, Jasrasaria R, Naghavi M, Wulf SK, Johns N, Lozano R, Regan M, Weatherall D, Chou DP, Eisele TP, Flaxman
SR, Pullan RL, Brooker SJ, Murray CJ.
Proc Nutr Soc. 2013 Nov 1:1-7. Iron deficiency during pregnancy: the consequences for placental function and fetal outcome.McArdle HJ, Gambling L, Kennedy C.
CMAJ. 2013 Nov 19;185(17):E791-802. Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials. Low M, Farrell A, Biggs BA,
Pasricha SR.
Clin Lab Med. 2013 Jun;33(2):281-91. Anemia in pregnancy. Horowitz KM, Ingardia CJ, Borgida AF.
J Womens Health (Larchmt). 2012 Dec;21(12):1282-9 Iron deficiency anemia in women across the life span. Friedman AJ, Chen Z, Ford P, Johnson CA, Lopez AM, Shander A, Waters JH, van Wyck D.

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