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Rheumatic heart disease is the most serious complication of rheumatic fever, which can occur in 0.3% of cases after streptococcal pharyngitis in children. Up to 39% of those with acute rheumatic fever may develop pancarditis with valve issues, heart failure, pericarditis, or death. Chronic rheumatic heart disease causes valve stenosis and regurgitation, atrial dilation, arrhythmias, and ventricular dysfunction, and it remains the leading cause of mitral valve stenosis in US adults. While decreasing in developed countries, rheumatic heart disease remains a major global health issue, estimated to affect 5-30 million children and young adults, killing 90,000 people each

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36 views1 page

Read Possible Background For Our Case

Rheumatic heart disease is the most serious complication of rheumatic fever, which can occur in 0.3% of cases after streptococcal pharyngitis in children. Up to 39% of those with acute rheumatic fever may develop pancarditis with valve issues, heart failure, pericarditis, or death. Chronic rheumatic heart disease causes valve stenosis and regurgitation, atrial dilation, arrhythmias, and ventricular dysfunction, and it remains the leading cause of mitral valve stenosis in US adults. While decreasing in developed countries, rheumatic heart disease remains a major global health issue, estimated to affect 5-30 million children and young adults, killing 90,000 people each

Uploaded by

jethro sanchez
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Background

Rheumatic heart disease is the most serious complication of rheumatic fever.


Acute rheumatic fever follows 0.3% of cases of group A beta-hemolytic
streptococcal pharyngitis in children. As many as 39% of patients with acute
rheumatic fever may develop varying degrees of pancarditis with associated
valve insufficiency, heart failure, pericarditis, and even death. With chronic
rheumatic heart disease, patients develop valve stenosis with varying degrees
of regurgitation, atrial dilation, arrhythmias, and ventricular dysfunction.
Chronic rheumatic heart disease remains the leading cause of mitral valve
stenosis and valve replacement in adults in the United States.

Acute rheumatic fever and rheumatic heart disease are thought to result from
an autoimmune response, but the exact pathogenesis remains unclear.
Although rheumatic heart disease was the leading cause of death 100 years
ago in people aged 5-20 years in the United States, incidence of this disease
has decreased in developed countries, and the mortality rate has dropped to
just above 0% since the 1960s. Worldwide, rheumatic heart disease remains a
major health problem. Chronic rheumatic heart disease is estimated to occur
in 5-30 million children and young adults; 90,000 individuals die from this
disease each year. The mortality rate from this disease remains 1-10%. A
comprehensive resource provided by the World Health Organization (WHO)
addresses the diagnosis and treatment. [1]

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