Peds Handbook 2017 - 2018
Peds Handbook 2017 - 2018
Peds Handbook 2017 - 2018
Topic
□ Pre-operative assessment
□ NPO guidelines
□ Pediatric anesthetic circuits
□ Fluid requirements
□ Blood administration and dosing
□ Induction techniques
□ Neonatal and pediatric physiology
□ Pediatric pharmacology
□ Pediatric advanced life support
□ Neonatal surgical emergencies:
□ Gastroschisis
□ Omphalocele
□ CDH
□ TEF
□ NEC
□ Myelomeningocele
□ Pyloromyotomy
□ Anesthetic concerns for preemies and neonates
□ Anesthetic concerns with a URI
□ Anesthetic management of a “bleeding tonsil”
□ Foreign body management
□ Croup vs. epiglottitis
□ Strabismus
□ Hydrocephalus
□ Caudal - doses, drugs, indications/contraindications, complications
□ Post-operative pain management options
□ Malignant Hyperthermia/AIR (Anesthesia-Induced Rhabdomyolysis)
□ Cardiac
□ Cyanotic congenital cardiac diseases
□ PDA
□ Tetrology of Fallot
□ Scoliosis
□ “Common” syndromes at Duke
□ Hurlers
□ Pierre Robin
4. Recommended references:
1. Baum and O’Flaherty. Anesthesia for genetic, metabolic, and dysmorphic
syndromes of childhood, 2007 (copy is in the CHC anesthesia office)
2. Gregory. PEDIATRIC ANESTHESIA. 2012
3. Davis. SMITH'S ANESTHESIA FOR INFANTS AND CHILDREN. 2017
4. Cote A Practice of Anesthesia in Infants and Children. 2013
5. THE HARRIET LANE HANDBOOK. 2017 (you may remember this from
medical school-it is good for doses of non-anesthetic drugs and basic pediatric
care)
5. Preoperative evaluation
A. Psychological appearance. A preop visit is the quickest way to evaluate the
behavior of the child and therefore, the preferred (planned) method of
anesthesia induction for the child.
B. History. Although the child's history may be unremarkable, there are a
large number of children at Duke that are veterans to the system and who
have extensive medical records. A complete history in pediatrics should
include the following conditions that will affect anesthetic management:
1. Prematurity and its implications (including residual lung disease, difficult IV
access, apnea, etc.)
2. Any associated anomalies?
3. Congenital heart disease and type of repair, if any.
4. Neurologic problems (often prolongs wake-up time unless
baseline mental status observed and considered)
5. Recent URI-important factor in scheduling of elective cases.
This is by no means a complete list, but hits a few of the high points most often missed
by the non-pediatrician.
C. Physical Exam:
1. Overall
2. Airway with loose teeth (age 5 is a good age to start asking)
3. Cardiac (murmurs?)
4. Lungs (wheeze, rhonchi, rales?)
5. Visible veins
D. Labs:
Indicated by age and planned surgery. Generally speaking, otherwise
healthy children undergoing elective surgery do not need routine labs drawn. Many of the
children we take care of have multi-system disorders and may be undergoing procedures
with the potential for blood loss. Consider pre-op labs in these patients. Blood can often
be drawn after the child is asleep (e.g. type and screen. Although remember the
automated system the blood bank currently uses take 45 minutes!). Discuss this with your
attending. You MUST think about pregnancy potential in teenage girls! Ask about
last menstrual period (that’s a medical question, not a social or lifestyle question and so a
reasonable place to start the conversation). Consider a beta-HCG if there is any question
of pregnancy. Again, ask you attending if you’re not sure. The preop holding nurses will
generally make sure urine HCG is ready for outpatient girls when appropriate, but an
order must be placed in EPIC (needs to be STAT). For inpatients that you see, THIS IS
YOUR RESPONSIBILITY!
E. A few definitions:
1. Neonate: up to one month of age
2. Infant: up to one year of age
3. Premature infant: #1 or #2, born before 37 weeks gestation
6. Premedication, NPO Status
Premedication prior to anesthesia is useful to alleviate anxiety and induce a calm state to
allow for a smoother mask induction or IV placement. Amnesia is also a common and
often desirable side effect.
The choice to premedicate a child is based upon several factors:
1. Your attending-some like it, some don't like it, and some patients
don't need it.
2. Age of the patient. Children <6 months of age do not yet have
separation anxiety and are not accompanied into the O.R. by their
parent. They are also not routinely premedicated. When children
are older than 6-12 months of age, there are a variety of methods and
reasons for premedication, including:
-Anxiety (of the patient: not you or the parent!).
-The planned surgery, the child's expectations, and previous
anesthetic experience.
-Ease of separation from parents
-Ease of IV placement
Midazolam:
Usual dose is 0.5 mg/kg PO (usual max 10-15mg), 20-30 minutes before induction.
Midazolam (as currently formulated) tastes bitter pretty terrible. We are basically giving
an oral dose of the concentrated IV form of the drug (5mg/mL). There are many ways to
administer it to minimize cruelty to the child (we're trying to help them, remember?).
Flavored syrup helps cover it up. A syringe is probably the best bet rather than in a cup.
Some children will spit out their premed no matter what you do. Parents are an important
resource in determining when this is likely to occur. The pre-op nurses will give it if you
tell them about it and put an order into Maestro Care for it (Look for the 5mg/mL form of
the drug-it’s in the “Preop Peds” order set). Nasal midazolam (0.3-0.5 mg/kg) is also
effective (skip the flavored syrup please) but quite noxious so not commonly used.
Dexmedetomidine:
Can be given as a premedication intra-nasally (1-2 mcg/kg) using the concentrated form
of the drug from pharmacy (not the IV form we usually give). Unfortunately, it takes
around 45 minutes to really work so it takes some planning.
The following is one of the most important things you will read today:
NPO orders for elective pediatric surgery
We use the ASA standard to determine this. For any age child, this means the minimum
acceptable time from ingestion is the following:
*Clear liquids 2 hours
Breast milk 4 hours
Formula, non-human
milk, #light meal 6 hours
Fatty foods 8 hours
*Clear liquids are water, apple juice, sprite, or other "see-through" sodas.
#The ASA says a “light meal” is toasted bread. Yum.
Be aware that these guidelines were intended for healthy patients undergoing outpatient
procedures. Many of our patients do not fit into these categories and this should be
taken into consideration. For example, patients with bowel issues (obstruction, short-gut,
etc.) may still be at risk for aspiration even though NPO, just like in adults. Also,
remember that fatty foods take longer to transit the stomach and 8+ hours is
probably a more appropriate fasting time if, for example, your patient stopped by
Bojangles for a biscuit on their way to the hospital.
Inpatients with intravenous lines should still adhere to the stricter NPO rules with
maintenance fluid being administered by IV during the fasting period. You are
responsible for double checking that NPO orders have been submitted in Maestro
Care on inpatient children prior to scheduled procedures. When doing so, keep in
mind that changes in the OR schedule sometimes occur. Be conservative, but reasonable.
If you have any questions, ask.
7. The Duke Children’s Health Center
The Children’s Health Center (CHC) is a facility that contains most of the pediatric
subspecialty clinics, including the surgical clinics. It also houses the preoperative and
PACU areas for children and overall is a terrific environment for children. All patients
with a pediatric surgeon will pass through this facility on the day of their surgery, as will
select children of non-pediatric surgeons. Most children will also have their preoperative
screening evaluation in the CHC by a member of the Preoperative Screening Unit team.
The pediatric anesthesia attendings review these preoperative evaluations and will
therefore often know about the patients before you do. You should still electronically
review the charts of outpatients on the day before surgery and be prepared to discuss the
anesthesia plans with your assigned attending the day/night before.
Get set up for the whole day before it begins. Many peds cases are short and you may
find that your OR has 5-6 cases or more in a day! You will often not have the time or
inclination to go to PACU, back to the pharmacy, back to the room to setup, back to
preop, and then back to the OR with the patient. If your room is pretty much ready for the
next patient when you leave for the PACU, you can page your tech to turnover, drop the
patient off in PACU, take the O2 tank to the next patient’s bed space in preop, talk to the
family and basically be ready to head into the OR for the next case after a quick check of
the OR setup. The preop nurses will give oral midazolam if they have an order for it (and
hopefully your attending did this before you got there!).
When setting up, have stuff ready but don’t open a bunch of things up that may not be
used. Trying to minimize waste and save the environment will help the kids you care for
have a better world to grow up in. Win-win.
There is a pharmacy in the CHC (first floor) so that families can get prescriptions filled
and an Einstein’s Bagels (T-level) so they can fill their stomachs as well.
8. Guidelines for operating room preparation
You may be doing a large number of cases in a relatively short period of time. The
bottom line is that you must start your set-up early in the morning for the cases you will
be doing over the day to avoid delays in between the cases. The set-ups need to be age-
appropriate and a variety of sizes of equipment and drugs will help to facilitate turnover
time. Have IV setups available for the whole day before you start your first case.
Anesthesia machine: Do your usual checkout and prepare your machine and circuit for
the size of your first patient.
Circuits: We use pediatric circle system for infants and children. The peds circuit (with
the smaller 1 liter bag) is a good choice for kids <30kg). Rarely, premature infants and
older children with significant lung disease will require an ICU ventilator. IV anesthesia
will be required in these cases.
Masks: Have two different sizes available for each patient at your fingertips.
Oral airways: Ditto. The one that looks too big usually fits.
Endotracheal tubes: Choose the size you feel is appropriate for your patient and also lay
out a size larger and one smaller (both unopened) so that you can change your plan easily
even with the scope in the mouth.
Guidelines for cuffed tubes:
Age Internal Diameter
Preemie 2-2.5mm
Term 3.0
3-9 mos. 3.5
9-12 mos. 4.0
18-24 mos. 4.0- 4.5
>24 mos. (age/4) + 3.5
You can actually measure the cuff pressure if you do use a cuffed ETT. There are
devices for this in the peds OR’s.
Correct depth of the endotracheal tube is easy to remember in infants:
Remember: "1-2-3/7-8-9" at the lips
1 kg => 7 cm depth
2 kg => 8 cm depth
3 kg => 9 cm depth
Larger infants and children...Tube size (ID) X 3 or Age + 11
Laryngoscope blades: It is often easier to use a straight blade in children less than 1 year
old (ask your attending why). Nevertheless, keep a backup (unopened) on your machine
for each case.
Laryngeal Mask Airway (LMA): Sizes exist to allow use with any age child (perhaps
excluding premature infants). Beware: the smaller the child, the more labor-intensive the
LMA can be. Choosing the right size and getting the proper fit are the keys to success with
the LMA. Sizing guidelines are as follows:
Size Weight Maximum Cuff Volume
#1 newborn up to 5 kg up to 4 ml
#1.5 5-10 kg up to 7 ml
#2 10-20 kg up to 10 ml
#2.5 20-30 kg up to 14 ml
#3 >30 kg up to 20 ml
Drugs:
1. Atropine in 1ml syringe with a 22g needle.
2. Succinylcholine in syringe large enough to hold 4 mg/kg
(the IM dose used in an emergency) with a 22g needle.
3. Nondepolarizing drug of choice (if needed) in appropriately sized
syringe. We usually use Rocuronium.
4. Syringes of flush to push meds, salvage IVs, etc.
5. Propofol in the room, drawn up in a volume to allow 3+ mg/kg
6. Analgesic (Fentanyl, morphine or ketorolac as indicated)
7. Ketamine. Used for some cases but rarely.
8. Epinephrine 10 mcg/mL, 100mcg/mL (and 1 mcg/mL for <10kg) (on Omnicell)
9. Lidocaine in syringe large enough for 2 mg/kg
Does all of this seem like a lot to remember? There’s a “cheat sheet” in each of the Peds
OR’s that outlines this for your reference.
Note:
With the exception of antibiotics, choose the appropriate size syringes based on the patient’s
weight and expected dosing then fill up your syringes with drug. In other words, don’t
put a single dose of medication in a syringe (partially filled)! A full syringe means it’s
clean. A half filled syringe looks used. Since we often do so many cases, this helps keep it
safe for all the children. The Codonics machine makes labels for you. Scan the vials and
voila! Use it!
IV fluids: Use a buretrol IV setup for all children < 30 kg. Set up your fluids with a
buretrol, stopcock with extension and t-piece. NOTE: Larger children (>8y.o., 30kg) do not
need the buretrol in most cases and should get a regular IV drip (not a minidrip). Fill the
buretrol to no more than 10 ml/kg to avoid flooding your tiny patients.
Be sure to clear lines of bubbles of air as children often have undiagnosed septal defects.
Please keep track of the fluids you put into the buretrol by writing the amount on the side
of it (see discussion and picture below on how to do this).
Regarding IV’s, please make every attempt to keep stopcocks capped when not in use and
to clean needleless connections with an alcohol wipe EVERY TIME you administer a
drug. Many of our patients have central lines that are at risk of getting
contaminated/infected and a sizable number of these patients are immunocompromised for
a variety of reasons. If you get in the habit of maintaining an aseptic technique for every
IV and every drug administration, you will protect those at low risk and those at high risk
for infection. Dr. Eck is a germophobe and is watching you. J
Note on resuscitation drugs:
Our faculty have agreed that epinephrine should be available for resuscitation. In order to
keep it safe, the epinephrine should be prepared as outlined:
To be clear, DON’T DO THIS!:
Adding any drug to a prefilled saline flush syringe, no matter how it’s labelled
is a setup for a medication error when someone grabs it thinking it is flush.
Dilute drugs in separate, clean syringes and label appropriately.
Pediatric Anesthesia Guidelines for Room Preparation
Endotracheal Tubes
Calculate the size expected based on age
Have that tube, one size larger, and one size smaller
Stylet tubes that are < size 3.5
Straight blades are typically used for children < 1 y.o.
Drugs
For ALL cases, have succinylcholine and atropine drawn up in syringes with 22
gauge needles for possible IM use. Place these on the anesthesia machine.
Other drugs are to be drawn up on an individual case basis
Syringes
Use 1 cc syringes if patient weighs < 5 kg
Pay attention to weight and max doses to determine when to use 3 vs. 5 cc
syringes for other pediatric cases
Circuits
Use pediatric circle system for all cases < 30 kg
Fluids
Buretrols should be used for all children <30kg (regular drip if >30kg)
Fill the buretrol to no more than 10 cc/kg
There should be at least 1 dextrose-containing solution for neonates/ICN babies,
running on an infusion pump.
Monito
Monitors
Note there are two types of disposable pulse ox probes to use according to the weight of the
patient:
Do not draw up needless drugs or use expensive supplies such as special endotracheal
tubes without reason. Be prepared for all cases for the day to avoid delays. If there are
any questions, ask your attending.
CLEAN UP AFTER YOURSELF!
Before you leave for the day, please make sure to discard or restock any disposable
supplies that you prepared and did not use. Leave the OR space clean and tidy. Don’t
expect others to clean up after you!
If you pulled extra equipment into the OR that is not normally stocked in there (e.g.
epidural or central line kits), that needs to be restocked outside of the OR itself, make
sure those items are placed in the designated space for restocking.
9. Fluid and blood replacement
Here’s how to do the fluids in the OR with the Maestro Care record:
Start each bag of fluid in the record with “New Bag” note to indicate that you’ve started
the IV.
Put a piece of tape on the buretrol noting the amount of fluid you put in to start (100 cc
for example but no more than 10cc/kg). When it’s empty, fill it again to whatever
amount you choose. Cross out the first amount and write in the second. Document
each of these increments in the Maestro Care record for each IV separately. If you do
this every time you fill the buretrol, you will easily know what you have given just by
looking at the buretrol. If you keep a running total on outside of the buretrol(s), you
will always know how much fluid you have given, even if you have more than one IV.
Basically, you are keeping track of the fluids separately and putting each aliquot into the
Maestro Care record. Anyone coming into the room can immediately tell without having
to scroll around the record and fluids are unlikely to be “lost” in the record. If you don’t
keep track this way, you will likely not be able to keep track of how much you’ve given,
especially with infants because unlike with adults and older children, you can’t just look
at the bag and tell how much you’ve given with any precision. In the photo above, 250
mL have been administered so far.
1. Maintenance IV fluids:
4 ml/kg 0-10 kg plus
2 ml/kg 10-20 kg plus
1 ml/kg >20 kg
2. Suitable boluses are 10cc/kg at a time. Use Crystalloid, plasmanate (or other Colloid).
3. Each 1-1.5ml/kg of pRBC's will raise the Hct by about 1%.
4. 1 unit/10kg of platelets will raise the count by 20-25,000.
To estimate blood replacement
Vol of PRBCs = [(decimal)Desired Hct - Current Hct] x Est Blood Vol x 1.5
Example (6 month old, 7 kg), Hct 20 and goal Hct is 30: